Eyeblinking during autokinetic movement observed by a subject living in the up-down inverted visual world

Eyeblinking during autokinetic movement observed by one subject living in the up-down inverted visual world, was investigated. The subject wore frame-spectacles (without prisms) for the first two days and then wore up-down inverting spectacles (with prisms) for the next four days, followed by the resumption of the former frame-spectacles for one day. Eyeblinks during autokinetic movement were measured by using vertical EOG. Analysis showed (1) the occurrence of eyeblinking during autokinetic movement was not influenced by living in the up-down inverted visual world; (2) the frequency of eyeblinking during autokinetic movement significantly decreased with successive days of observation.     

Effects of up-down visual inversion on motor skills

The movement of a hand or fingers and locomotion of the body by a subject wearing prisms which inverted his visual world were investigated. A subject wore frame-spectacles (without prisms) for the first two days and then wore up-down inverting spectacles (with prisms) for the next four days, followed by wearing the former frame-spectacles again for one day. Measurements were made of skill on star-drawing, pegboard tests, and on zigzag-walking and walking up and down stairs. There were no differences on the five measures during acquisition for the four tasks, which suggests smooth progress of prism-adaptation by this man.     

Effects of living in the up-down inverted visual world on apparent movement

The purpose of this study was to examine whether a change of perceptual framework may affect the occurrence of apparent movement. Apparent movement was observed by one subject living over four days in the prismatically inverted visual world, because this situation was considered as the operation in which the subject was forced to change the perceptual framework to adapt himself to the novel environment. Apparent movement with two points was measured in vertical and horizontal configurations before wearing and after removing the prism as well as while wearing it. Analysis showed significant effects of prism-wearing on the occurrence of apparent movement in both vertical and horizontal configurations. Although further elaboration is required, an hypothesis was suggested from the viewpoint of the loss of visual position constancy.     

Developmental change in subjective probability during adolescence

The developmental change in subjective probability during adolescence, an important period for establishing the probability concept, was investigated. 75 Japanese adolescents, from 12 to 23 yr. of age, were asked to make probability judgments for a lottery under 15 conditions. Analysis showed that with increase in age their subjective probability came closer to the objective probability. Discussion of these results took into consideration recent studies on the development of the concept of probability.     

Involvement of BDNF receptor TrkB in spatial memory formation

The N-methyl-D-aspartate (NMDA) receptors are involved in long-term potentiation (LTP), and are phosphorylated by several tyrosine kinases including a Src-family tyrosine kinase Fyn. Brain-derived neurotrophic factor (BDNF) is a neurotrophin, which also enhances hippocampal synaptic transmission and efficacy by increasing NMDA receptor activity. Here, we show that Fyn is a key molecule linking the BDNF receptor TrkB with NMDA receptors, which play an important role in spatial memory formation in a radial arm maze. Spatial learning induced phosphorylation of TrkB, Fyn, and NR2B, but not NR2A, in the hippocampus. Fyn was coimmunoprecipitated with TrkB and NR2B, and this association was increased in well-trained rats compared with control animals. Continuous intracerebroventricular infusion of PP2, a tyrosine kinase inhibitor, in rats delayed memory acquisition in the radial arm maze, but PP2-treated animals reached the same level of learning as the controls. The phosphorylation of Fyn and NR2B, but not TrkB, was diminished by PP2 treatment. Our findings suggest the importance of interaction between BDNF/TrkB signaling and NMDA receptors for spatial memory in the hippocampus.     

Predictors of risk for smoking relapse in men and women: A prospective examination

The current study examined whether prequit trait negative mood and smoking motives have different predictive patterns of smoking relapse in men and women. Thirty-three female (mean age ± SEM: 34.9 ± 2.5) and 38 male (mean age ± SEM: 37.1 ± 2.3) smokers interested in smoking cessation completed forms on smoking history, negative mood (i.e., depression, anxiety, and anger), stress, and smoking motives. Participants also provided samples for measurement of cotinine and carbon monoxide. Then, they set a quit date and were required to abstain from smoking at least for 24 hours. Participants were followed up for 12 months postcessation to measure their smoking status. Cox proportional hazard models revealed that motivation to reduce craving was a unique predictor of smoking relapse in men, while depressive mood, anxiety, anger, and perceived stress were predictive of time to relapse among women. These findings remained significant after statistically controlling for smoking-related variables, providing preliminary evidence that different factors may be associated with nicotine withdrawal and smoking relapse in men and women. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Contributions of the striatum to learning, motivation, and performance: an associative account

It has long been recognized that the striatum is composed of distinct functional sub-units that are part of multiple cortico-striatal-thalamic circuits. Contemporary research has focused on the contribution of striatal sub-regions to three main phenomena: learning of associations between stimuli, actions and rewards; selection between competing response alternatives; and motivational modulation of motor behavior. Recent proposals have argued for a functional division of the striatum along these lines, attributing, for example, learning to one region and performance to another. Here, we consider empirical data from human and animal studies, as well as theoretical notions from both the psychological and computational literatures, and conclude that striatal sub-regions instead differ most clearly in terms of the associations being encoded in each region.     

Illusory continuity without sufficient sound energy to fill a temporal gap: Examples of crossing glide tones

The gap transfer illusion is an auditory illusion where a temporal gap inserted in a longer glide tone is perceived as if it were in a crossing shorter glide tone. Psychophysical and phenomenological experiments were conducted to examine the effects of sound-pressure-level (SPL) differences between crossing glides on the occurrence of the gap transfer illusion. We found that the subjective continuity-discontinuity of the crossing glides changed as a function of the relative level of the shorter glide to the level of the longer glide. When the relative level was approximately between -9 and +2 dB, listeners perceived the longer glide as continuous and the shorter glide as discontinuous, that is, the gap transfer illusion took place. The glides were perceived veridically below this range, that is, gap transfer did not take place, whereas above this range the longer glide and the shorter glide were both perceived as continuous. The fact that the longer glide could be perceived as continuous even when the crossing shorter glide was 9 dB weaker indicates that the longer glide's subjective continuity cannot be explained within the conventional framework of auditory organization, which assumes reallocation of sound energy from the shorter to the longer glide. The implicated mechanisms are discussed in terms of the temporal configuration of onsets and terminations and the time-frequency distribution of sound energy. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Spiritual Versus Religious Identity: A Necessary Distinction in Understanding Clinicians’ Behavior and Attitudes Toward Clinical Practice and Medical Student Teaching in This Realm

Social sciences view spirituality and religion separately; medicine views them together. We identified distinctions regarding clinical practice and teaching among clinician educators based on their self-identified spirituality versus religiosity. We emailed a 24-item survey on spiritual/religious (S/R) issues to clinician educators (n = 1,067) at our institution. Three summary scales were created. Responses to statements, ‘I consider myself to be spiritual’ and ‘I consider myself to be religious’ generated four comparison groups: ‘spiritual only,’ ‘religious only,’ ‘both spiritual and religious’ and ‘neither.’ Analyses employed ANOVA and T tests. A total of 633 (59 %) surveys were completed. Four percentage self-identified as ‘religious only’; remaining respondents divided evenly, about 30 % into each of the other categories. Groups differed from one another on all summary scales (p < .0001). Using T tests, the ‘spiritual only’ group differed from the ‘religious only’ group regarding teaching. The ‘spiritual and religious’ group had the highest mean ratings for all summary scales. The ‘neither’ and ‘religious only’ group had the lowest mean ratings. Clinicians’ spiritual versus religious identity is associated with differences in behavior/attitudes regarding S/R toward clinical practice and medical student teaching. These findings elucidate opportunities for faculty development to explore effects of beliefs on behavior and attitudes within this realm.     

Taste avoidance caused by spontaneous wheel running: effects of duration and delay of wheel confinement

Confinement of a rat in a running wheel results in the rat's subsequent avoidance of the taste consumed before the confinement. This phenomenon has been ascribed to taste aversion conditioned by spontaneous wheel running. As a first step toward clarification of the underlying mechanism of this phenomenon, we manipulated two parameters of the taste-confinement procedure: duration of wheel confinement (Experiments 1A and 1B) and temporal intervals between the taste consumption and the wheel confinement (Experiments 2A and 2B). In general, longer confinement and shorter inter-event interval caused stronger taste avoidance. However, the results also suggested that it is possible to establish taste avoidance when wheel confinement was delayed 1-h after the taste consumption. These results correspond to those of conventional taste aversion caused by illness-inducing agents, suggesting similar mechanisms in the both preparations. Experiment 3 revealed that running in a wheel rather than wheel confinement itself is the effective factor for establishing taste avoidance.