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Quillin JM McClish DK Jones RM Burruss K Bodurtha JN 《Journal of genetic counseling》2006,15(6):449-460
Differences in spiritual beliefs and practices could influence perceptions of the role of genetic risk factors on personal cancer risk. We explored spiritual coping and breast cancer risk perceptions among women with and without a reported family history of breast cancer. Analyses were conducted on data from 899 women in primary care clinics who did not have breast cancer. Structural equation modeling (SEM), linear, and logistic modeling tested an interaction of family history of breast cancer on the relationship between spiritual coping and risk perceptions. Overall analyses demonstrated an inverse relationship between spiritual coping and breast cancer risk perceptions and a modifying effect of family history. More frequent spiritual coping was associated with lower risk perceptions for women with positive family histories, but not for those with negative family histories. Results support further research in this area that could influence communication of risk information to cancer genetic counseling patients. 相似文献
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This study explored relationships between worry, perceived risk for breast cancer, consulting a genetic counselor, having
genetic testing, and genetic risk for women whose mothers had breast cancer. Analyses involved data from a community-based
phone survey of women whose mothers had breast cancer. Participants were categorized as having low, intermediate, or high
genetic risk based on their reported family history, in accordance with an accepted classification scheme. The Lerman Breast
Cancer Worry Scale measured worry, and participants reported their perceived lifetime likelihood of breast cancer, risk compared
to others, and chance from 1 to 100. ANOVA, chi-square, and multiple regression analyses were conducted as appropriate. One
hundred-fifty women participated. Mean age was 38 years, and 81% were Caucasian. Fifty-two women had low, 74 had intermediate,
and 24 had high genetic risk for breast cancer. There were no significant differences in worry or perceived risk by hereditary
risk category. Most high-risk women (91%) had not spoken with a genetic counselor, and no one had previous genetic testing.
These findings suggest perceived risk, worry about breast cancer, and use of expert consultation do not match the genetic
contribution to risk. There is a need for effectively stratifying and communicating risk in the community and providing tailored
reassurance or referral for high-risk assessment. 相似文献
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