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Nitric oxide (NO) is synthesized as a result of N-methyl-d-asparate (NMDA) receptor activation, it acts as an retrograde neurotransmitter freely diffusing across cell membranes interacting with its targets in a non-synaptic manner. Consequently, NO has been described as an extension of NMDA receptor activation. The targets of NO include cellular components within the basolateral complex of the amygdala (BLA) that are necessary for the consolidation of conditioned fear as well as targets that can significantly modulate neurotransmission associated with its expression. Given that both are NMDA receptor associated processes, this implies that NO may be an important intermediary of NMDA receptor activation and both fear memory consolidation and expression. The current study sought to examine this using visual fear conditioning and fear potentiated startle. Three experiments were conducted, rats received intra-BLA microinfusions of the global nitric oxide synthase inhibitor l-NAME either prior to fear conditioning, or expression of learned fear. Furthermore, NO's ability to modulate a NMDA receptor independent fear process was assessed by microinfusing l-NAME into the BLA prior to examination of the shock sensitization of the acoustic startle affect. The results indicated that NO was, indeed, required for both the consolidation and expression of learned fear, whereas it was not required for NMDA independent shock enhanced startle responding. This study illustrates that NO plays a pivotal role in the examined NMDA associated fear processes.  相似文献   
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Context: The challenge of producing ethical representational practices is of critical interest to both practitioner‐researchers and research theorists. For practitioners becoming researchers a central ethical question may be how to manage a relational presence in writing their research, in ways that acknowledge participants, the research relationship, and a researcher's own subjectivity. Focus: The article offers examples from practitioner research to illustrate and theorise how researcher subjectivity is managed through the use of witnessing practices as a representational strategy. Witnessing practices – translated into counselling research from narrative therapy – offer researchers a strategy to take up a reflexive, relational presence in research reports. Discussion: Researcher witnessing honours the contributions of research participants as well as making visible the shaping effects of the research on a researcher's life. Through witnessing self and other, and thus declaring presence, privilege and partiality, re‐presentational ethics are made transparent.  相似文献   
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There are strong social pressures for U.S. females, particularly those of European heritage, to achieve and maintain an extremely low body weight. These pressures are reflected in a variety of media sources, including advertising. We argue that valuing thinness, exposure to thinness-depicting media, and lacking skepticism about tobacco advertisements have adverse effects on young women's decisions about smoking, particularly smoking for weight control. We tested these hypotheses in a study of 188 female undergraduates, both never-smokers and daily smokers. Believing that smoking controls weight, exposure to thinness-depicting media, and low levels of skepticism about tobacco advertising were associated with being a smoker. Among smokers, believing that smoking controls weight, internalizing thinness pressures, and low levels of feminist consciousness were associated with smoking for weight control. Results are discussed with the aim of encouraging public health anti-smoking campaigns targeted at women, and smoking cessation programs that are responsive to the needs of weight-concerned female smokers.  相似文献   
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Schools in liberal democratic societies face a dilemma. On the one hand their role is to prepare students to make rationally autonomous choices, within prescribed limits, as to what kind of good life they will pursue. On the other hand, liberal democratic societies depend on common adherence to liberal democratic values, such as respect for truth, fairness and social justice, and schools need to teach these values. If schools are to include the teaching of such values among their aims, how should they assess them? The assessment of values is problematical for liberal democrats. School educators are willing and able to assess students' knowledge and skills (i.e. what students know and can do) but to assess their values implies that students are being assessed for what they are and this offends against a deeply ingrained belief that all persons in a liberal democracy have an intrinsic worth. This article will explore the problem of the assessment of values with particular reference to schooling in Australia.  相似文献   
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One hundred-thirty-nine women participated in this longitudinal study from the third trimester of pregnancy through 8-months postpartum. Women completed depression scales at several time points and rated their infant's characteristics and childcare stress at 2- and 6-months postpartum. Mothers' reports of infant temperament were significantly different for depressed and non-depressed mothers, with depressed mothers reporting more difficult infants at both measurement points. These differences remained after controlling for histories of maternal abuse or prenatal anxiety, which occurred more often in the depressed mothers. There were no significant differences in childcare stress or perceived support between the groups. Infant temperament and childcare stress did not change over time. Recommendations for practice include consistent ongoing evaluations of the "goodness of fit" within the dyad and exploring interventions for depressed mothers that provide guidance about interactions with their infants and the appropriateness of the infant behaviors.  相似文献   
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We used discrete choice conjoint analysis to model the ways 645 children’s mental health (CMH) professionals preferred to provide information to parents seeking CMH services. Participants completed 20 choice tasks presenting experimentally varied combinations of the study’s 14 4-level CMH information transfer attributes. Latent class analysis revealed three segments. Open Access professionals (32.2%) preferred that intake workers automatically provide all parents with CMH information. They preferred information prepared by professional organizations and located at accessible settings such as public schools. They responded favorably to the internet as a source of information for parents. Controlled Access professionals (22.2%) preferred information that was approved and recommended by a child’s therapist, prepared by an experienced clinician, and located at hospitals and CMH clinics. Process Sensitive professionals (45.6%) showed a stronger preference for active learning materials with parenting groups and therapist “coaching” calls supporting the knowledge transfer process. Simulations suggested that realizing the benefits of CMH information requires the development of knowledge transfer strategies that align the preferences of professionals with those of the families they serve.  相似文献   
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A system is described which simulates some of the visual rearrangements and changes in sensorimotor relations that occur when experimental subjects move their eyes while looking through a contact lens with a prism attached. The simulated system is more convenient than a system based on the use of a contact lens, and it is based on measures of eye movement that are important in research on the perceptual effects of visual rearrangement. The effects that occur are reviewed in this paper. We also show in detail how the artificial system, which has an eye movement monitor interfaced with a computer and display, simulates the former effects. The data show that experimental subjects who experience visual rearrangement by simulated means manifest the same kind of perceptual adaptation produced in studies in which visual rearrangement is generated by means of a prism mounted on a contact lens.  相似文献   
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VRS is a system of separate routines programmed to perform one or more of the functions for mapping neuronal receptive fields and determining neuronal response characteristics. The organization and use of the programming system are described along with the details of the routines.  相似文献   
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