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The current study was conducted to determine the potential relationship between stress-induced corticosterone secretion and corticosteroid receptor mRNA levels after 5 days of intermittent stress. In particular, we were interested in the rate at which animals terminate a stress response, and how this termination may be altered by repeated stress. Adult male Sprague-Dawley rats were subjected to either 5 days of restraint stress or 5 days of an unpredictable stress paradigm. Restraint-stress induced corticosterone secretion was measured on Days 1 and 5 in both groups, and animals were killed on Day 6. Glucocorticoid receptor (GR), and mineralocorticoid (MR) mRNA levels were determined using in-situ hybridization techniques. Five days of restraint stress caused an habituation of the plasma corticosterone response to stress measured 60 and 90 min post-stress initiation; this pattern of corticosterone secretion was not observed in the animals subjected to unpredictable stress. Five days of either stress paradigm did not alter MR mRNA levels measured within the hippocampus or GR mRNA levels within the hippocampus or the medial parvocellular division of the paraventricular nucleus of the hypothalamus (mpPVN). However, an individual's GR mRNA levels measured within the CA1/2 region of the hippocampus and the mpPVN were significantly correlated with the degree of habituation of the corticosterone response to stress measured on Day 5. This suggests that an increase in the rate of termination of the stress response and levels of GR within the hippocampus and mpPVN may be functionally related.  相似文献   
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In order to examine the potential of constructive thought strategies for enhancing employee job satisfaction, an existing dispositional model of job satisfaction was expanded and tested. Structural equation modeling techniques indicated significant relationships among constructive thought strategies, dysfunctional thought processes, subjective well-being, and job satisfaction. In addition, two competing models were examined to test for the full or partial mediation of the effects of constructive thought strategies on job satisfaction. The implications of these findings for constructive thought strategy training interventions are discussed, along with directions for future research efforts.  相似文献   
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This study tested the hypothesis that assertive and nonassertive people have different personality profiles and self-actualizing values. Results indicated that assertive and nonassertive groups differed significantly, in terms of their personality profiles based on the Personality Research Form, and their self-actualization profiles based on the Personal Orientation Inventory, supporting the tested hypothesis.  相似文献   
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