Effect of chronic cold stress on intestinal epithelial cell proliferation and inflammation in rats

The present study evaluated the effect of chronic cold stress on intestinal epithelial cell proliferation and inflammation. Male Wistar rats were subjected to cold exposure for three weeks. At the end of the cold exposure, intestinal cell proliferation, luminal nitrite and protein levels, intestinal myeloperoxidase activity and mast cell numbers were evaluated. Severely compromised proliferation rate of the crypt-base cells was observed under chronic stress conditions. Cells isolated from stressed rats showed a decreased DNA content in villus and lower villus cell fractions and an increased DNA content in the crypt cells, as compared to controls. Chronic cold stress resulted in increased luminal nitrite, luminal protein levels, and intestinal myeloperoxidase activity. The number of mast cells was significantly elevated under chronic stress conditions. Chronic cold stress resulted in a compromised intestinal epithelial cell proliferation rate and induced inflammation in the rat small intestine, through the combined action of nitric oxide, neutrophils and mast cells.     

Spousal similarity in depression: a dyadic latent panel analysis of the panel study of Belgian households

Dyadic latent panel analysis (DLPA) was applied to eight waves of the Panel Study of Belgium Households (N = 954 couples). DLPA decomposes the observed variance of both members of a dyad into variance due to stable factors, factors that gradually change over time, and occasion-specific factors including random error. Total observed similarity between members of a dyad on one occasion is decomposed into stable similarity, similarity in factors that change over time, and occasion-specific similarity. The results show that depressive symptoms are influenced by stable and changing factors and that spousal similarity in both factors contribute to spousal similarity in depression on a single occasion. Spousal similarity in factors that change gradually over time suggests that shared-environmental factors contribute to depressive symptoms.     

Conventions,morals and strategy: Greta’s dilemma and the incarceration game

Synthese - I articulate the question of the value of common knowledge, or the question of why common knowledge is preferred to mere widespread knowledge. I argue that common knowledge often enjoys...     

Comparison of tongue muscle characteristics of preterm and full term infants during nutritive and nonnutritive sucking

Background

Independent oral feeding requires coordination of suck, swallow and breathe and the lingual musculature plays a significant role in this coordinative action. However, clinical benchmarks of lingual function fundamental to successful feeding have not been explored.

Aims

The present study tests our model for quantifying infant lingual force and size and compares the muscle measures of interest in two cohorts: healthy full-term infants (FT) (N = 5) and healthy preterm infants (PT) (N = 6).

Method

Using an instrumented pacifier and bottle nipple, we determined the resultant compressive forces applied to the nipple by the tongue during nutritive (NS) and nonnutritive sucking (NNS). Muscle size was estimated from measures of posterior tongue thickness using ultrasonography.

Results

After controlling for weight and post menstrual age, statistically significant differences were found between FT and PT infants beginning to feed for NNS frequency and NS tongue force. Clinically significant differences were detected for NNS tongue force and posterior tongue thickness. Additionally, PT infants demonstrated a significant difference in mean tongue force between NS and NNS and FT infants did not. FT infants demonstrated a significant difference in mean frequency between NS and NNS and PT infants did not. Linear regression indicated that mean posterior tongue thickness alone predicted 55% of the variance in NS force.

Conclusions

Results demonstrate the feasibility of our approach and suggest that infant tongue muscle characteristics necessary for successful feeding differ between healthy full term infants and preterm infants who are beginning oral feeding.     

When Good Consumers Turn Bad: Psychological Contract Breach in Committed Brand Relationships

To better understand the conditions under which committed consumers continue to support their preferred brand after a transgression versus turn against the brand and the underlying theoretical process, we study the interplay between brand commitment and specific types of transgressions. Across three scenario‐based and field studies, we show that consumers have psychological contracts with brands, which dictate the terms of the relationship, and for committed consumers, violations of any aspect in (out of) the contract results in a negative (indifferent) response. Furthermore, we demonstrate that consumer trust is the underlying mechanism: committed consumers exhibit more negative responses to in‐contract transgressions as a result of their lower trust in the brand.     

Sb 2 Te 3 and In 0.2 Sb 1.8 Te 3 : A comparative study of thermoelectric and related properties

Sb 2 Te 3 and its solid solutions with group III elements such as In are materials of current interest for their potential thermoelectric applications. Single crystals of Sb 2 Te 3 and In 0.2 Sb 1.8 Te 3 have been grown by the Bridgman method and their powder X-ray diffractograms obtained and indexed. The transport properties, namely electrical conductivity, Seebeck coefficient and thermal conductivity, as well as the optical bandgap of the alloys have been measured and are compared. The ternary alloy containing In has a smaller optical bandgap and lower electrical and thermal conductivity than Sb 2 Te 3, but a higher Seebeck coefficient.     

Trading Sex for Money or Compensation: Prevalence and Associated Characteristics from a Sexually Transmitted Infection (STI) Clinic Sample

The purpose of this study was to determine the prevalence and individual risk factors of people who trade or sell sex among sexually active individuals seeking HIV and sexually transmitted infection (STI) testing. Using electronic agency records, an analysis of the characteristics of 5,029 youth and adults who voluntarily obtained HIV and STI testing was conducted. Multiple imputation procedures for missing data from 3 variables and logistic regression were conducted. A total of 128 individuals reported having traded sex. Nine variables had statistically significant associations with trading sex. Individuals who identified as White and female had lesser odds of trading sex, whereas individuals who were transgender, were living in a shelter, had been sexually assaulted, had a previous STI, had high-risk sex, or used drugs had greater odds of trading sex. Elevated levels of high-risk behavior in addition to sexual trauma should be considered in intervention research and community health practice. Implications for service providers and researchers are discussed.     

Analyzing Big-Five Personality Traits of Indian Celebrities Using Online Social Media

Personality traits analysis has been an active area of research in information systems and its cognate disciplines. However, there are multiple challenges faced by questionnaire-based measurement of personality traits including low response rate and limited access to the individuals. This research paper presents a social media-based approach to determine the Big-Five personality traits of different groups of celebrities. First, authors collected the Twitter posts of celebrities in different professions and used IBM’s Watson Personality Insights tool to determine the personalities of these celebrities. Next, with the help of statistical analysis and visualization techniques, authors determined the personality pattern within and across the group of celebrities. The results demonstrate that there is significant difference across groups of celebrities on three of the Big-Five personality traits—Openness, Agreeableness, and Extraversion. However, there is no significant difference among the celebrity groups on the Conscientiousness and Neuroticism trait.     

Gambling, health and age: data from the National Epidemiologic Survey on Alcohol and Related Conditions.

The health effects of recreational gambling are presently unclear, particularly across age groups. Theories of healthy aging suggest that social activities, including gambling, may be beneficial to the health of older adults. Using cross-sectional data from the National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093), the authors examined associations between gambling (categorized as nongambling, recreational gambling, or problem/pathological gambling) and health and functioning measures stratified by age (40-64 years and >/=65). Problem/pathological gambling was uniformly associated with poorer health measures among both younger and older adults. Among younger respondents, poorer health measures were also found among recreational gamblers. However, among older respondents, recreational gambling was associated not only with some negative measures (e.g., obesity) but also with some positive measures (e.g., better physical and mental functioning). Longitudinal studies are needed to clarify the relationship between gambling and health in older adults in the context of healthy aging.     

The utility of the AusEd driving simulator in the clinical assessment of driver fatigue

Several driving simulators have been developed which range in complexity from PC based driving tasks to advanced "real world" simulators. The AusEd driving simulator is a PC based task, which was designed to be conducive to and test for driver fatigue. This paper describes the AusEd driving simulator in detail, including the technical requirements, hardware, screen and file outputs, and analysis software. Some aspects of the test are standardized, while others can be modified to suit the experimental situation. The AusEd driving simulator is sensitive to performance decrement from driver fatigue in the laboratory setting, potentially making it useful as a laboratory or office based test for driver fatigue risk management. However, more research is still needed to correlate laboratory based simulator performance with real world driving performance and outcomes.