Development of a Tissue Engineered Heart Valve for Pediatrics: A Case Study in Bioengineering Ethics

The following hypothetical case study was developed for bioengineering students and is concerned with choosing between two devices used for development of a pediatric tissue engineered heart valve (TEHV). This case is intended to elicit assessment of the devices, possible future outcomes, and ramifications of the decision making. It is framed in light of two predominant ethical theories: utilitarianism and rights of persons. After the case was presented to bioengineering graduate students, they voted on which device should be released. The results revealed that these bioengineering students preferred the more reliable (and substantially more expensive) design, though this choice precludes the majority of the world from having access to this technology. This case is intended to examine and explore where the balance lies between design, cost, and adequate distribution of biomedical devices.     

Matrix analysis of identifiability of some finite markov models

Methods developed by Bernbach [1966] and Millward [1969] permit increased generality in analyses of identifiability. Matrix equations are presented that solve part of the identifiability problem for a class of Markov models. Results of several earlier analyses are shown to involve special cases of the equations developed here. And it is shown that a general four-state chain has the same parameter space as an all-or-none model if and only if its representation with an observable absorbing state is lumpable into a Markov chain with three states.This research was supported by the U.S. Public Health Service under Grant MH-12717 to Indiana University and Grant GM-1231 to the University of Michigan.Now at the University of Texas, Austin.     

Effects of Simulated Learning and Facilitated Debriefing on Student Understanding of Mental Illness

Occupational therapy educators have studied various methods regarding student attitudes towards people with disabling conditions. Among the methods that have been studied is simulated learning. This paper describes the effects of a simulated learning exercise and facilitated debriefing on occupational therapy student understanding of mental illness. Results indicate that students had significant change relative to understanding that mental illnesses are brain diseases that respond to treatment (p < .01) on the post-test. Themes derived from qualitative data revealed that students believed that the learning experience increased their understanding, empathy, and insight into daily life with a mental illness.     

Evidence for task-dependent categorization in infancy

Two experiments compared infants' attention to the categorical distinction between people and animals in object-examining and sequential-touching tasks. In Experiment 1, 10- and 13-month-old infants distinguished between animals and people in an object-examining task. In this task, infants are familiarized with individual exemplars from one category, and then their response to exemplars from another category is measured. In Experiment 2, 13- and 16-month-old infants, but not 10-month-old infants, attended to the same distinction in a sequential-touching task. In this task, infants are presented with several exemplars from two categories simultaneously, and the order in which they touch those objects is assessed. Evaluation of infants' touching behavior in Experiment 2 also revealed developmental changes in how they approached this task. The combined results of these two experiments confirm the general trend reported in the literature and begin to provide insight into developmental changes that contribute to infants' ability to apply their categorization skills in different task contexts.