Influence of brain-derived neurotrophic factor and catechol O-methyl transferase polymorphisms on effects of meditation on plasma catecholamines and stress

Meditation may show differential effects on stress and plasma catecholamines based on genetic polymorphisms in brain-derived neurotrophic factor (BDNF) and catechol O-methyl transferase (COMT). Eighty adults (40 men, 40 women; mean age 26 years) who practiced meditation regularly and 57 healthy control adults (35 men, 22 women; mean age 26 years) participated. Plasma catecholamines (norepinephrine (NE), epinephrine (E), and dopamine (DA)) concentrations were measured, and a modified form of the Stress Response Inventory was administered. The results were analyzed using two-way analysis of covariance (ANCOVA) with control and meditation subjects, gene polymorphism as factors, and meditation duration as the covariate. Two-way ANCOVA showed a significant interaction between control and meditation subjects, and BDNF Val66Met polymorphism on DA/NE+DA/E (p = 0.042) and NE/E+NE/DA (p = 0.046) ratios. A significant interaction was found for control and meditation subjects with COMT Val158Met polymorphism and plasma NE concentrations (p = 0.009). Post hoc ANCOVA in the meditation group, adjusted for meditation duration, showed significantly higher plasma NE concentrations for COMT Met carriers than COMT Val/Val subjects (p = 0.025). Significant differences of stress levels were found between the control and meditation subjects in BDNF Val/Met (p < 0.001) and BDNF Met/Met (p = 0.003), whereas stress levels in the BDNF Val/Val genotype did not differ between the control and meditation groups. This is the first evidence that meditation produces different effects on plasma catecholamines according to BDNF or COMT polymorphisms.     

Exploring the creation of learner-centered e-training environments among retail workers: a model development perspective

Current business leaders continue to adopt e-learning technology despite concerns regarding its value. Positing that the effectiveness of e-training depends on how its environment is managed, we argue that a learner-centric approach is necessary in order to achieve workplace training goals. We subsequently develop a theoretical model that is aimed at identifying the key components of learner-centered e-training environments, which serve the function of providing a benchmarked approach for evaluating e-training success. The model was empirically tested using data from an Internet survey of retail industry employees and partial least squares techniques were used for analysis. Based on the findings, this study clarifies what is needed for successful e-training in terms of instructional design, system design, and organizational support.     

Social exchange relationships and exchange ideologies of employees and supervisors: A three-way interaction toward employee creativity

This study aims to better understand the effects of social exchange relationships between employees and their organizations (perceived organizational support [POS]), and their leaders (leader–member exchange [LMX]) on their creativity. To this end, we investigated how exchange ideologies of employees and supervisors affect the relationship between POS/LMX and employee creativity using a three-way interaction test. Building on the social exchange theory, the results from our sample of 254 leader–employee dyads indicated that the relationship between POS/LMX and employee creativity is significantly more positive for an employee with strong exchange ideology than for an employee with weak exchange ideology. Moreover, POS and LMX had the strongest positive relationships with creativity when both employees and supervisors had higher levels of exchange ideology. The implications of our results and future research directions are discussed.     

Together towards Life in the Korean Context: Missiological Implications for the Korean Church

This paper examines the implications of Together towards Life: Mission and Evangelism in Changing Landscapes (TTL) in the Korean context. TTL presents a renewed understanding of mission and challenges the mission activity of the Korean church and mission community. The paper explores some missiological implications of TTL for the once marginalized Korean church, which has become the centre of global Christianity. The world church has begun to recognize the rise of the non‐Western churches and the emerging roles of the Korean church. TTL, with a study guide, and Ecumenical Missiology should serve as helpful resources for teaching and training theology students and field missionaries. 1     

Predicting Individuals’ Experienced Fear From Multimodal Physiological Responses to a Fear-Inducing Stimulus

Emotions are experienced differently by individuals, and thus, it is important to account for individuals’ experienced emotions to understand their physiological responses to emotional stimuli. The present study investigated the physiological responses to a fear-inducing stimulus and examined whether these responses can predict experienced fear. A total of 230 participants were presented with neutral and fear-inducing film clips, after which they self-rated their experienced emotions. Physiological measures (skin conductance level and response: SCL, SCR, heart rate: HR, pulse transit time: PTT, fingertip temperature: FT, and respiratory rate: RR) were recorded during the stimuli presentation. We examined the correlations between the physiological measures and the participants’ experienced emotional intensity, and performed a multiple linear regression to predict fear intensity based on the physiological responses. Of the participants, 92.5% experienced the fear emotion, and the average intensity was 5.95 on a 7-point Likert scale. Compared to the neutral condition, the SCL, SCR, HR, and RR increased significantly during the fear-inducing stimulus presentation whereas FT and PTT decreased significantly. Fear intensity correlated positively with SCR and HR and negatively with SCL, FT, PTT, and RR. The multiple linear regression demonstrated that fear intensity was predicted by a combination of SCL, SCR, HR, FT, and RR. Our findings indicate that the physiological responses to experiencing fear are associated with cholinergic, sympathetic, and α-adrenergic vascular activation as well as myocardial β-sympathetic excitation, and support the use of multimodal physiological signals for quantifying emotions.