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1.
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) catalyses the interconversion of active cortisol and corticosterone with inert cortisone and 11-dehydrocorticosterone, thus regulating glucocorticoid access to intracellular receptors. In rats, chronic glucocorticoid excess or stress increases 11beta-HSD-1 in the hippocampus, producing suggestions that it may attenuate the deleterious effects of chronic glucocorticoid excess. However, 11beta-HSD-1 predominantly catalyses 11beta-reduction in the intact liver and hippocampal cells, thus regenerating active glucocorticoids from inert substrate. We studied 11beta-HSD activity in the tissues of male tree shrews following 28 days of sustained psychosocial stress or exogenous administration of cortisol. In the hippocampus, chronic psychosocial stress attenuated 11-HSD-1 activity (69 +/- 9% of control), whereas cortisol alone had no effect. In the liver, both chronic stress and cortisol administration decreased 11beta-HSD-1 activity (47 +/- 11% and 49 +/- 4% fall, resp.). Attenuation of 11beta-HSD-1 within tissues may reflect a homeostatic mechanism designed to minimise the adverse effects of prolonged stress and/or glucocorticoid excess.  相似文献   
2.
The Memory Failures of Everyday Questionnaire (MFE) is one of the most widely-used instruments to assess memory failures in daily life. The original scale has nine response options, making it difficult to apply; we created a three-point scale (0-1-2) with response choices that make it easier to administer. We examined the two versions' equivalence in a sample of 193 participants between 19 and 64 years of age. The test-retest reliability and internal consistency of the version we propose were also computed in a sample of 113 people. Several indicators attest to the two forms' equivalence: the correlation between the items' means (r = .94; p < .001) and the order of the items' frequencies (r = .92; p < .001). However, the correlation between global scores on the two forms was not very high (r = .67; p < .001). The results indicate this new version has adequate reliability and internal consistency (r(xx) = .83; p < .001; alpha = .83; p < .001) equivalent to those of the MFE 1-9. The MFE 0-2 provides a brief, simple evaluation, so we recommend it for use in clinical practice as well as research.  相似文献   
3.
ABSTRACT

The so-called ‘Triple Frontier’—the border between Paraguay, Brazil, and Argentina—is the ‘host society’ of an important Muslim community, composed mainly of Lebanese immigrants and their descendants born in Brazil and Paraguay. In less than two decades, Shi’i and Sunni Arab Muslims created mosques, religious centres, a cemetery, and three schools. Mosques, schools, and religious centres are spaces for the production of a sense of community. The institutional discourse of these entities emphasises the connection between religion and community origin, considering Islam as part of ‘Arab culture’. Taking generational differences into account, this article aims to analyse the narratives of plural identity expressed in the meanings attributed to the immigrants’ self-identification as Muslims. Based on fieldwork in the South American border area, this work aims to shed light on the way in which immigrants and their descendants reinterpret their religious belonging, informed by the new experience of living in multi-religious societies.  相似文献   
4.
A primary criterion on which models of cognition are evaluated is their ability to fit empirical data. To understand the reason why a model yields a good or poor fit, it is necessary to determine the data-fitting potential (i.e., flexibility) of the model. In the first part of this article, methods for comparing models and studying their flexibility are reviewed, with a focus on parameter space partitioning (PSP), a general-purpose method for analyzing and comparing all classes of cognitive models. PSP is then demonstrated in the second part of the article in which two connectionist models of speech perception (TRACE and ARTphone) are compared to learn how design differences affect model flexibility.  相似文献   
5.
This paper addresses the importance of the concept of ideology in community work. The implications of a Marxist approach to ideology in community practice are analyzed in terms of the concepts of problematization (P. Freire, 1979) and consciousness-raising (J. Barreiro, 1976), illustrating the point with some examples. The traditional Marxist perspective is also examined in relation to the perspectives of social constructionism (I. Ibáñez, 1996), cultural studies (A. McRobbie, 1992), post-Marxism (E. Laclau & C. Mouffe, 1985), and feminism (D. Haraway, 1991). It is argued that the concepts of hegemony and habitus (P. Bourdieu, 1985) can be useful to community social psychology theory and practice. A situated perspective—in which it is possible to dialogue from different subject positions, and articulate transformation and political action—is argued. The implications of this shifting in the concept of ideology by means of theoretical developments outside social community psychology can help to define the external (outside) agent's position in community practice.  相似文献   
6.
7.
A gender perspective has been incorporated in transnational migration studies over the last two decades in Spain. According to feminist inquiry, research has focused mainly on four areas: transnational maternities, transformation in global care regimes, multiple discrimination experiences and change in gender relations by means of migration. In this paper, we suggest that there is a fifth area that has been neglected: one that studies the ways in which governmentality practices, performed within service provision aimed at migrant populations, are enacted in host societies. We argue that mechanisms of categorisation developed in service provision in Spain contribute to the construction of the category of “Third World Women”. A set of discourses and practices that are based on gender and cultural assignation related with stereotyped understandings of migrated women in host societies, situating them as suitable workers for current care regimes within these societies. These mechanisms have an important impact on life situations experienced by many migrated women as they are integrated into a low waged and undervalued work market. Further developments must be made in this last area of inquiry from a critical standpoint, in order to avoid the reproduction of discriminatory practices within institutional intervention settings.  相似文献   
8.
To update and expand Rubey and McIntosh's (1996) survivors of suicide support groups report, SPAN USA completed a survey of U.S. support group leaders (n = 100; 24% completion). There are now more survivor groups (from 280 to 417), and the majority of groups now have a survivor leader (78% vs. 25%). Groups continue to be small (88% < 10 members per session) and meet on a monthly basis (55%). Sharing continues to be a universal experience in groups, which tend to be open‐ended (85%). Current groups are newer, and more operate without a sponsor. Further research is needed to examine group member perspectives and effectiveness of groups.  相似文献   
9.
In this article, the concept of “media lifestyles” is adopted in order to develop a comprehensive approach toward youth engagement in communication media. We explore how 503 Dutch eighth grade students with full access to new technology combine a broad range of media by focusing on their engagement with media while taking various contexts of use into account. Four different media lifestyles of media omnivores, networkers, gamers, and low‐frequency users are described. Furthermore, we show how the methodology we used is able to provide more insight into how the distinguished media lifestyles were codetermined by particular media, functions and social contexts. Finally, the implications for the Uses & Gratifications theory are discussed.  相似文献   
10.
This article examines contemporary aspects of the identity construction of the ‘Alawi diaspora in Argentina. In the local context, the preservation of ‘Alawi singularity has so far been a key element in the group’s identity. The strategies for integration as legitimate Muslims in the wider Islam and the closeness to Shi’ism are relatively independent of how these processes took place in the homeland. I first describe the geography of the diaspora in Argentina, comprising the spaces and institutions where descendants settled all over the country. I analyze the factors that helped keep the nodes connected and I will demonstrate that these constitute a center/periphery logic for communities concerning the alleged degrees of preservation of the culture of origin they symbolize. I will try to show that ‘Alawis integrated into the diversity of Islam in Argentina while preserving their sectarian borders and, at the same time, stressing an “Arab” identity. I argue that these strategies should be understood in the local arena of an intra-Islamic pluralism that constitutes Muslim presence in Argentina, where the dynamics of sectarianisms assume idiosyncratic characteristics. Finally, I will show institutional closeness to Shi’ism as a recent development, promoted by the common political stance of both groups on the conflict in Syria. We will see that this closeness does not imply the dissolution of doctrinal boundaries between Shi’is and ‘Alawis and that it involves a redefinition of the diaspora in terms of increasingly claiming a Syrian national origin.  相似文献   
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