The KK-Principle, Margins for Error, and Safety

This paper considers, and rejects, three strategies aimed at showing that the KK-principle fails even in most favourable circumstances (all emerging from Williamson’s Knowledge and its Limits). The case against the final strategy provides positive grounds for thinking that the principle should hold good in such situations.     

Adapting Motivation,Control, and Compensation Research to A New Environment

The authors discuss the need to adapt research in three substantively related but paradigmatically diverse research domains (salesperson motivation, control systems, and compensation) in light of the evolving selling environment. A key objective is to suggest the desirability of integrating these literatures, which, ultimately, all seek to inform management regarding how salespeople and sales organizations can be encouraged to become more productive. The authors maintain that specification of the right goals and metrics constitutes a fundamental common denominator across the three literatures.     

A neglected response to the paradoxes of confirmation

Hempel's paradox of the ravens, and his take on it, are meant to be understood as being restricted to situations where we have no additional background information. According to him, in the absence of any such information, observations of FGs confirm the hypothesis that all Fs are G. In this paper I argue against this principle by way of considering two other paradoxes of confirmation, Goodman’s “grue” paradox and the “tacking” (or “irrelevant conjunct”) paradox. What these paradoxes reveal, I argue, is that a presumption of causal realism is required to ground any confirmation; but once we grant causal realism, we have no reason to accept the central principles giving rise to the paradoxes.     

Exercise therapy for depression in middle-aged and older adults: predictors of early dropout and treatment failure.

Psychosocial factors predicting treatment dropout or failure to benefit from treatment were identified in a randomized trial of exercise therapy and pharmacotherapy for major depression. One hundred fifty-six men and women over age 50 diagnosed with major depressive disorder were assigned to a 16-week program of aerobic exercise, medication (sertraline), or a combination of exercise and medication. Thirty-two patients (21%) failed to complete the program and were considered treatment "dropouts." At the end of 16 weeks, 83 patients (53%) were in remission; the remaining patients not in remission were considered treatment "failures." Baseline levels of self-reported anxiety and lift satisfaction were the best predictors of both patient dropout and treatment success or failure across all treatment conditions.     

Coenzyme Q10: a review of its promise as a neuroprotectant

Coenzyme Q10 (CoQ10) is a powerful antioxidant that buffers the potential adverse consequences of free radicals produced during oxidative phosphorylation in the inner mitochondrial membrane. Oxidative stress, resulting in glutathione loss and oxidative DNA and protein damage, has been implicated in many neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Experimental studies in animal models suggest that CoQ10 may protect against neuronal damage that is produced by ischemia, atherosclerosis and toxic injury. Though most have tended to be pilot studies, there are published preliminary clinical trials showing that CoQ10 may offer promise in many brain disorders. For example, a 16-month randomized, placebo-controlled pilot trial in 80 subjects with mild Parkinson's disease found significant benefits for oral CoQ10 1,200 mg/day to slow functional deterioration. However, to date, there are no published clinical trials of CoQ10 in Alzheimer's disease. Available data suggests that oral CoQ10 seems to be relatively safe and tolerated across the range of 300-2,400 mg/day. Randomized controlled trials are warranted to confirm CoQ10's safety and promise as a clinically effective neuroprotectant.     

How and why I arrived at a topsy-turvy account of Even-Ifs

Most philosophers of logic reject the prima facie plausible view that Even-If conditionals entail their consequents, and settle instead for accounts on which Even-Ifs entail the corresponding If-conditionals. In this paper, I provide fresh motivation for the rejected, consequent-entailing, view and sketch a pragmatic strategy to explain away seemingly proper, but apparently countervailing, uses.     

Assessment of a “Transgender Identity Stigma” scale among trans women in India: Findings from exploratory and confirmatory factor analyses

Background: Sexual minority stigma has been shown to influence mental health and sexual risk, but limited research is available on measuring transgender-identity stigma among trans women in India. We adapted an Exposure to Transphobia scale to the Indian context and tested a 14-item Transgender Identity Stigma Questionnaire (TGISQ) among trans women in India. We aimed to assess and validate the factor structure of the TGISQ and to assess its reliability.

Methods: Data were from a cross-sectional survey among 300 trans women (including hijras/thirunangais) from six urban/semi-urban sites in India. The TGISQ consisted of self-reported ratings on 14 items. We initially conducted exploratory factor analysis, using principal axis factoring (PAF) and promax rotation, and assessed reliability (internal consistency) using Cronbach's alpha; we then conducted confirmatory factor analysis to assess construct validity (factorial validity). Construct validity of the final 13-item Transgender Identity Stigma Scale (TGISS) was also examined by computing Pearson's correlations between TGISS and relevant theoretical constructs (e.g., depression, social support).

Results: PAF identified two factors: enacted stigma (5 items) and felt normative stigma (8 items). The final 13-item TGISS had high reliability and acceptable construct validity.

Conclusions: The TGISS was found to have adequate psychometric properties, making it the first valid and reliable scale to measure stigma and discrimination faced by trans women in India. Future studies can further refine TGISS, which might help in comparing the differences in stigma experiences among diverse subgroups of trans women, and in monitoring and evaluating the success of stigma reduction programs.     

Forgiven But Not Forgotten: Covert Uncertainty in Overt Responses and the Paradox of Defection‐Despite‐Trust

Despite the widespread belief that trust is a critical determinant of loyalty, empirical and anecdotal evidence calls into question the real‐world robustness of the trust–loyalty link. An important reason for the fuzzy nature of the trust–loyalty link may be the fuzzy nature of trust itself. That is, stated trust judgments embody both a magnitude dimension (i.e., the position along a favorable‐unfavorable continuum) and an uncertainty dimension (i.e., the lack of conviction with which the judgment is held). We investigated this possibility using data pertaining to consumers’ reactions to a service failure and the provider's success in responding to their complaints. We found that the interplay between dissatisfaction with the complaint handling and past experience simultaneously influences trust magnitude and trust uncertainty. However, these two dimensions of trust are shaped by different underlying processes. Finally, uncertainty dampens the impact of stated trust on loyalty.