The modification of attentional bias to emotional information: A review of the techniques,mechanisms, and relevance to emotional disorders

A negative bias in the deployment of attention to emotional stimuli is commonly found in both anxiety and depression. Recent work has highlighted that such biases are causally related to emotional vulnerability, suggesting that interventions that ameliorate them may be therapeutic. Here, we review the evidence that attentional bias can be modified using both pharmacological and psychological interventions. We highlight the behavioral and neuroimaging studies that suggest that these interventions impact upon attention via alteration of distinct neural mechanisms. Specifically, pharmacological interventions appear to influence the initial deployment of attention via an effect on the amygdala-based stimulus appraisal system, whereas psychological interventions influence attention at later time points and may alter activity in the lateral prefrontal cortex. Finally, we suggest a conceptual framework that embraces both pharmacological and psychological approaches and consider the possible implications of this work for future research and treatment development.     

Leibniz on Infinite Numbers,Infinite Wholes,and Composite Substances

Leibniz claims that nature is actually infinite but rejects infinite number. Are his mathematical commitments out of step with his metaphysical ones? It is widely accepted that Leibniz has a viable response to this problem: there can be infinitely many created substances, but no infinite number of them. But there is a second problem that has not been satisfactorily resolved. It has been suggested that Leibniz's argument against the world soul relies on his rejection of infinite number, and, as such, Leibniz cannot assert that any body has a soul without also accepting infinite number, since any body has infinitely many parts. Previous attempts to address this concern have misunderstood the character of Leibniz's rejection of infinite number. I argue that Leibniz draws an important distinction between ‘wholes’ – collections of parts that can be thought of as a single thing – and ‘fictional wholes’ – collections of parts that cannot be thought of as a single thing, which allows us to make sense of his rejection of infinite number in a way that does not conflict either with his view that the world is actually infinite or that the bodies of substances have infinitely many parts.     

The effects of multiple-exemplar self-instructional training on high school students' generalized conversational interactions

A multiple-baseline-across-students design was used to investigate the effects of multiple-exemplar self-instructional training on the acquisition and generalization of conversational interaction of 4 high school students with mental retardation. The multiple-exemplar component of the model consisted of (a) several peers without disabilities teaching the use of a self-instructional social skills strategy across diverse examples of conversational interactions and across two settings and (b) assessing the generalized effects of training across additional peers and one setting. Findings indicated that peers were effective in teaching the multiple-exemplar strategy and that peer training was associated with systematic increases in generalized conversational interactions with familiar and unfamiliar peers with and without disabilities in an additional setting. Social validation data indicated that following multiple-exemplar training, all participants' performances approximated those of general education students and was judged by others to have improved.     

Test–retest reliability and task order effects of emotional cognitive tests in healthy subjects

Little is known of the retest reliability of emotional cognitive tasks or the impact of using different tasks employing similar emotional stimuli within a battery. We investigated this in healthy subjects. We found improved overall performance in an emotional attentional blink task (EABT) with repeat testing at one hour and one week compared to baseline, but the impact of an emotional stimulus on performance was unchanged. Similarly, performance on a facial expression recognition task (FERT) was better one week after a baseline test, though the relative effect of specific emotions was unaltered. There was no effect of repeat testing on an emotional word categorising, recall and recognition task. We found no difference in performance in the FERT and EABT irrespective of task order. We concluded that it is possible to use emotional cognitive tasks in longitudinal studies and combine tasks using emotional facial stimuli in a single battery.