Aripiprazole-related tardive dyskinesia

The low prevalence of extrapyramidal symptoms associated with atypical antipsychotics has led to their widespread use during the past decade. Aripiprazole, the newest medication in this class, has been associated with extrapyramidal symptoms (eg, akathisia) and with improvement of tardive dyskinesia (TD), but to date it has not been associated with the development of TD. We report a case of TD associated with the use of aripiprazole 15 mg/day for 18 months for refractory depression. Symptoms of TD resolved within several weeks of discontinuation of aripiprazole.     

Age-related accelerated tapping response in healthy population

Different types of rapid tapping responses were described in the finger-tapping test. The "Hastening phenomenon" was described as an abnormal motor response in patients with Parkinson's disease. Accelerated tapping has been shown in a healthy elderly sample. It is not clear whether accelerated tapping relates to the hastening phenomenon or characterizes normal aging. We hypothesized that this sample of 21 healthy elderly people showed increased accelerated tapping but not hastening phenomenon. To assess this hypothesis, 20 healthy young and 21 elderly subjects performed a tapping test, requiring responses from 1 to 6 Hz. The healthy elderly sample showed increased accelerated tapping but not increased "hastening phenomenon." We conclude that Accelerated tapping may represent age-related motor processes unlike the hastening phenomenon characterizing Parkinson's disease.     

Against Perceptual Conceptualism

This paper is concerned with the question of whether mature human experience is thoroughly conceptual, or whether it involves non-conceptual elements or layers. It has two central goals. The first goal is methodological. It aims to establish that that question is, to a large extent, an empirical question. The question cannot be answered by appealing to purely a priori and transcendental considerations. The second goal is to argue, inter alia by relying on empirical findings, that the view known as ‘state-conceptualism’ is false. We will argue that our experiences do involve non-conceptual elements. That is, a subject may enjoy an experience with a particular phenomenal aspect, without possessing the concept needed for the specification of the content of that aspect, and moreover, without being able to acquire that concept upon having that experience.     

THE KNOWLEDGE ARGUMENT AND HIGHER-ORDER PROPERTIES

The paper argues that Jackson's knowledge argument fails to undermine physicalist ontology. First, it is argued that, as this argument stands, it begs the question. Second, it is suggested that, by supplementing the argument (and taking one of its premises for granted), this flaw can be remedied insofar as the argument is taken to be an argument against type‐physicalism; however, this flaw cannot be remedied insofar as the argument is taken to be an argument against token‐physicalism. The argument cannot be supplemented so as to show that experiences have properties which are illegitimate from a physicalist perspective.     

Interactions between anxious mothers and their infants: An integration of theory and research findings

Children of highly anxious mothers are at risk for developmental difficulties including anxiety disorders, and “anxious maternal behavior” and disturbed mother–infant interactions have been implicated in the transmission of risk. In this article, we describe interactions between mothers who are highly anxious and their young infant, based on the few directly relevant observation studies that are available. For more detail, we draw on a broader literature including studies of depressed mothers and developmental theory. Our goal is to describe how the interactions between anxious mothers and infants look to an outside observer and how they may feel to mothers and infants. We also discuss possible bases for their disturbed interactive behavior, the impact that the disturbances can have on both mothers and infants, buffers and risk factors, and routes to short‐term intervention. Finally, we suggest directions for future research on maternal anxiety and anxious maternal behavior and the significance of such research for clinicians and researchers.     

Motivational Cognitivism and the Argument from Direction of Fit

An important argument for the belief-desire thesis is based on the idea that an agent can be motivated to act only if her mental states include one which aims at changing the world, that is, one with a “world-to-mind”, or “telic”, direction of fit. Some cognitivists accept this claim, but argue that some beliefs, notably moral ones, have not only a “mind-to-world”, or “thetic”, direction of fit, but also a telic one. The paper first argues that this cognitivist reply is deficient, for only the “dominant” direction of fit of an attitude is responsible for its character and function. Further, it seems that the dominant direction of fit of an attitude is determined by its psychological mode, and so all beliefs seem to have a dominant thetic direction of fit, and to be motivationally inert. The main part of this paper, however, is devoted to explaining how it is that attitudes, like moral attitudes, can truly have two directions of fit in a way which enables them to be both cognitive and motivational. Reflection on the nature of beliefs suggests that the claim that the dominant direction of fit of an attitude is determined by its psychological mode should be qualified. The reasons beliefs provide draw their authority for the agent – their demanding nature – from the objects represented by these beliefs, and so, it is the beliefs’ content which determine their dominant direction of fit, as far as their role in practical reasoning is concerned. Thus, in the sense relevant to practical reasoning a belief with a normative content does have a dominant telic direction of fit. At the same time, in the sense relevant to its satisfaction conditions a moral belief has a dominant thetic direction of fit, which underlies its classification as a cognitive attitude. Cognitivists, then, can have it both ways.     

Against Strong Cognitivism: An Argument from the Particularity of Love

According to the view we may term “strong cognitivism”, all reasons for action are rooted in normative features that the motivated subject (explicitly or implicitly) takes objects to have independently of her attitudes towards these objects. The main concern of this paper is to argue against strong cognitivism, that is, to establish the view that conative attitudes do provide subjects with reasons for action. The central argument to this effect is a top‐down argument: it proceeds by an analysis of the complex phenomenon of love and derives a conclusion regarding the (motivational and normative) nature of more basic mental phenomena—particular desires. More specifically, its starting point is the crude intuition that the significance conferred by love upon its objects is of a distinctively personal kind—an intuition that is expressed by the apparent non‐substitutability of two similar subjects only one of whom is loved with respect to their importance for the lover. I argue that the initial notion of non‐substitutability can be refined and modified so as to form a real challenge to all versions of strong cognitivism and to establish the existence of attitude‐dependent reasons.     

National cultures, performance appraisal practices, and organizational absenteeism and turnover: a study across 21 countries

Performance appraisal (PA) is a key human resource activity in organizations. However, in this global economy, we know little about how societal cultures affect PA practices. In this study, we address this gap by focusing on 2 complementary issues: (a) the influence of societal (national) cultural practices on PA practices adopted by organizations and (b) the contribution of the level of congruence between societal cultural practices and the characteristics of organizational PA practices to absenteeism and turnover. The results, based on a large data set across multiple countries and over 2 time periods, support the hypothesized effects of societal (national) cultural practices on particular PA practices and the interactive effects of societal cultural practices and PA practices on absenteeism and turnover. We discuss theoretical and practical implications of our findings.