GABA, glutamate, dopamine and serotonin transporters expression on forgetting

Notwithstanding several neurotransmission systems are frequently related to memory formation; forgetting process and neurotransmission systems or their transporters; the role of γ-aminobutyric acid (GAT1), glutamate (EACC1), dopamine (DAT) and serotonin (SERT) is poorly understood. Hence, in this paper western-blot analysis was used to evaluate expression of GAT1, EAAC1, DAT and SERT during forgetting in trained and untrained rats treated with the selective serotonin transporter inhibitor fluoxetine, the amnesic drug d-methamphetamine (METH) and fluoxetine plus METH. Transporters expression was determined in the hippocampus (HIP), prefrontal cortex (PFC) and striatum (STR). Results indicated that forgetting of Pavlovian/instrumental autoshaping was associated to up-regulation of GAT1 (PFC and HIP) and DAT (PFC) while SERT (HIP) was down-regulated; no-changes were observed in striatum. Methamphetamine administration did not affect forgetting at 216 h post-training but up-regulated hippocampal DAT and EACC, prefrontal cortex DAT and striatal GAT1 or EACC1. Fluoxetine alone prevented forgetting, which was associated to striatal GAT1 and hippocampal DAT up-regulation, but prefrontal cortex GAT1 down-regulation. Fluoxetine plus METH administration was also able to prevent forgetting, which was associated to hippocampal DAT, prefrontal cortex SERT and striatal GAT1, DAT or SERT up-regulation, but prefrontal cortex GAT1 down-regulation. Together these data show that forgetting provokes primarily hippocampal and prefrontal cortex transporters changes; forgetting represent a behavioral process hardly modifiable and its prevention could causes different transporters expression patterns.     

Representing part–whole relations in conceptual spaces

In this paper, we propose a cognitive semantic approach to represent part–whole relations. We base our proposal on the theory of conceptual spaces, focusing on prototypical structures in part–whole relations. Prototypical structures are not accounted for in traditional mereological formalisms. In our account, parts and wholes are represented in distinct conceptual spaces; parts are joined to form wholes in a structure space. The structure space allows systematic similarity judgments between wholes, taking into consideration shared parts and their configurations. A point in the structure space denotes a particular part structure; regions in the space represent different general types of part structures. We argue that the structural space can represent prototype effects: structural types are formed around typical arrangements of parts. We also show how structure space captures the variations in part structure of a given concept across different domains. In addition, we discuss how some taxonomies of part–whole relations can be understood within our framework.     

Interwoven stories: our path of creativity and poetry named the ecodialogue center

The history of organizations and collectives is something alive. It is a network of memories, actions, collaborations, dreams, encounters, and disconnections that live within each of its members. The EcoDialogue Center is an academic space of the University of Veracruz for promoting dialogue between disciplines. In this article we are presenting the stories, both personal and collective, and the values and ideals that create our Center. We are using this opportunity to reflect on the cultural, geographical, emotional, intellectual, and societal conditions that have allowed this innovative process within the rules and customs of a university.     

NMDA and muscarinic receptors of the nucleus accumbens have differential effects on taste memory formation

Animals recognize a taste cue as aversive when it has been associated with post-ingestive malaise; this associative learning is known as conditioned taste aversion (CTA). When an animal consumes a new taste and no negative consequences follow, it becomes recognized as a safe signal, leading to an increase in its consumption in subsequent presentations (attenuation of neophobia, AN). It has been shown that the nucleus accumbens (NAcc) has an important role in taste learning. To elucidate the involvement of N-methyl-D-aspartate (NMDA) and muscarinic receptors in the NAcc during safe and aversive taste memory formation, we administrated bilateral infusions of DL-2-amino-5-phosphonopentanoic acid (APV) or scopolamine in the NAcc shell or core respectively. Our results showed that pre-training injections of APV in the NAcc core and shell disrupted aversive but not safe taste memory formation, whereas pre-training injections of scopolamine in the NAcc shell, but not core, disrupted both CTA and AN. These results suggest that muscarinic receptors seem to be necessary for processing taste stimuli for either safe or aversive taste memory, whereas NMDA receptors are only involved in the aversive taste memory trace formation.     

The use of the effect size in JCR Spanish journals of psychology: from theory to fact

In 1999, Wilkinson and the Task Force on Statistical Inference published "Statistical Methods and Psychology: Guidelines and Explanation." The authors made several recommendations about how to improve the quality of Psychology research papers. One of these was to report some effect-size index in the results of the research. In 2001, the fifth edition of the Publication Manual of the American Psychological Association included this recommendation. In Spain, in 2003, scientific journals like Psicothema or the International Journal of Clinical and Health Psychology (IJCHP) published editorials and papers expressing the need to calculate the effect size in the research papers. The aim of this study is to determine whether the papers published from 2003 to 2008 in the four Spanish journals indexed in the Journal Citation Reports have reported some effect-size index of their results. The findings indicate that, in general, the followup of the norm has been scanty, though the evolution over the analyzed period is different depending on the journal.     

Facets of the linear ordering polytope: A unification for the fence family through weighted graphs

The binary choice polytope appeared in the investigation of the binary choice problem formulated by Guilbaud and Block and Marschak. It is nowadays known to be the same as the linear ordering polytope from operations research (as studied by Grötschel, Jünger and Reinelt).The central problem is to find facet-defining linear inequalities for the polytope. Fence inequalities constitute a prominent class of such inequalities (Cohen and Falmagne; Grötschel, Jünger and Reinelt). Two different generalizations exist for this class: the reinforced fence inequalities of Leung and Lee, and independently Suck, and the stability-critical fence inequalities of Koppen. Together with the fence inequalities, these inequalities form the fence family. Building on previous work on the biorder polytope by Christophe, Doignon and Fiorini, we provide a new class of inequalities which unifies all inequalities from the fence family. The proof is based on a projection of polytopes. The new class of facet-defining inequalities is related to a specific class of weighted graphs, whose definition relies on a curious extension of the stability number. We investigate this class of weighted graphs which generalize the stability-critical graphs.     

Reconstructing N: A New Approach to Measuring Emotional Sensitivity

Neuroticism (N) assesses emotional sensitivity or lability, but the construct is poorly defined and instruments used to assess N are marred by a number of psychometric shortcomings. Neuroticism is also described in an overtly pejorative way, with items keyed for themes reflecting low self-esteem, anxiety, and depression. The present paper presents a revised model based on a new questionnaire entitled the Emotional Sensitivity Scale (ESS). Using an innovative scenario technique to generate items, exploratory factor analysis of the responses of 242 participants yielded orthogonal dimensions for positive (other-oriented) and negative (self-centered) emotional sensitivity, and the structure was confirmed using confirmatory factor analysis. Validation studies showed that the ESS dimensions were related in systematic ways to related psychometric instruments and that, as predicted, participants scoring high on the positive dimension were better able to recognize displayed emotions. The new scale offers a basis for extending the research on emotional sensitivity using empirically discriminable positive and negative components.     

Rumination, Inhibition and Stress: The Construction of A New Scale for Assessing Emotional Style

Emotional rumination and inhibition were identified in the Emotion Control Questionnaire (ECQ—Roger and Nesshoever 1987; Roger and Najarian 1989) as two relatively independent dimensions of emotional style, and the two measures have subsequently been shown to be important moderator variables in a range of health and forensic settings. Two other dimensions that emerged in the ECQ, labelled aggression control and benign control, have been shown to form part of the extraversion constellation, and the present paper describes the construction and validation of a new scale focusing exclusively on rumination and inhibition. Revised and expanded item pools for the scales were subjected to exploratory and confirmatory factor analyses, which endorsed the two-factor structure. The new scales were validated concurrently against related scales in different samples, and were shown to be systematically related to two independent indices of health status.     

Psycholinguistic variables involved in concept recall from the successive presentation of features / Variables psicolingüísticas involucradas en la evocación de conceptos a partir de la presentación de atributos sucesivos

Abstract

The aim of this study was to analyse the psycholinguistic variables of the attributes and concepts involved in the recall of a concept. One hundred and twenty adults (18–40 years old) participated. A lexical recall task was administered by presenting a successive list of defining attributes. Forty concepts from different semantic categories were used. The attributes were obtained empirically from local Semantic Features Production Norms. The influence of the characteristics and attributes of the concepts on the number of participants who accessed the name of the concept and the correct guess trend was analysed. Significant values for Age of Acquisition, Presence of Distinctive Attributes and Presence of Taxonomic Attributes were observed. Results show that concepts which are acquired earliest are more easily recalled; presenting taxonomic categories narrows the search and the presence of distinctive attributes allow differentiating between such concepts within a category.     

The influence of decision task and deliberation style on the verdict of the juries

The influence of decision task and deliberation style on the verdict of the juries. In the Kameda's Deliberation Style Model the emission of verdicts of responsibility when the deliberation style of the juries (elemental/compound) and the type of decision task (disjunctive/conjunctive) are jointly manipulated, is favoured in certain conditions. Given the consequences that these approaches could have in real judicial processes, this model is analyzed using a manslaughter crime under the Spanish judicial context conditions (nine members juries and seven or five members majorities emitting a verdict of guilty or not guilty, respectively). The obtained results indicated a better operation of the model when a conjunctive decision task was demanded.