The nature and treatment of stuttering as revealed by fMRI A within- and between-group comparison

This article reviews some of our recent functional magnetic resonance imaging (fMRI) studies of stuttering. Using event-related fMRI experiments, we investigated brain activation during speech production. Results of three studies comparing persons who stutter (PWS) and persons who do not stutter (PWNS) are outlined. Their findings point to a region in the right frontal operculum (RFO) that was consistently implicated in stuttering. During overt reading and before fluency shaping therapy, PWS showed higher and more distributed neuronal activation than PWNS. Immediately after therapy differential activations were even more distributed and left sided. They extended to frontal, temporal, and parietal regions, anterior cingulate, insula, and putamen. These over-activations were slightly reduced and again more right sided two years after therapy. Left frontal deactivations remained stable over two years of observation, and therefore possibly indicate a dysfunction. After therapy, we noted higher activations in persons who stutter moderately than in those who stutter severely. These activations might reflect patterns of compensation. We discuss why these findings suggest that fluency-inducing techniques might synchronize a disturbed signal transmission between auditory, speech motor planning, and motor areas.

Educational objectives: The reader will learn about and be able to: (1) identify regions of brain activations and deactivations specific for PWS; (2) describe brain activation changes induced by fluency shaping therapy; and (3) discuss the correlation between stuttering severity and brain activation.     

Fehldiagnose Aufmerksamkeitsdefizit- und Hyperaktivit?tssyndrom?

Although it is assumed both by healthcare professionals as well as by public opinion that attention deficit hyperactivity disorder (ADHD) is widely overdiagnosed, so far there is little empirical evidence to support this presumption. However, the presented study shows clear evidence for an overdiagnosis of ADHD. Furthermore, the data demonstrate that based on identical symptoms, boys more often receive a diagnosis for ADHD than girls. A false ADHD diagnosis also correlates with a recommendation for medical and psychotherapeutic treatment. One explanation for misdiagnosis is the fact that therapists in the course of diagnosis, as with other everyday decision-making processes, are influenced by heuristics. The most common heuristics that can lead to misdiagnosis are the representativeness heuristic and the availability heuristic. Such mistakes could be avoided by clearly following diagnostic criteria and the use of structural interviews.     

Architecture and organizational principles of Broca's region

Identifying cortical areas for language and speech processing is a prerequisite for cognitive neuroscience and clinical research. Although Broca's region is one of the essential nodes in the language network, its anatomical constituents are ill-defined and multiple definitions of Broca's region exist. Sanides' concept of microstructural gradations interpreted Broca's region as developing from neighboring motor, dorsolateral-prefrontal, and insular cortices. Recent mapping approaches based on cytoarchitecture, transmitter receptor distribution, and connectivity revealed a highly differentiated segregation of this region far beyond Brodmann's classical scheme. This novel segregational concept of structural and functional architecture more adequately reflects the various functions of Broca's region in cognitive and/or linguistic processes.     

Diagnosing fatigue in gait patterns by support vector machines and self-organizing maps

The aim of the study was to train and test support vector machines (SVM) and self-organizing maps (SOM) to correctly classify gait patterns before, during and after complete leg exhaustion by isokinetic leg exercises. Ground reaction forces were derived for 18 gait cycles on 9 adult participants. Immediately before the trials 7–12, participants were required to completely exhaust their calves with the aid of additional weights (44.4 ± 8.8 kg). Data were analyzed using: (a) the time courses directly and (b) only the deviations from each individual’s calculated average gait pattern. On an inter-individual level the person recognition of the gait patterns was 100% realizable. Fatigue recognition was also highly probable at 98.1%. Additionally, applied SOMs allowed an alternative visualization of the development of fatigue in the gait patterns over the progressive fatiguing exercise regimen.     

Developing a Concept of Muslim Religiosity: An Analysis of Everyday Lived Religion among Female Migrants in Austria

In this article, we generate a concept of Muslim religiosity based on narrations reflecting Muslim women’s everyday lived religion in Austria. Using Grounded Theory, we analysed 30 biographical interviews conducted in 2006 with first-generation female migrants from Turkey and Bosnia-Herzegovina. In agreement with prior studies, we emphasise that Muslim religiosity is multi-dimensional. According to our results, it consists of a belief and a behavioural dimension, with the latter dividing into ‘rituals and duties’ and ‘ethical behavioural principles’. Moreover, we pay close attention to the interrelation between religion and culture—which is particularly relevant in a migration context—and shed light on the functions of religiosity.     

Retest effects in working memory capacity tests: A meta-analysis

The repeated administration of working memory capacity tests is common in clinical and research settings. For cognitive ability tests and different neuropsychological tests, meta-analyses have shown that they are prone to retest effects, which have to be accounted for when interpreting retest scores. Using a multilevel approach, this meta-analysis aims at showing the reproducibility of retest effects in working memory capacity tests for up to seven test administrations, and examines the impact of the length of the test-retest interval, test modality, equivalence of test forms and participant age on the size of retest effects. Furthermore, it is assessed whether the size of retest effects depends on the test paradigm. An extensive literature search revealed 234 effect sizes from 95 samples and 68 studies, in which healthy participants between 12 and 70 years repeatedly performed a working memory capacity test. Results yield a weighted average of g =?0.28 for retest effects from the first to the second test administration, and a significant increase in effect sizes was observed up to the fourth test administration. The length of the test-retest interval and publication year were found to moderate the size of retest effects. Retest effects differed between the paradigms of working memory capacity tests. These findings call for the development and use of appropriate experimental or statistical methods to address retest effects in working memory capacity tests.     

Subjective,physiological, and behavioural responses towards evaluatively conditioned stimuli

Evaluative Conditioning (EC) is commonly defined as the change in liking of a stimulus (conditioned stimulus, CS) due to its pairings with an affective unconditioned stimulus (US). In Experiment 1, we investigated effects of repeated stimulus pairings on affective responses, i.e. valence and arousal ratings, pupil size, and duration estimation. After repeatedly pairing the CSs with affective USs, a consistent pattern of affective responses emerged: The CS_negative was rated as being more negative and more arousing, resulted in larger pupils, and was temporally overestimated compared to the CS_neutral. In Experiment 2, the influence of a mere instruction about the contingency between a CS and US on affective responses was examined. After mere instruction about upcoming pairings between the CS and US, subjective ratings also changed, but there was neither evidence for differential pupillary responses nor for differential temporal processing. The results indicate that EC via pairings or instructions can change the affective responses towards formerly neutral stimuli and introduce pupil size as a physiological measure in EC research. However, Experiment 2 suggests that there might be moderating factors based on the type of EC procedure involved.     

Humour as the Playful Sidekick to Language in the Zhuangzi

Humour in the Zhuangzi is used to question the priority that human beings bestow upon language and thought, revealing both its limitations and its possibilities. Hierarchies and conventions are overturned and both the sense and senselessness of language are celebrated. Humour also opens up a world in which a plethora of perspectives is acknowledged and the purpose of purposelessness is underscored. Encouraging us to take laughter seriously also allows us to view the seeming gravity of the human condition with increased levity.     

The Twisted Relationship Between School Spending and Academic Outputs: in Search of a New Metaphor

In this commentary we explore both putative and potential relationships between school funding and educational outcomes, for which numerous indices and variables have been examined during the past two decades. We conclude that despite large increases in real dollars, there is no readily discernable link between inputs and outputs, although when statistical control is exerted over prior ability, school mix, and teacher turn-over, certain causal inferences appear warranted. However, it can be argued that the dominant analogy should be reconsidered, and schools serving large numbers of needy children may require higher inputs to keep from further declines, much like certain departments of a hospital require disproportionately more resources than others in order to be successful because they deal with problems that are more severe.