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Nanoparticles have multifaceted advantages in drug administration as vaccine delivery and hence hold promises for improving
protection of farmed fish against diseases caused by pathogens. However, there are concerns that the benefits associated with
distribution of nanoparticles may also be accompanied with risks to the environment and health. The complexity of the natural
and social systems involved implies that the information acquired in quantified risk assessments may be inadequate for evidence-based
decisions. One controversial strategy for dealing with this kind of uncertainty is the precautionary principle. A few years
ago, an UNESCO expert group suggested a new approach for implementation of the principle. Here we compare the UNESCO principle
with earlier versions and explore the advantages and disadvantages by employing the UNESCO version to the use of PLGA nanoparticles
for delivery of vaccines in aquaculture. Finally, we discuss whether a combined scientific and ethical analysis that involves
the concept of responsibility will enable approaches that can provide a supplement to the precautionary principle as basis
for decision-making in areas of scientific uncertainty, such as the application of nanoparticles in the vaccination of farmed
fish. 相似文献
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Science and Engineering Ethics - This article presents and evaluates arguments supporting that an approval procedure for genome-edited organisms for food or feed should include a broad assessment... 相似文献
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