Advancing an Understanding of the Anxiety Control Questionnaire for Children (ACQ-C) in Clinically Anxious and Non-Anxious Youth: Psychometric Properties,Incremental Prediction and Developmental Differences

A lack of perceived control over anxiety-related situations is theorized to be characteristic of anxiety disorders in children and adolescents. In the current study we tested several theoretical predictions and developmental variation with the Dutch translation of the Anxiety Control Questionnaire for Children (ACQ-C). The theoretical factor structure of anxiety control was tested using Confirmatory Factor Analysis (CFA) in 548 non-referred children (8–18 years old, M?=?12.5 years; 50.7 % girls). The incremental predictive validity of perceived control for anxiety status was assessed using logistic regression in 141 clinically anxious children (age M?=?12.6 years; 56.7 % girls) and 298 non-referred non-anxious children (age M?=?12.6 years; 52.7 % girls). CFA showed that both a one-factor model and two-factor model (perceived control over internal reactions and external events) fit well. The one-factor model proved invariant across age and gender. Internal consistency was excellent (Cronbach’s α?=?.93). Two-month test-retest reliability was adequate. The ACQ-C was able to incrementally predict diagnostic status, even after controlling for age, gender and self-reported anxiety symptoms. Finally, both younger children and girls reported less perceived control, independent of anxiety level. Findings advance the understanding of the psychometric properties of the ACQ-C, the role of control in childhood anxiety and point to the potential utility of the ACQ-C in both clinical and community samples. The Dutch translation of the ACQ-C demonstrated sound psychometric properties.     

Human milk cortisol concentration predicts experimentally induced infant fear reactivity: moderation by infant sex

Little consideration has been given to the possibility of human infant development being shaped via lactocrine programming, and by breast milk cortisol levels specifically. Despite animal models indicating that glucocorticoid (GC) exposure via lactation might modify brain development and behavior, only one study has reported that milk cortisol levels were positively associated with infant negative affectivity, especially fearfulness and sadness—early emerging risk factors for internalizing difficulties such as anxiety. The aim of the current study was to investigate whether human milk cortisol is associated with mother‐reported fearfulness and experimentally induced infant fear reactivity. Mother‐infant dyads (n = 65) enrolled in the FinnBrain Cohort Study participated. Breast milk samples were obtained 2.5 months postpartum, and milk cortisol concentrations were ascertained using validated luminescence immunoassay methodology. Infant fear reactivity was assessed using maternal reports 6 months postpartum and in a laboratory 8 months postpartum. There was a significant interaction between infant sex and milk cortisol such that higher milk cortisol was related to higher infant fear reactivity in a laboratory setting in girls (β = 0.36, p = .04) but not in boys (β = ?0.15, p = .40). Milk cortisol was not associated with mother‐reported infant fearfulness. Results suggest that higher human milk cortisol concentrations are associated with elevated experimentally induced fear in infancy. Findings support lactocrine programming, and suggest that mothers may “communicate” vital information about stressful environments via cortisol contained in breast milk, shaping girls' early emotional reactivity.     

Deep and surface structure in children's sentence learning

Fifth-graders were asked to learn 32 syntactically varied, semantically unrelated sentences containing combinations of agentive, objective and instrumental case relations. Five learning trials, each followed by a noun-prompted recall test, were provided. Recall patterns indicated that variations in surface structure complexity (i.e., verb voice and sentential position of noun prompts) exerted less influence on Ss' memory for sentences than deep structures. Several trials were required for Ss to reproduce syntactic details accurately and many transformational errors were observed. Even then, children were unable to learn one syntactic form. Although patterns of recall were more consistent with deep structure predictions, results were not completely supportive of Fillmore's analysis of deep structure in terms of case relations, and the possibility that other non-linguistic means were used to store sentences loomed as an alternative to the deep structure view.     

Introducing a forced-choice recognition task to the California Verbal Learning Test – Children’s Version

The importance of performance validity tests (PVTs) is increasingly recognized in pediatric neuropsychology. To date, research has focused on investigating whether PVTs designed for adults function similarly in children. The downward extension of adult cutoffs is counter-intuitive considering the robust effect of age-related changes in basic cognitive skills in children and adolescents. The purpose of this study was to examine the signal detection properties of a forced-choice recognition trial (FCR-C) for the California Verbal Learning Test – Children’s Version. A total of 72 children aged 6–15 years (M = 11.1 , SD = 2.6) completed the FCR-C as part of a larger neuropsychological assessment battery. Cross-validation analyses revealed that the FCR-C had good signal detection performance against reference PVTs. The first level of failure (≤14/15) produced the best combination of overall sensitivity (.31) and specificity (.87). A more conservative FCR-C cutoff (≤13) resulted in a predictable trade-off between sensitivity (.15) and specificity (.94), but also a net loss in discriminant power. Lowering the cutoff to ≤12 resulted in a slight improvement in specificity (.97) but further deterioration in sensitivity (.14). These preliminary findings suggest that the FCR-C has the potential to become the newest addition to a growing arsenal of pediatric PVTs.     

Identification of Early Child and Family Risk Factors for Aggressive Victim Status in First Grade

This prospective investigation sought to discriminate children who were both aggressive towards and victimized by peers in the first grade, from those who were only aggressive, only victimized, or neither (i.e., socially adjusted), using early child and family risk factors. Two hundred thirty-eight children, their mothers, and teachers participated in a longitudinal study since birth. All three aggressor/victim subgroups showed greater temperamental dysregulation than the socially adjusted children, but only aggressive victims had significantly poorer social perception skills. Aggressive victims were distinguished from aggressors by greater exposure to maternal depression and from victims by lower levels of early inhibition, but they shared the experiences of negative family emotional expressiveness with aggressors and greater mother-child negativity with victims. The identification of early risk factors is crucial to prevention and early intervention efforts that have the potential to attenuate the long term emotional, social, and academic problems associated with aggressive victim status.     

Effects of rodent prefrontal lesions on object-based, visual scene memory

It has been suggested that certain prefrontal areas contribute to a neural circuit that mediates visual object memory. Using a successive go/no-go visual scene discrimination task, object-based long-term memory was assessed in two rodent prefrontal regions. Rewarded trials consisted of a standard scene of four toy objects placed over baited food wells. The objects and their locations composing the standard scene remained constant for the duration of the study. Trials in which one of the standard scene objects was replaced with a novel object were not rewarded. Following the establishment of a significant difference between latency to approach the rewarded standard scene compared to latency to approach non-rewarded scenes, quinolinic acid or control vehicle was infused into either the prelimbic and infralimbic cortices or the anterior cingulate cortex. Following a 1 week recovery period, subjects were retested. Animals with prelimbic/infralimbic cortex lesions displayed a profound and sustained deficit, whereas, animals with anterior cingulate cortex lesions showed a slight initial impairment but eventually recovered. Both lesion groups acquired a simple single object discrimination task as quickly as controls indicating that the deficits on the original scene discrimination task were not due to motivational, response inhibition, or perceptual problems.     

Teaching children to comprehend propositions conjoined by “before” and “after”

Three experiments were conducted to evaluate a language-training procedure in which preschool children (age 51 months) were given sentences evoking opposite interpretations of the same syntactic structures. The syntactic forms of interest were before/after sentences in which order of event mention reverses the order of event occurrence. It was known that precomprehenders would misinterpret reverse-order forms describing two arbitrarily sequenced events but not two logically sequenced events. The training procedure entailed presenting exemplars which expressed both kinds of events in alternating order so that the discrepancy in interpretations might be detected and corrected by the child. Results indicated that this procedure was effective. A third experiment showed that its success was not due simply to practice with logically sequenced exemplars. Performance patterns gave evidence for the role of interpretational strategies during the course of acquisition. Processes of cognitive disequilibrium and restructuring are offered to explain results although alternative explanations are not ruled out.     

Happiness and International Migration

In this paper, we consider the extent to which the aggregate happiness of a country affects the flow of people across its borders. We merge data from the World Values Survey, which produces happiness indices for 84 countries between 1981 and 2004, with three different migration datasets: emigration rates from the Organization for Economic Cooperation and Development, immigration rates from the U.S. Census, and net migration rates from the United Nations. We find that happiness has a U-shaped relationship with emigration rates: emigration rates fall in happiness for relatively unhappy countries, but rise for relatively happy countries. The U-shaped relationship also holds for migrant flows into the U.S. When analyzing net migration rates, we find that the reverse relationship exists. Net migration is associated with an increase in happiness for relatively unhappy countries, but after a threshold level of happiness, net migration is associated with a decrease in happiness. Our findings are robust to various empirical specifications and datasets.