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Hippocampal extracellular acetylcholine (ACh) and choline levels were evaluated using in vivo microdialysis in male Fischer 344 rats before, during, and following an 80-min exposure to two different stress conditions. Measurements were taken in rats restrained and immersed in a water bath containing either 37 degreesC (normothermic-restraint) or 20 degreesC (cold-restraint) water. Results were compared to normothermic-freely-moving rats. Cold-restrained rats displayed decreased ACh levels during cold exposure relative to both normothermic-restrained and normothermic-freely-moving rats. By the end of the cold exposure period and following removal from cold, ACh levels had returned to near-baseline values. Normothermic-restrained rats had levels similar to those of normothermic-freely-moving rats, except for a marked increase in ACh following removal from restraint. Cold-restrained rats displayed a gradual elevation in choline levels during cold stress, followed by a gradual decline after stress termination, whereas both normothermic-restrained and normothermic-freely-moving rats displayed gradual decreases during the microdialysis session. These findings demonstrate that central cholinergic neurotransmission can be altered by the application of, and removal from, acute stressors. In addition, the results suggest a possible relationship between the magnitudes of both the stressor and its cholinergic consequences.  相似文献   
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The asymmetry of the posterior Sylvian branches of the middle cerebral artery was examined on the carotid angiograms of 59 patients in whom the lateralization of speech representation was known from sodium amobarbital (Amytal) studies. The usual asymmetry of these vessels was found to be present in the group of patients with left-hemisphere speech representation but significantly reduced in patients with atypical cerebral dominance for speech. A model of the inheritance of handedness and cerebral dominance is extended to take account of these results.  相似文献   
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The increase in pastoral-care systems in secondary schools over the last fifteen years is examined. It is suggested that pastoral care is more effective in allaying the anxieties of teachers and their organisations than it is in meeting the social and personal needs of pupils. It is also suggested that pastoral-care systems assume responsibilities which are more properly those of the family, and that the best way schools can offset the effects of poor home environments is via good subject teaching and increased pupil involvement in schools.  相似文献   
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The processing advantage for words in the right visual field (RVF) has often been assigned to parallel orthographic analysis by the left hemisphere and sequential by the right. The authors investigated this notion using the Reicher-Wheeler task to suppress influences of guesswork and an eye-tracker to ensure central fixation. RVF advantages obtained for all serial positions and identical U-shaped serial-position curves obtained for both visual fields (Experiments 1-4). These findings were not influenced by lexical constraint (Experiment 2) and were obtained with masked and nonmasked displays (Experiment 3). Moreover, words and nonwords produced similar serial-position effects in each field, but only RVF stimuli produced a word-nonword effect (Experiment 4). These findings support the notion that left-hemisphere function underlies the RVF advantage but not the notion that each hemisphere uses a different mode of orthographic analysis.  相似文献   
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When working as a member of a team, individuals must make decisions concerning the allocation of resources (e.g., effort) toward individual goals and team goals. As a result, individual and team goals, and feedback related to progress toward these goals, should be potent levers for affecting resource allocation decisions. This research develops a multilevel, multiple-goal model of individual and team regulatory processes that affect the allocation of resources across individual and team goals resulting in individual and team performance. On the basis of this model, predictions concerning the impact of individual and team performance feedback are examined empirically to evaluate the model and to understand the influence of feedback on regulatory processes and resource allocation. Two hundred thirty-seven participants were randomly formed into 79 teams of 3 that performed a simulated radar task that required teamwork. Results support the model and the predicted role of feedback in affecting the allocation of resources when individuals strive to accomplish both individual and team goals.  相似文献   
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This paper reports on a consultation exercise undertaken with 18 experienced counsellors on how they make client assessments. These practitioners expressed a high degree of consensus on the purposes of assessment making (to reach a shared understanding with the client about their willingness and ability to undertake a shared therapeutic journey) but the way in which they approached the task varied according to the theoretical orientation they acquired during training. Although most had developed their counselling skills and techniques considerably since initial training, not all had integrated the assessment implications of later experience into their formulation making. The implications of combining single model assessment with eclectic practice are discussed, particularly in relation to making a decision to continue working with a client or to refer a client to a colleague. The authors call for further debate on how counsellors find meaning in what their clients say, why they ask the questions they do at the assessment stage, and how they achieve coherence in relation to ideas and skills accrued through ongoing training and practice. The implications of such a debate for training and supervision are discussed.  相似文献   
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Insomnia leads to disrupted sleep and daytime fatigue. Many people who have this disorder look to the medical profession for treatment; however, it has been demonstrated that psychological approaches are usually more efficacious over the long term. Furthermore, such interventions are safe, cost effective, brief, and do not require extensive expertise. The authors provide an overview of the current best practices in assessment and treatment to encourage counselors to use these techniques when treating clients with insomnia.  相似文献   
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