Brain weights correlate with behavioral parameters in individual inbred mice housed in a common and enriched environment

Fifty 8-week-old Balb/c mice were individually identified and housed together in a large and enriched environment for 5 months. Maze and open field exploration, response to an aversive noise, swimming, and induced grooming tests were applied to each mouse in an initial search for possible relationships between brain morphology and spontaneous behavior in isogenic individuals living in a complex social and physical environment. The tasks generated 39 quantitative behavioral indices which include locomotion, rearing, still, and grooming bout frequencies, latencies, total, and mean bout durations. At the end of the tests, the 7-month-old mice were sacrificed and the fresh weights of their whole brain, cerebellum, brain stem, diencephalon, telencephalon, and prosencephalon were rapidly obtained. Behavioral data have wide variations and do not adjust to normal population distributions. Means of the same parameter differ between tests. A Spearman correlation matrix of all data yielded many significant correlations between indices of the same task which can be interpreted in terms of time budget and sequence probability. Significant correlations between indices of different tests suggest diverse emotionalities, exploratory strategies, and motor skills. The correlations between body and brain weights and among separate brain regions were not significant. There were several low but significant correlations between brain weights and behavioral indices. Such correlations, the resulting factors, and significant behavioral differences between mice with large and small brains suggest that mice displaying low motor activity in novel environments have larger brains and forebrain/hindbrain ratios than mice with high activity, and that animals with high scores of some specific behaviors have larger brain areas physiologically related to such behaviors.(ABSTRACT TRUNCATED AT 250 WORDS)     

Truthlikeness without truth: A methodological approach

In this paper, an attempt is made to solve various problems posed to current theories of verisimilitude: (1) the (Miller's) problem of linguistic variance; (2) the problem of which are the best scientific methods for getting the most verisimilar theories; and (3) the question of the ontological commitment in scientific theories. As a result of my solution ot these problems, and with the help of other considerations of epistemological character, I conclude that the notion of Tarskian truth is dispensable in a rational (and realist) interpretation of the scientific enterprise. As a logical result, however, falsificationism will be vindicated.

... and in brief, a speaker must always aim at verisimilitude, and send the truth packing.

Plato,Phaedrus, 272 EI want to express my gratitude to Professors García-Bermejo, Niiniluoto, and Zofío for interesting comments and critiques of several of the ideas in this paper, and to Miss Karen Firnich for correcting my English. I am also thankful to an anonymous referee who indicated several dark points on a previous version of my article.     

The psychological cost of waiting

The study of any problem involving waiting situations invariably assumes that people dislike having to wait. The analysis of queueing problems usually prescribes that some costs should be associated with the time people spend waiting to be served. These are usually considered to be of an economic nature, though the existence of other costs of a psychological nature is accepted. It is generally accepted that after having to wait for a certain amount of time, anxiety and stress start to build up in an individual, due both to the sense of waste and the uncertainty involved in a waiting situation. This work provides a theoretical basis for analysing this building up process as it occurs during the waiting period. It is proved that, under very general conditions, the resulting psychological stress accumulated during the process is a marginal increasing function of the waiting time, and some strategies to minimise it are developed. The results obtained give theoretical support to the usual assumptions underlying the development of systems to provide “real time” information to people in waiting situations. This is especially important in the operation of public transportation systems. The results also provide theoretical support to the “convex” treatment usually given to the waiting cost function in queueing problems.     

Social structure features in three inbred strains of mice, C57Bl/6J, Balb/cj, and NIH: a comparative study

Some features of social living were investigated in three inbred strains of mice: C57Bl/6j, Balb/cj, and NIH. Five social behaviors--Aggression, Submission, Allogrooming, Social Rest and Rest Alone, as well as Wheel Running Activity--were recorded 2 h daily for a week, in 26 groups of seven male mice living in an enriched environment. Dominants and subordinates among strains shared some behavioral characteristics, but strain contributions upon social structure were also detected. Similarities among strains included the appearance of a single dominant mouse per group rated as the most aggressive, besides from being the animal presented with most Submissions. Allogrooming was more frequent among subordinates than among dominants and subordinates. Differences among strains were that agonistic behavior among subordinates was higher in the Balb/cj and NIH groups than in the C57Bl/6j mice. NIH mice were recorded in Rest Alone more often than mice from the other strains. C57Bl/6j dominants showed higher rates of Wheel Running Activity than subordinates.     

Three-dimensional perspective drawing of two-dimensional functions with microcomputers

In this paper, we present a BASIC program for Apple II series computers that allows the user to obtain perspective drawings of two-dimensional functions of known analytical expression. Also, we outline a procedure for obtaining perspective representations of two-dimensional arrays of data using the same program. The program should run on any computer with graphics mode with only slight modifications in the graphics commands.     

Social reciprocity in handicapped and nonhandicapped children in a dyadic play situation

Social reciprocity behavior was compared for handicapped and nonhandicapped preschool children when they were in play situations with both handicapped and nonhandicapped partners. In a counterbalanced design, handicapped and nonhandicapped children were paired with both handicapped and nonhandicapped play partners, and the social initiation and response sequences of the dyads were observed. Types of initiation observed were friendly statements, friendly questions, mildly negative advances, and demanding statements. Friendly, ignoring, and negative responses were observed to these initiations. Handicapped and nonhandicapped children did not differ on overall number of initiations. However, they did differ on the types of initiation they made. Handicapped children asked fewer friendly questions and engaged in more demanding initiations than expected. Both groups made more initiations when paired with handicapped partners than when paired with nonhandicapped partners, but the groups did not differ on the types of initiation made to handicapped and nonhandicapped partners. The handicapped children made more ignoring and negative responses to friendly initiations than the nonhandicapped children. Behaving similarly, both groups tended to respond negatively to negative and demanding initiations.     

“Put a Little Love in Your Heart”: Acceptance of Paternalistic and Ally Political Discourses Both Predict Pro-Roma Solidarity Intentions Through Moral Inclusion

The way politicians talk about minorities institutes the normative context of intergroup relations. We investigated how endorsement of different political discourses predicts donation and collective action intentions by majority members toward the Roma in five European countries. The survey was conducted online using samples demographically similar to the populations of Hungary, Slovakia, Romania, France, and Ireland (N = 5,054). First, results showed that accepting paternalistic discourse versus discourse promoting allyship were not distinguishable; both promoted higher moral inclusion which in turn predicted higher prosocial intentions. Second, donations (i.e., immediate relief) and collective action (i.e., social change action) were driven by identical factors. Third, acceptance of openly hostile political discourse neither predicted moral exclusion, nor lower prosocial intentions. In summary, our research provides important evidence that when it comes to Roma—non-Roma relations, the previously established distinction between solidarity intentions that aim to solidify status relations versus bring about social change is completely blurred, presumably because of the social context in which any positive message communicates moral inclusion challenging the hostile status quo.     

A review on equivalence-based procedures to teach food-portion estimation skills

This review involved a systematic analysis of equivalence-based instruction (EBI) that aimed to improve food-size interventions in diverse populations. Systematic searches identified seven studies published since 2010 that met inclusion criteria. These studies were analyzed according to their participants, design, setting, content taught, training structures, training protocol, testing format, treatment integrity, and outcomes. Results showed EBI procedures for teaching food estimation skills have been mostly implemented with adults. The type of content taught in the identified studies included carbohydrate ranges, portion size with food and non-food items, measuring cups and nutritional content of calories. Majority of included studies used one-to-many training structure and simultaneous protocols for teaching stimulus relations. Five studies completed a generalization probe and three studies reported treatment integrity data. Overall, all participants demonstrated skill acquisition of novel relations between food and portion measurement aides. Recommendations for future research and clinical applications of EBI in teaching food portion estimation are presented.