Microdialysis administration of vasopressin and vasopressin antagonists into the septum during pole-jumping behavior in rats.

Wistar rats (n = 95) were trained in a pole-jumping apparatus (10 trials/session/day) to investigate the involvement of centrally and peripherally released endogenous AVP in their acquisition rate and to examine the feasibility of the microdialysis technique for the administration of peptides during a behavioral test. After session 1, a microdialysis probe was implanted into the septum; during sessions 2 and 3 the probe was perfused with artificial cerebrospinal fluid (aCSF) alone or containing either AVP (delivered amount via the probe: 0.2 ng) or the V1 (d(CH2)5Tyr(Me)AVP, 5.0 ng) or the V2/V1 (d(CH2)5-D-Tyr(Et)VAVP, 5.0 ng) antagonist. Administration of AVP via microdialysis into the septum failed to alter the acquisition rate of pole jumping. Also, ip application of both hypertonic saline and the AVP V1 antagonist (10 micrograms) in another experiment failed to show a significant effect upon behavior. Septal administration of the V1 or the V2/V1 antagonist via microdialysis, however, produced a significantly impaired performance. The results indicate that AVP release within the septum is involved in the acquisition of pole-jumping behavior probably mediated by the V1 receptor subtype. An additional involvement of the V2 receptor subtype, however, cannot be entirely excluded. The microdialysis technique proved to be a potent tool to administer substances concomitantly with behavioral tests.     

Intra- and interindividual relationships between elation-depression and desire for excitement

This study examined the relationship between elation-depression and desire for excitement on both intra- and interindividual levels. It was hypothesized that there would be a positive linear relationship between elation and desire for tranquillity These intraindividual hypotheses received strong support. This support would suggest that radical incongruities between activity demands and mood preparedness are often painful and would imply that in order for mood alteration to be successful it must take place gradually It was also hypothesized that characteristic level of elation-depression would be positively related to mean ratings of desire for excitement, positively related to score on a desire for excitement test, and negatively related to mean ratings of desire for tranquillity These interindividual hypotheses were not supported. Although it is probably most reasonable to accept the lack of correspondence between intra- and interindividual results, the operation of social comparison effects and social desirability bias may have obscured the predicted interindividual relationships     

An MMPI-based empirical model of malingering and deception

The empirically-based model of malingering and deception described by Rogers (1984b) was operationalized using MMPI and clinical interview data. Subjects (N = 159) were patients committed to an inpatient forensic hospital as ‘Incompetent to Stand Trial’ or ‘Not Guilty by Reason of Insanity’. Inter-rater reliability was acceptable for the 11 criteria used to define response styles. Each subject was categorized into one of five response style groups: ‘Reliable’, ‘Malingering’, ‘Defensive’, ‘Irrelevant’, or ‘Unclassifiable’. Factor analysis of the rating criteria yielded four factors, three of which are comparable to the assigned groups, providing some validation for the constructs underlying these groups.     

Programmed stuttering therapy for children: Comparison of four establishment programs

Four different establishment programs (programmed traditional, delayed auditory feedback, pause, and gradual increase in length and complexity of utterance) for improving the fluency of school-age children who stutter were compared. The programs were carried out by eight public school clinicians with 16 children (eight elementary and eight junior-senior high school) in their respective schools. All four programs produced important improvement in the speech fluency of the 16 children. All the children demonstrated transfer of fluency to extratraining settings. The delayed auditory feedback program required the least therapy hours, but it was difficult for the clinicians to operate correctly. The gradual increase in length and complexity of utterance programs produced the best overall results. The transfer and maintenance programs provided for additional generalization and permanency of fluency. Follow-up revealed that the children continued their increased level of fluency.     

Dimensions of perfectionism and irrational thinking

Several authors have suggested that perfectionism is associated with irrational thinking. The purpose of the present research was to test the hypothesis that various dimensions of perfectionism are related significantly to core irrational beliefs. In Study 1, 102 subjects completed the Multidimensional Perfectionism Scale (MPS) and the Irrational Beliefs Test (IBT). The MPS provides assessments of self-oriented, other-oriented, and socially prescribed perfectionism. Analyses revealed that self-oriented perfectionism was correlated positively with the IBT high self-expectations and perfect solutions subscales. Socially prescribed perfectionism was correlated significantly with a variety of irrational beliefs including high self-expectations, demand for social approval, dependency, blame proneness, and anxious overconcern. Other-oriented perfectionism was correlated with few irrational beliefs. In Study 2, 130 subjects completed the MPS and the Survey of Personal Beliefs, a new measure of core irrational beliefs. Analyses confirmed that all three perfectionism dimensions were associated with core irrational beliefs. It is concluded that the results constitute general support for the hypothesis that cognitive aspects are important in both personal and social components of perfectionism and that perfectionists are characterized by increased levels of irrational beliefs that may contribute to maladjustment. The findings are discussed in terms of the associations among perfectionism, irrational beliefs, and maladjustment.Gordon L. Flett, Ph.D is currently an assistant professor in the Department of Psychology at York University. Paul L. Hewitt, Ph.D is a clinical psychologist at Brockville Psychiatric Hospital. He is also an assistant professor in the Department of Psychiatry at the University of Ottawa. Kirk R. Blankstein, Ph.D, is an associate professor in the Department of Psychology at Erindale College, University of Toronto. Spomenka Koledin is a former student at Erindale College, University of Toronto. Currently, she is a graduate student in the Master of Arts programme at York University.     

Semantic categorization in a linear order problem

The present investigation was conducted to determine whether subjects could use categorical codes based on semantic memory information (gender of names) to make rapid decisions about the order of names in a linear series. Subjects were taught linear order problems in which 12 names (six male and six female) were either randomly ordered or blocked by sex. The results support a dual-process model which proposes that subjects use both categorical information (discrete linguistic codes) and serial position information when asked to make mental comparisons of arbitrarily ordered items. Furthermore, the data indicate that both the ordinal distance between the terms in the test pair (step size) and the serial position of the test terms in the linear order affect the reaction time to a particular test comparison.