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The gateway drug model is a popular conceptualization of a progression most substance-users are hypothesized to follow as they try different legal and illegal drugs. Most forms of the gateway hypothesis are that "softer" drugs lead to "harder," illicit drugs. However, the gateway hypothesis has been notably difficult to directly test - i.e., to test as competing hypotheses in a single model that licit drug use might lead to illicit drug use or the reverse. This article presents a novel statistical technique, dual-process discrete-time survival analysis, which enables this comparison. This method uses mixture-modeling software to estimate two concurrent time-to-event processes and their effects on each other. Using this method, support for the gateway hypothesis in the National Longitudinal Survey of Youth 1997 was weak. However, this paper was not designed as a strong test of causal direction but more as a technical demonstration, and suffered from certain technological limitations. Both these limitations and future directions are discussed.  相似文献   
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异体造血干细胞移植(Allo-HSCT)已成为治疗恶性血液病及其他各种疾病的有效方法之一。在Allo-HSCT中由于供体和受体免疫屏障的存在。从而一开始就是一个供受体矛盾的对立统一的过程。对其中矛盾的研究和解决充满了辩证唯物的哲学思想。也促使Allo-HSCT技术不断发展。新的方法和理念不断出现。使Allo-HSCT治疗白血病的疗效不断提高。  相似文献   
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从契此的“手把青苗插满田,低头便见水中天,六根清净方为道,退步原来是向前”偈中,反映了退让并不是完全的消极,有时反而是一种积极的进取,从而揭示出丰富的人生哲理。  相似文献   
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The relationship among alcohol-related problems, perceived burdensomeness, thwarted belongingness, and suicide proneness in undergraduate college students (N=996) was examined. As hypothesized, alcohol-related problems, perceived burdensomeness, and thwarted belongingness were all significantly and positively correlated with suicide proneness. The relation between experiencing alcohol-related problems and suicide proneness was, in part, accounted for by perceived burdensomeness and thwarted belongingness. Additionally, the mediation via perceived burdensomeness was significantly stronger than the mediation via thwarted belongingness. Results suggest that it would be advisable for clinicians to be aware of students' experiences with alcohol-related problems in conjunction with their levels of burdensomeness and belongingness when assessing for suicide risk.  相似文献   
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"多病则与学道者宜,多难则与学禅者宜",苏辙却因有"喜汝因病悟,或免终身著"的示疾而病的禅学思想。"示疾而病"的苏辙以维摩自喻,在深层意义上,是他借维摩诘而表现其忧以天下、以乐天下的人格理想。  相似文献   
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卫生是人类重要的社会实践活动。卫生也是保护人体健康的重要社会事业,需要法律的保护和导向。卫生法为卫生发展提供了良好的社会环境,并控制医药卫生无序、失控及异化带来的社会危害性,造福人类,促进经济发展和社会进步。  相似文献   
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The Universal Declaration of Human Rights is a general legislative framework for democratic societies. Studying the social representations of these basic human rights helps to explain how people understand and assess the basic rights and how these rights relate to everyday life. Over 400 Czech university students rated the 30 articles of the Declaration of Human Rights on various scales (degree of understanding, personal relevance, consequences for individual responsibility, for government, political parties, etc.). A semantic space was identified in which concepts (i.e. the Articles of the Declaration) could be located. A typology (clusters) of articles was then established within that semantic space. A factor analysis of the scales resulted in a two-dimensional solution (‘positive attitude’ and ‘personal influence’). Five clusters of assessed articles were identified within this semantic space. (© 1997 by John Wiley & Sons, Ltd.)  相似文献   
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This study explores culture's effect on behaviors and outcomes in intercultural negotiation and examines how those effects are moderated by role. Eighty U.S. and international students took part in a previously developed negotiation task (Pruitt, 1981) and completed Hui and Triandis's (1986) individualism‐collectivism (INDCOL) scale. Negotiation interactions were coded for information sharing, offers, and distributive tactics. Findings show that a negotiation dyad's collectivism is positively associated with higher joint profit. The effects of culture on both communication behaviors and joint outcomes, however, differ by role of the negotiator. In particular, seller collectivism has larger and more consistent effects on communication behavior and joint profit than buyer collectivism. Results support a ‘culture in context’ perspective of negotiation that takes into account negotiator qualities, contextual and structural features of the negotiation, and mediating processes in addition to cultural values.  相似文献   
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In this study, we examined estimates of internal consistency reliability, measurement invariance, and differential correlates of the Multidimensional Scale of Perceived Social Support (MSPSS; Zimet, Dahlem, Zimet, & Farley, 1988) in samples of undergraduate men (n = 270) and women (n = 340). The MSPSS is designed to assess 3 sources of perceived social support: family, friends, and significant others. The participants ranged in age from 18 to 24 years (M age = 19.60, SD = 1.4 years). First, composite scale reliability and coefficient omega methods provided adequate estimates of internal consistency reliability for the original MSPSS total and subscale scores. Second, results of multiple-groups invariance confirmatory factor analysis provided support for configural and metric invariance. Partial measurement invariance was attained for scalar and strict measurement invariance across men and women. Additionally, given the high correlations among the first-order factors, we conducted multiple-groups bifactor item response theory (bifactor-IRT) analysis to evaluate further the performances of the individual MSPSS items across gender. Support for the bifactor model was strong. Third, we conducted a series of simultaneous regression analyses to identify potential correlates of the social support construct for women and men.  相似文献   
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