Despite considerable experimental work on Alzheimer's disease (AD), the underlying cognitive mechanisms as well as the precise localization of neuropathological changes critical for memory loss remains undefined. A review of the neuropsychological literature on long-term memory deficits in AD patients suggests that AD patients display (a) a pervasive deficit of explicit memory, (b) a partial deficiency of implicit memory for verbal and visuoperceptual material (as measured by repetition priming procedures), and (c) a substantial sparing of implicit memory for visuomotor skills. The explicit memory loss is likely a result of encoding as well as consolidation difficulties. A faulty lexical-semantic knowledge structure appears responsible for deficient repetition priming effects. Since neuropathological changes diffusely affect the brain of AD patients, establishing a clear relationship between localization of cerebral lesions and memory deficits is particularly difficult. Nevertheless, data suggest that extensive involvement of the hippocampal-amygdala complex plays a major role in explicit memory loss. Damage to associative cortical areas likely is involved in repetition priming deficits. The relative integrity of primary motor and sensory cortical areas and of the basal ganglia likely subsume, by contrast, the normal learning of visuomotor skills. 相似文献
A study that involved parents as reading tutors was carried out at home during the summer with four elementary children, three with learning disabilities. One purpose was to determine the effects of tutoring in the basal reader on reading rates at home. Another purpose was to determine potential generalization effects as a result of parent tutoring on different academic tasks at home and, later at school, on different and similar tasks. A combination multiple-baseline and reversal design tested for replication and generalization effects. Increases in correct rates were noted for the targeted variables across conditions. The results indicated that parents tutoring with school basal texts during the summer produced marked increases in reading rates that generalized at home to different academic tasks and at school to different and similar tasks. This suggests that parents, when using specific tutoring procedures, can increase their children's academic skills. 相似文献
Two experiments investigated the role of lithium-mediated environmental conditioning on instrumental performance. Experiment 1 demonstrated that a novel taste consumed in one arm of a T maze prior to lithium-induced toxicosis reduced performance in this environment whereas similar aversions conditioned in the home cage failed to alter maze performance. Experiment 2 showed that maze performance in a straight alleyway was decremented during extinction only in a group that actually traversed the alley prior to drinking saccharin and receiving lithium injections. This demonstrated that the instrumental decrement observed in Experiment 1 was due not only to the presence of an unpalatable flavor in the goalbox during the test.
Five-year-old children were tested for perceptual trading relations between a temporal cue (silence duration) and a spectral cue (F1 onset frequency) for the “say-stay” distinction. Identification functions were obtained for two synthetic “say-stay” continua, each containing systematic variations in the amount of silence following the /s/ noise. In one continuum, the vocalic portion had a lower F1 onset than in the other continuum. Children showed a smaller trading relation than has been found with adults. They did not differ from adults, however, in their perception of an “ay-day” continuum formed by varying F1 onset frequency only. The results of a discrimination task in which the two acoustic cues were made to “cooperate” or “conflict” phonetically supported the notion of perceptual equivalence of the temporal and spectral cues along a single phonetic dimension. The results indicate that young children, like adults, perceptually integrate multiple cues to a speech contrast in a phonetically relevant manner, but that they may not give the same perceptual weights to the various cues as do adults. 相似文献
When teaching infants new actions, parents tend to modify their movements. Infants prefer these infant-directed actions (IDAs) over adult-directed actions and learn well from them. Yet, it remains unclear how parents’ action modulations capture infants’ attention. Typically, making movements larger than usual is thought to draw attention. Recent findings, however, suggest that parents might exploit movement variability to highlight actions. We hypothesized that variability in movement amplitude rather than higher amplitude is capturing infants’ attention during IDAs. Using EEG, we measured 15-month-olds’ brain activity while they were observing action demonstrations with normal, high, or variable amplitude movements. Infants’ theta power (4–5 Hz) in fronto-central channels was compared between conditions. Frontal theta was significantly higher, indicating stronger attentional engagement, in the variable compared to the other conditions. Computational modelling showed that infants’ frontal theta power was predicted best by how surprising each movement was. Thus, surprise induced by variability in movements rather than large movements alone engages infants’ attention during IDAs. Infants with higher theta power for variable movements were more likely to perform actions successfully and to explore objects novel in the context of the given goal. This highlights the brain mechanisms by which IDAs enhance infants’ attention, learning, and exploration. 相似文献
Groups of non-computer scientists were tested to evaluate the potential of an as yet non-existent interactive terminal with
a screen diagonal of one meter. A simulated large image terminal provided limited realistic interactions using software developed
to give close proximity to the predicted visual effect. Subjective responses from 101 subjects were elicited from a questionnaire
designed to evaluate specific aspects of the “terminal” in use. From this data, two types of screen (lenticular and plain)
and two types of interaction devices (touch and remote pointer) were analyzed experimentally using a two-way factorial design.
Potential end-users provided positive feedback concerning future use of the Large Image Terminal. Building a realistic mock-up
revealed screen contaminations which would not have been discovered until a much later stage. Although statistical analysis
of screen evaluations was equivocal, the questionnaire was sufficiently penetrating to separate the positive and negative
features. This methodology was invaluable in guiding the design process.
Copies of the questionnaire may be obtained from the authors at the Heriot-Watt address. 相似文献
Phonetic segments are coarticulated in speech. Accordingly, the articulatory and acoustic properties of the speech signal during the time frame traditionally identified with a given phoneme are highly context-sensitive. For example, due to carryover coarticulation, the front tongue-tip position for HI results in more fronted tongue-body contact for a /g/ preceded by /l/ than for a /g/ preceded by /r/. Perception by mature listeners shows a complementary sensitivity—when a synthetic /da/-/ga/ continuum is preceded by either /al/ or /ar/, adults hear more /g/s following HI rather than Irl. That is, some of the fronting information in the temporal domain of the stop is perceptually attributed to /l/ (Mann, 1980). We replicated this finding and extended it to a signaldetection test of discrimination with adults, using triads of disyllables. Three equidistant items from a /da/-/ga/ continuum were used preceded by /al/ and /ar/. In the identification test, adults had identified item ga5 as “ga”, and dal as “da”, following both /al/ and /ar/, whereas they identified the crucial item d/ga3 predominantly as “ga” after /al/ but as “da” after /ar/. In the discrimination test, they discriminated d/ga3 from dal preceded by /al/ but not /ar/; compatibly, they discriminated d/ga3 readily from ga5 preceded by /ar/ but poorly preceded by /al/. We obtained similar results with 4-month-old infants. Following habituation to either ald/ga3 or ard/ga3, infants heard either the corresponding ga5 or dal disyllable. As predicted, the infants discrimi-nated d/ga3 from dal following /al/ but not /ar/; conversely, they discriminated d/ga3 from ga5 following /ar/ but not /al/. The results suggest that prelinguistic infants disentangle consonant-consonant coarticulatory influences in speech in an adult-like fashion. 相似文献
A major critical issue in marriage and family therapy today is the professionalization of the discipline. Thus the focus on training individuals for a career in marriage and family therapy necessitates the revisitation of the debate over personal growth versus skill development. The trend toward training the person of the therapist, however, would suggest that the field is moving toward the integration of self awareness and skill in the therapeutic system. With the popularization of training the person of the therapist comes other issues, challenges, and dilemmas for the field, including the crucial issue of training gender and culturally sensitive therapists. The potential for creating dual relationships when training the person of the therapist is both a dilemma and a challenge. 相似文献