Effects of Acute Stress or Centrally Injected Interleukin-1beta on Neuropeptide Expression in the Immune System

Acute stress stimulates the expression and release of corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, and the pro-opiomelanocortin products beta-endorphin and ACTH from the anterior pituitary. These neuropeptides are also expressed in immune tissues, and it has been proposed that they may modulate immune responses to stress through paracrine mechanisms. We subjected rats to restraint stress or central injection of interleukin (IL)-1beta to determine whether these acute stimuli can alter the expression of neuropeptides in the spleen and thymus. Restraint stress significantly increased the contents of all these neuropeptides in thymic, but not splenic, extracts. A single icv injection of IL-1beta increased contents of CRH, AVP, ACTH and beta-endorphin in the spleens of both sham-operated and adrenalectomised (ADX) rats. IL-1beta increased thymic contents of CRH and ACTH in sham-operated rats but these increases were not observed in ADX rats. These results suggest that the effects of IL-1beta on neuropeptide expression in the spleen are independent of glucocorticoids, whereas IL-1beta stimulation of neuropeptide expression in the thymus is dependent on circulating glucocorticoids. There were significant correlations between increases in CRH, ACTH and beta-endorphin in the spleen, and between CRH and ACTH in the thymus, consistent with the suggestion that IL-1beta-induced increases in ACTH and beta-endorphin may be mediated through CRH. These results provide evidence that stressors can directly influence neuropeptide expression in immune tissues. Thus stress may influence immune functions through paracrine mechanisms involving locally synthesised neuropeptides as well as through activation of the hypothalamo-pituitary-adrenal axis.     

Attention and perceptual priming in the perceptual identification task

Prior research indicates that manipulations of attention during encoding sometimes affect perceptual implicit memory. Two hypotheses were investigated. One proposes that manipulations of attention affect perceptual priming only to the extent that they disrupt stimulus identification. The other attributes reduced priming to the disruptive effects of distractor selection. The role of attention was investigated with a variant of the Stroop task in which participants either read words, identified their color, or did both. Identifying the color reduced priming even when the word was also overtly identified. This result held regardless of whether color and word were presented as a single object (Experiments 1 and 2) or as separate objects (Experiment 4). When participants read and identified a color, the overt order of the responses did not matter; both conditions reduced priming relative to reading alone (Experiment 3). The results provide evidence against the stimulus-identification account but are consistent with the distractor-selection hypothesis.     

Tracking conversational repetition: an evaluation of target monitoring ability

The ability to track who one tells information to (target monitoring) is evaluated in the present study. Participants shared personal information with target persons across four sessions spaced one day apart, and were instructed not to duplicate information to the same person over successive conversations. Target monitoring success was evaluated both on‐line, during the information sharing sessions, and retrospectively, following the final session. On‐line monitoring, or avoiding telling someone what you told them before, was very good with only one prior shared fact (Sessions 2 and 3), but declined with two prior shared facts (Session 4). Retrospective monitoring, or remembering prior fact‐to‐person assignments, was most accurate for Session 1, but dropped off sharply for Session 2 and remained constant through Session 4. Temporal errors in retrospective fact‐to‐person assignment tend to shift forward in days (telescoping). Further research is needed on the complex interrelationship of source and target information exchanges. Copyright © 2006 John Wiley & Sons, Ltd.     

The structuring of identity among midlife women as a function of their degree of involvement in employment

The place of employment and the diversity of its relations to other roles within the life structure of midlife women were investigated. Three groups were compared: Group I (n = 44) had a continuous low level of involvement in employment from their early 20s to their early 40s; Group II (n = 20) changed from low to high involvement; and Group III (n = 32) maintained a continuous high level of involvement. Retrospective reports regarding subjects' commitment to a number of different roles and feelings during their early 30s and early 40s constituted the data. Findings indicated that: (1) women in Group I had a positive, confident view of their involvement in the traditional roles of mother, wife, and volunteer; (2) women in Group II, initially quite similar to those in Group I, restructured their role commitments by substituting involvement in employment for more traditional pursuits; and (3) women in Group III successfully integrated involvement in the multiple roles of worker, mother, wife, and volunteer. Implications for a more dynamic view of identity, which takes into account significant reorganization of the life structure after adolescence and variability among diverse groups of women, are discussed.     

A critical examination of the concept of gender

Although psychologists have become increasingly interested in such areas as sex differences, gender identity, and sex roles, the concept of gender remains ill defined. We undertake a critical review of this concept and try to show that (a) if the term gender is taken to refer to a set of biological and psychological variables which are related to one another in a complex way, and (b) if gender differences are treated as differences in degree and not in kind, then the concept of gender can be used in a meaningful way to make sense of the things we observe about people.This article is based in part on a symposium entitled Psychosexual Development and the Nature of Androgyny presented at the annual meeting of the Association for Women in Psychology, Pittsburgh, March 1978. Since both authors contributed equally to the conceptualization and writing of this paper, the order of authorship was determined by the toss of a coin. The authors would like to thank James Laird, Dennis Wixon, and Roger Bibace, Clark University, who read and commented on an earlier draft of this paper, and several anonymous reviewers whose comments helped us to clarify our presentation.     

Willingness to Help a Stranger: The Effects of Social Context and Opinion Similarity1

Two field experiments investigate how information about aspects of the social environment affects willingness to help others who are similar or dissimilar. Subjects were pedestrians who found a lost packet of materials containing information about the opinions of the packet's loser and a survey report which claimed that the quality of life in the neighborhood had either improved or deteriorated. In the fiist study, the opinions were varied in order to create different degrees of opinion similarity between the loser and subject. Results showed that relatively slight differences between the loser's and subject's opinions made subjects unwilling to help (return the lost packet) when information about the social environment suggested a negative state of affairs, e.g., quality of life deteriorating. However, when information about the social environment suggested a positive state of affairs, subjects were willing to help, even if there was little similarity of opinion. In the second study, subjects learned that the loser of the packet agreed with their views on one opinion but disagreed on another. In this study, one of the two opinions concerned the same social issue as the one described in the survey report. Results demonstrated that subjects helped when there was agreement on the social issue that was also highlighted in survey reports of a negative state of affairs in the social environment and withheld help when there was disagreement on this issue. There were trends for the same result with information about a positive state of affairs in the social world.     

Memory for actions: Self-performed tasks and the reenactment effect

Encoding action phrases by enactment (self-performed tasks, or SPTs) leads to better memory than does observing actions (experimenter-performed tasks, or EPTs) or hearing action phrases (Engelkamp, 1998). In addition, recognition memory for SPTs is enhanced when test items are reenacted. Experiment 1 demonstrated a reenactment effect for EPTs, as well as for SPTs, indicating that the effect can be based on visual, as well as motoric, feedback. However, the reenactment effect in SPTs was found even when the participants were blindfolded at test (Experiment 2), indicating that the basis for the reenactment effect differs across SPTs and EPTs. Experiments 3 and 4 provided additional evidence that visual feedback is not critical for reenactment recognition in the case of SPTs. In addition, these experiments failed to show a hand congruency effect (enhanced recognition when the same hand enacts at study and at test), indicating that this effect is not as generalizable as the reenactment effect. These results have important implications for the motor-encoding hypothesis of the enactment effect.     

The Effect of Mood and Social Outlook on Hypothetical Juridic Decisions1

Data are reported for a laboratory experiment which examines both the impact of information about remote social events on judgments of defendants' guilt or innocence in two court cases and the roles of cognitive and affective elements in mediating these judgments. Subjects were exposed to one of four pretested news bulletins which covaried cognitive factors (positive or negative social information) and affective ones (positive or negative mood stimuli). In accord with previous findings, the results indicate that social information and the changes in social outlook that it caused were of primary importance in altering subjects' judgments about defendants. Subjects who heard positive social information in radio newscasts were more lenient in their judgments of defendants than were those who heard negative social information. Additional findings pertaining to the mediators of this effect suggest that positive mood amplified the impact of social information whatever its direction, while negative mood attenuated it.     

Videotherapie bei postpartalen Störungen

Video recording is currently part of in- and out-patient therapy programs for parents with infants. The observation and analysis of video sequences allow the patient to gain an extraordinary insight with respect to its own experience and behaviour. Video Microanalytical Therapy (VMT) looks for the mother’s positive qualities in her relationship to the child and employs these qualities in order to support successful interactions. VMT is well-suited to the treatment of mothers with postpartal affective or psychotic disorders, because the typical cognitive distortions and reduced perception shown by these mothers can be avoided to a large extent through the use of pictures. In this study, a video microanalytical therapy concept will be presented, that was developed for the treatment of postpartally disordered mothers at the Psychiatric Centre Nordbaden in Wiesloch, Germany.     

Kasuistik zur Kindeswohlgefährdung bei postpartaler Depression

Postpartum psychiatric disorders adversely affect the relationship between the mother and her baby, frequently in a very serious way. It is common that both objective and subjective aspects of this relationship would be negatively influenced by the maternal pathology. The disturbances that arise from the psychiatric disorders could become a hostile and rejecting quality and could be unfavourable to the long-term development of the child. Obsessional impulses to harm the baby are not rare by mothers in the postpartum period. A large figure of severely depressed and psychotic mothers admited to have had some thoughts of harming or to killing the baby. Some of them have already done harmful things to their babies. Ideations of infanticide or child abuse are not always associated with psychiatric disorders (i.e. depressive symptoms or delusion). They could be a consequence of a severe Bonding disorder.