Developing an efficient clinical information system for a comprehensive psychiatric institute: I. Principles,design, and organization

The principles, design considerations, and components of a clinical information system intended to support and enhance the patient care, educational, and research missions of a comprehensive psychiatric institute are presented. Major characteristics of the system are its emphases on efficiency, simplicity, and intensive user involvement throughout the development of the system.     

Intrusion patterns in rapid serial visual presentation tasks with two response dimensions

A rapid serial visual presentation (RSVP) paradigm using both one and two response dimensions was used to test parallel processing models of stimulus dimensions. Fifty subjects were asked to report the identity and/or color of a target uppercase word inserted in a series of lowercase words. The results produced a predominance of posttarget intrusions for color responses and a predominance of pretarget intrusions for identity responses. The requirement of a response to a second dimension impaired hit rates but did not change the pattern of intrusions. An examination of the distributions of intrusions in each response dimension as a function of the response given to the other dimension showed an unexpectedly high percentage of simultaneous hits, a moderate covariation between both responses, and the same patterns of intrusions when compared with the general distributions. While these results seem to be compatible with parallel models of processing for stimulus dimensions, two modifications to this model are suggested. First, the processing of response dimension(s) needs some attentional resources. Second, provision for a mixed model is indicated, which would include trials where no illusory conjunctions are formed.     

Neighborhood frequency effects and letter visibility in visual word recognition

Two experiments are described that measured lexical decision latencies and errors to five-letter French words with a single higher frequency orthographic neighbor and control words with no higher frequency neighbors. The higher frequency neighbor differed from the stimulus word by either the second letter (e.g.,astre-autre) or the fourth letter (chope-chose). Neighborhood frequency effects were found to interact with this factor, and significant interference was observed only tochope-type words. The effects of neighborhood frequency were also found to interact with the position of initial fixation in the stimulus word (either the second letter or the fourth letter). Interference was greatly reduced when the initial fixation was on the critical disambiguating letter (i.e., the letterp inchope). Moreover, word recognition was improved when subjects initially fixated the second letter relative to when they initially fixated the fourth letter of a five-letter word, but this second-letter advantage practically disappeared when the stimulus differed from a more frequent word by its fourth letter. The results are interpreted in terms of the interaction between visual and lexical factors in visual word recognition.     

Phoneme monitoring and lexical processing: Evidence for associative context effects

In this paper, we propose a new version of the phoneme monitoring task that is well-suited for the study of lexical processing. The generalized phoneme monitoring (GPM) task, in which subjects detect target phonemes appearing anywhere in the test words, was shown to be sensitive to associative context effects. In Experiment 1, using the standard phoneme monitoring procedure in which subjects detect only word-initial targets, no effect of associative context was obtained. In contrast, clear context effects were observed in Experiment 2, which used the GPM task. Subjects responded faster to word-initial and word-medial targets when the target-bearing words were preceded by an associatively related word than when preceded by an unrelated one. The differential effect of context in the two versions of the phoneme monitoring task was interpreted with reference to task demands and their role in directing selective attention. Experiment 3 showed that the size of the context effect was unaffected by the proportion of related words in the experiment, suggesting that the observed effects were not due to subject strategies.     

Response to commentaries on “A neurobiological model for near-death experiences”

This work has received financial support from FONDECYT (Project 1111-88). The authors also acknowledge the helpful comments of Dr. Bruce Cassels.     

Michel de Certeau's keys of political discernment in May 1968: The theological-spiritual assumptions that informed his tools of analysis

This article seeks to identify the theoretical tools that supported Michel de Certeau's political discernment during the crisis of May 1968 in France. De Certeau's ability to elucidate the novelty and complexity of this event is linked to the intertwining of his experiences as a historian, traveller (voyageur), and Christian (specifically a Jesuit). De Certeau's articulation of a 'theology of difference' allowed him to construct the intellectual and spiritual tools that enabled a lucid discernment of May 1968. Through this theology, derived from negative theology, de Certeau made the experience of faith operative at a moment of cultural crisis. The article also analyses possibilities involved in the ‘rupture’, that is, the fracture that is implied in modernity; in the notion of an event that highlights the deficiency of language, its incapacity to establish ‘a truthful communication’ in society; and the recognition of the poetic dimension of speech, which is capable of interweaving speech and action. The May 1968 event invites these elements mutually to redefine themselves.     

自闭症谱系障碍社交动机理论：机制及干预探索

自闭症谱系障碍(Autism Spectrum Disorder, ASD)表现为社会交往困难以及重复刻板兴趣或行为。社交动机理论提出ASD个体是由于社交动机缺乏导致的社交障碍。目前该理论缺乏理论元素及结构关系的系统论证, 及基于此理论的低龄ASD儿童群体的研究证据。本研究拟采用心理实验法、眼动及近红外脑成像技术, 探索低龄ASD儿童早期社交奖赏、社交定向异常眼动标记及眶额叶脑区活动的神经机制。此外, 通过音乐奖赏强化学习的干预方式改善该理论的核心元素(社交奖赏), 观测能否改善ASD儿童的社交动机。本研究的开展有望对该理论进行系统验证, 并形成改善社交行为的潜在干预方案。