Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Connectionist modelling of the separable processing of consonants and vowels

describe two aphasic patients, with impaired processing of vowels and consonants, respectively. The impairments could not be captured according to the sonority hierarchy or in terms of a feature level analysis. Caramazza et al. claim that this dissociation demonstrates separate representation of the categories of vowels and consonants in speech processing. We present two connectionist models of the management of phonological representations. The models spontaneously develop separable processing of vowels and consonants. The models have two hidden layers and are given as input vowels and consonants represented in terms of their phonological distinctive features. The first model is presented with feature bundles one at a time and the hidden layers have to combine their output to reproduce a unified copy of the feature bundle. In the second model a "fine-coded" layer receives information about feature bundles in isolation, and a "coarse-coded" layer receives information about each feature bundle in the context of the prior and subsequent feature bundle. Coarse-coding facilitated processing of vowels and fine-coding processing of consonants. These models show that separable processing of vowels and consonants is an emergent effect of modular processors operating on feature-based representations. We argue that it is not necessary to postulate an independent level of representation for the consonant/vowel distinction, separate from phonological distinctive features.     

Pet Bereavement Support Groups: A Guide for Mental Health Professionals

Companion animals are becoming increasingly important in society. Pets have been recognized for their vast contributions to human lives, including emotional support, social support, health benefits, and connection. However, society does not recognize the significant loss associated with losing a pet, which can contribute to bereaved pet owners feeling isolation and shame as they cope with the loss of their beloved companion. Mental health professionals must be aware of this disenfranchised grief and creatively expand their services to provide support and advocacy for bereaved pet owners. This article includes a framework for clinicians to establish a pet loss support group in their community.     

The effect of repetition and similarity on sequence learning

Repetition is a pervasive feature of children’s environments, and may be an important contributor to learning such complex sequential structures as language. Endress, Dehaene-Lambertz, and Mehler (2007) found that repeated tone sequences were learned more easily than sequences containing ordinal relations, but there have been no direct comparisons of repeating sequences versus sequences that contain similar, but not identical, stimuli. In Experiment 1, we compared learning from repeating tone sequences to learning from tones that varied in similarity, and confirmed that repetition is a special case for learning. In Experiment 2 we showed that the learning distinction between repeated and similar elements is not affected by whether similarity is variable. We conclude by indicating that repetition provides an important constraint on learning, and we discuss the extent to which such constraints are consistent with general-purpose statistical learning mechanisms.     

Relationships between language structure and language learning: the suffixing preference and grammatical categorization

It is a reasonable assumption that universal properties of natural languages are not accidental. They occur either because they are underwritten by genetic code, because they assist in language processing or language learning, or due to some combination of the two. In this paper we investigate one such language universal: the suffixing preference across the world's languages, whereby inflections tend to be added to the end of words. A corpus analysis of child-directed speech in English found that suffixes were more accurate at cuing the grammatical category of the root word than were prefixes. An artificial language experiment found that there was a learning advantage for suffixes over prefixes in terms of grammatical categorization within an artificial language. The results are consistent with an account of language universals that originate in general purpose learning mechanisms.     

Reinforcer magnitude (sucrose concentration) and the matching law theory of response strength

This experiment investigated the relationship between reinforcer magnitude (sucrose concentration) and response rate. The purpose was to evaluate the behavior of two parameters of an equation that predicts absolute response rate as a function of reinforcement rate and two free parameters. According to Herrnstein's (1970) theory of reinforced behavior, one parameter of this "response-strength equation" measures the efficacy of the reinforcer maintaining responding and the other parameter measures motoric components of response rate, such as response duration. Seven rats served as subjects. Experimental sessions consisted of a series of five different variable-interval schedules of reinforcement, each in effect for 5 minutes. Within each session, obtained reinforcement rates varied over more than a 30-fold range, from about 20 per hour to 700 per hour. The reinforcer was sucrose solution, and, between sessions, its concentration was varied from 0.0 to 0.64 molar (0 to 21.9%). For sucrose concentrations of 0.16 to 0.64 m, response rate was a negatively accelerated function of reinforcement rate. Increases in sucrose concentration increased response rates maintained by low but not high reinforcement rates. This pattern of changes corresponds to a change in the reinforcement-efficacy parameter of the response-strength equation. In contrast, the motor-performance parameter did not change as a function of sucrose concentration. These findings are inconsistent with the results of a similar study (Bradshaw, Szabadi, & Bevan, 1978) but support Herrnstein's theory of reinforced behavior.     

Authoritative Parenting, Parenting Stress, and Self-Care in Pre-Adolescents with Type 1 Diabetes

Parent involvement in type 1 diabetes (T1DM) care leads to improved adherence; however, the manner in which parents approach illness management interactions with children must also be considered. It was hypothesized that greater use of an authoritative parenting style and less parenting stress would be associated with greater behavioral adherence and better metabolic control. Ninety-five primary caregivers of preadolescents (ages 8-11) with T1DM completed questionnaires assessing parenting style, pediatric parenting stress, and child behavioral adherence. Caregivers primarily self-identified as using an authoritative parenting style. Greater authoritative parenting was associated with greater behavioral adherence and less difficulty with pediatric parenting stress; no differences in metabolic control were observed. Greater engagement in authoritative parenting behaviors may contribute to increased age-appropriate child behavioral adherence and less pediatric parenting stress. Interventions highlighting diabetes-specific authoritative parenting techniques may enhance health outcomes and improve overall family functioning.     

Age of acquisition predicts rate of lexical evolution

The processes taking place during language acquisition are proposed to influence language evolution. However, evidence demonstrating the link between language learning and language evolution is, at best, indirect, constituting studies of laboratory-based artificial language learning studies or computational simulations of diachronic change. In the current study, a direct link between acquisition and evolution is established, showing that for two hundred fundamental vocabulary items, the age at which words are acquired is a predictor of the rate at which they have changed in studies of language evolution. Early-acquired words are more salient and easier to process than late-acquired words, and these early-acquired words are also more stably represented within the community’s language. Analysing the properties of these early-acquired words potentially provides insight into the origins of communication, highlighting features of words that have been ultra-conserved in language.     

Learning grammatical categories from distributional cues: Flexible frames for language acquisition

Performance in a behavioral task can be facilitated by associating stimulus properties with reward. In contrast, conflicting information is known to impede task performance. Here we investigated how reward associations influence the within-trial processing of conflicting information using a color-naming Stroop task in which a subset of ink colors (task-relevant dimension) was associated with monetary incentives. We found that color-naming performance was enhanced on trials with potential-reward versus those without. Moreover, in potential-reward trials, typical conflict-induced performance decrements were attenuated if the incongruent word (task-irrelevant dimension) was unrelated to reward. In contrast, incongruent words that were semantically related to reward-predicting ink colors interfered with performance in potential-reward trials and even more so in no-reward trials, despite the semantic meaning being entirely task-irrelevant. These observations imply that the prospect of reward enhances the processing of task-relevant stimulus information, whereas incongruent reward-related information in a task-irrelevant dimension can impede task performance.