Strength of scopolamine-induced amnesia as a function of time between training and testing

Variations in the strength of scopolamine-induced amnesia as a function of age of the habit were studied in Swiss Webster mice. Animals were trained in an active avoidance task to a criterion of 9/10 avoidances and immediately following training injected with scopolamine hydrochloride (1.0 mg/kg) or saline. Retention of the avoidance learning was evaluated by testing different groups of animals 1, 3, 7, 10, 14, and 28 days following training. The retention test consisted of five trials in which the CS but not the UCS was presented. Results indicated that saline-treated mice exhibited near-perfect retention up to 14 days post-training with forgetting beginning to be apparent at 28 days. Scopolamine treatment produced strong amnesia in animals tested 1 and 3 days post-training but normal retention in animals tested 7 and 10 days after learning. The amnesia abruptly reappeared at 14 days after which time it remained stable. The marked similarity of the scopolamine retention curve to changes in the strength of memory of discrimination learning in undertrained rats reported by Deutsch suggested that scopolamine resulted in the storage of a weak memory of the avoidance response. To explore this idea further we trained mice to a criterion (4/5) which would result in a weak avoidance response and tested different groups 1, 3, 10, 14, and 28 days following learning. Results showed that strength of the memory of avoidance learning increased up to 10 days and then decreased abruptly at 14 days thus replicating the general shape of the retention curve produced by injecting scopolamine following strong training. These data suggest that scopolamine disrupts processes essential for the formation of durable memories.     

Classification of adult attachment: an integrative taxonomy from attachment and psychoanalytic theories.

Developmental and psychoanalytic theorists have focused increasingly on empirically determined early childhood antecedents of adult attachments, with several resulting taxonomic models. This article suggests a theoretically based and clinically based model of attachment consistent with both psychoanalytic and attachment theories, resulting in an integrative taxonomy of four adult attachment styles: dependent, avoidant, hostile, and resistant-ambivalent. These styles reflect behavioral manifestations of dependence and anger, as derived from the interaction of primitive relational drives, defenses, and interpersonal experience. In addition to theoretical construction, brief clinical examples are presented to facilitate discussion of the model.     

Conditional reflexes as related to hypnosis and hypnotic techniques

Hypnosis has never been adequately explained in terms of conceptual framework of most schools of psychotherapy. The psychoanalytic concept that it consists of submission and surrender of important ego functions to the therapist does not explain all observed facts. During my wartime studies and since, I have been impressed by the observation that the patient’s ego is by no means powerless and defenseless, even during a deep state of trance, i.e., in states of trance sufficiently deep to eliminate awareness of painful body injuries (1965). Erickson (1954) has shown on many occasions that in resistant subjects one of the best ways to induce trance is to encourage the patient to resist as much as he can. Haley (1963) has pointed out in detail that at the beginning of any hypnotic relationship there evolves a subtle battle for “one-upmanship.” These observations certainly show that surrender in the psychological sense is by no means an aspect of even the most successfully induced trance states.     

The wilderness therapy program: An empirical study of its effects with adolescents in an outpatient setting

The results of a study of the Wilderness Therapy Program involving 23 adolescents in outpatient counseling are presented. Data were collected before and after four trips on measures of locus of control, behavioral symptoms, self-efficacy, self-esteem, and a number of measures designed specifically for this program. Following a one and one-half to two week backpacking trip that included daily therapy, significant change was found for locus of control, self-esteem and symptom reduction. Positive changes were noted on the other measures as well. Future directions and social work implications were discussed.     

Information and Counseling: A Dilemma

The revolutionary changes in data processing, and the resulting increases in the quantity and quality of information about counselees and their prospective environments, will make the work of the counselor more difficult in several ways. The one problem that is highlighted is the difficulty of maintaining a true counseling process and relationship while at the same time collecting necessary information about the client and about the environments regarding which he must make decisions. 2 solutions and their relative merits are discussed, one involving separation of the information and counseling functions, and the other requiring an integration of the functions by a single counselor.     

We have a prejudice against ourselves—Sentiment,ethics, and reason

Briefly stated my point is that the well-being of each person in a community conceived abstractly may be all too easily sacrificed for the sake of the abstraction. Physicians may offer critically ill patients places in programs of experimental treatment, but there is commonly a catch to the offer. To take part in a program of clinical experiment a patient must not only risk a possible failure of a fresh drug and the chance of destructive side effects from the drug, but the patients must risk only getting the traditional treatment along with a placebo rather than the experimental drug. Placebo control, double blind critical protocols for testing effects of fresh drugs on critically ill patients are a commonplace. I question the scientific objectivity of the protocols and the underlying ethic, and suggest use of alternate protocols. Experimental tests in the treatment gram-negative bacteria blood infections, muscular dystrophy, and AIDS and AIDS-related diseases are examples.     

The effects of hormones,Type A behavior pattern,and provocation on aggression in men

Thirty-eight male college students, classified as either Type A or Type B based on their Jenkins Activity Survey (JAS-T) scores, competed in a reaction time task that allowed them to administer shocks to an increasingly provocative fictitious opponent. Salivary testosterone and cortisol were measured both prior to and after the task. Aggression was defined as the level of shock the subject was willing to set for the opponent. The results of this study indicate that a relationship exists between endogenous testosterone levels in men and direct physical aggression. Some evidence for the moderating effects of hormones on the level of aggression expressed by Type As was observed. No direct relationship between Type A and aggression was found.     

FACIAL EXPRESSION AND SPEECH: NEUROANATOMICAL CONSIDERATIONS

This paper discusses the neuroanatomy and pathology of facial expression and findings on the neuroanatomical connections between expressions of the face and speech. The facial musculature is briefly dealt with in terms of its innervation by the facial nerve and its relationship to the soft palate at the peripheral system level. After considering the facial nuclei, the supranuclear innervation of volitional and emotional facial expression is reviewed. Then supranuclear relations between facial movements and some speech organs are considered. Finally, attention is paid to aspects of facial paralysis stemming from peripheral and central origins.