Family Augmented Cognitive Behavioural Therapy: Make Room for Mum!

Familial processes are gaining an increased amount of attention in cognitive behavioural therapy. Their role in initiating, maintaining, and exacerbating distress in children and adolescents has clear clinical implications. Therefore, including parents in their children’s therapy sessions as coaches, collaborators, and co-patients is becoming commonplace in CBT approaches to internalizing disorders such as anxiety. This article describes a case of a 13?year old female who presented with features of Generalized Anxiety Disorder and Separation Anxiety whose course of treatment involved her mother as a coach, collaborator and co-patient. A case formulation is offered and the specific examples of CBT practices used in each session are detailed. Ways of evaluating treatment outcome are also discussed.     

The Influence of Chronically Accessible Autonomous and Controlling Motives on Physical Activity Within an Extended Theory of Planned Behavior

An extended theory of planned behavior ( Ajzen, 1991 ), incorporating the post‐decisional phase of behavior and constructs from self‐determination theory ( Deci & Ryan, 1985 ), was tested for physical activity using a prospective survey design. Participants (N = 172) completed measures of intentions, attitudes, subjective norms, perceived behavioral control (PBC), self‐determined motivation, continuation intentions, and chronically accessible physical activity motives. Participants completed a self‐report measure of physical activity 3 weeks later. Path analysis supported the predictive utility of the proposed model. Importantly, the effect of continuation intentions of success on physical activity behavior was moderated by chronically accessible physical activity motives. Findings underscore the importance of taking into account continuation intentions, self‐determined motivation, and individuals' chronically accessible motives when developing physical‐activity‐promoting interventions.     

The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining

The basolateral complex of the amygdala (BLA) is critical for the acquisition and expression of Pavlovian fear conditioning in rats. Nonetheless, rats with neurotoxic BLA lesions can acquire conditional fear after overtraining (75 trials). The capacity of rats with BLA lesions to acquire fear memory may be mediated by the central nucleus of the amygdala (CEA). To examine this issue, we examined the influence of neurotoxic CEA lesions or reversible inactivation of the CEA on the acquisition and expression of conditional freezing after overtraining in rats. Rats with pretraining CEA lesions (whether alone or in combination with BLA lesions) did not acquire conditional freezing to either the conditioning context or an auditory conditional stimulus after extensive overtraining. Similarly, post-training lesions of the CEA or BLA prevented the expression of overtrained fear. Lastly, muscimol infusions into the CEA prevented both the acquisition and the expression of overtrained fear, demonstrating that the effects of CEA lesions are not likely due to the destruction of en passant axons. These results suggest that the CEA is essential for conditional freezing after Pavlovian fear conditioning. Moreover, overtraining may engage a compensatory fear conditioning circuit involving the CEA in animals with damage to the BLA.     

Acute starvation in C57BL/6J mice increases myocardial UCP2 and UCP3 protein expression levels and decreases mitochondrial bio-energetic function

Associations between uncoupling protein (UCP) expression and functional changes in myocardial mitochondrial bio-energetics have not been well studied during periods of starvation stress. Our aim was to study the effects of acute starvation, for 24 or 48 h, on combined cardiac mitochondrial function and UCP expression in mice. Isolated heart mitochondria from female mice starved for 48 h compared to that from mice fed revealed a significantly (p < 0.05) decreased adenosine diphosphate-to-oxygen ratio, a significantly increased proton leak and an increased GTP inhibition on palmitic acid-induced state 4 oxygen consumption (p < 0.05). These bio-energetic functional changes were associated with increases in mitochondrial UCP2 and UCP3 protein expression. In conclusion, our findings suggest that increased UCP2 and UCP3 levels may contribute to decreased myocardial mitochondrial bio-energetic function due to starvation.     

Career Compromise and Adjustment Among Graduates in the Banking Industry

A study is reported which aimed to examine several factors associated with career compromise and adjustment among 100 graduates in a bank. Contrary to predictions derived from Gottfredson's theory, satisfaction with the sextype of their jobs did not relate to perceptions of compromise; satisfaction with prestige explained some unique variance in compromise perceptions, but satisfaction with outlets for interests and use of skills and abilities were more important. Case data were used to explore other factors involved in the perception of career compromise. Qualitative data collected in the interviews with graduates highlighted several ways in which employers, graduates and career advisers can ease the transition from university to work.     

Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling

Prior research has focused on the latent structure of endophenotypic markers of schizophrenia liability, or schizotypy. The work supports the existence of 2 relatively distinct latent classes and derives largely from the taxometric analysis of psychometric values. The present study used finite mixture modeling as a technique for discerning latent structure and the laboratory-measured endophenotypes of sustained attention deficits and eye-tracking dysfunction as endophenotype indexes. In a large adult community sample (N=311), finite mixture analysis of the sustained attention index d' and 2 eye-tracking indexes (gain and catch-up saccade rate) revealed evidence for 2 latent components. A putative schizotypy class accounted for 27% of the sample. A supplementary maximum covariance taxometric analysis yielded highly consistent results. Subjects in the schizotypy component displayed higher rates of schizotypal personality features and an increased rate of treated schizophrenia in their 1st-degree biological relatives compared with subjects in the other component. Implications of these results are examined in light of major theories of schizophrenia liability, and methodological advantages of finite mixture modeling for psychopathology research, with particular emphasis on genomic issues, are discussed.     

Technological advances in the assessment of impulse control in offenders: A systematic review

Deficits in impulse control have been linked to criminal offending, risk of recidivism, and other maladaptive behaviours relevant to the criminal justice system (e.g. substance use). Impulse control can be conceptualized as encompassing the broad domains of response inhibition and impulsive/risky decision‐making. Advancements in technology have led to the development of computerized behavioural measures to assess performance in these domains, such as go/no‐go and delay discounting tasks. Despite a relatively large literature examining these tasks in offenders, findings are not universally consistent. This systematic review aims to synthesize the literature using computerized neurocognitive tasks to assess two domains of impulse control in offenders: response inhibition and impulsive/risky decision‐making. The review included 28 studies from diverse geographic locations, settings, and offender populations. The results largely support the general conclusion that offenders exhibit deficits in impulse control compared with non‐offenders, with studies of response inhibition more consistently reporting differences than studies using impulsive and risky decision‐making tasks. Findings are discussed in the context of contemporary neuroimaging research emphasizing dysfunction in prefrontal cortex as a key contributor to impulse control deficits in offenders.     

Priming of semantic autobiographical knowledge: a case study of retrograde amnesia

The case of a 36-year-old man who suffers dense retrograde and anterograde amnesia as a result of closed-head injury that caused extensive damage to his left frontal-parietal and right parieto-occipital lobes is described. Patient K.C. has normal intelligence and relatively well-preserved perceptual, linguistic, short-term memory, and reasoning abilities. He possesses some fragmentary general knowledge about his autobiographical past, but he does not remember a single personal event or happening from any time of his life. He has some preserved expert knowledge related to the work he did for 3 years before the onset of amnesia, although he has no personal recollections from that period. Some features of K.C.'s retrograde amnesia can be interpreted in terms of the distinction between episodic and semantic memory, and in terms of the distinction between episodic and semantic autobiographical knowledge. K.C.'s semantic knowledge, but not his episodic knowledge, showed progressive improvement, or priming, in the course of the investigation.