Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Effects of Acute Stress or Centrally Injected Interleukin-1beta on Neuropeptide Expression in the Immune System

Acute stress stimulates the expression and release of corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, and the pro-opiomelanocortin products beta-endorphin and ACTH from the anterior pituitary. These neuropeptides are also expressed in immune tissues, and it has been proposed that they may modulate immune responses to stress through paracrine mechanisms. We subjected rats to restraint stress or central injection of interleukin (IL)-1beta to determine whether these acute stimuli can alter the expression of neuropeptides in the spleen and thymus. Restraint stress significantly increased the contents of all these neuropeptides in thymic, but not splenic, extracts. A single icv injection of IL-1beta increased contents of CRH, AVP, ACTH and beta-endorphin in the spleens of both sham-operated and adrenalectomised (ADX) rats. IL-1beta increased thymic contents of CRH and ACTH in sham-operated rats but these increases were not observed in ADX rats. These results suggest that the effects of IL-1beta on neuropeptide expression in the spleen are independent of glucocorticoids, whereas IL-1beta stimulation of neuropeptide expression in the thymus is dependent on circulating glucocorticoids. There were significant correlations between increases in CRH, ACTH and beta-endorphin in the spleen, and between CRH and ACTH in the thymus, consistent with the suggestion that IL-1beta-induced increases in ACTH and beta-endorphin may be mediated through CRH. These results provide evidence that stressors can directly influence neuropeptide expression in immune tissues. Thus stress may influence immune functions through paracrine mechanisms involving locally synthesised neuropeptides as well as through activation of the hypothalamo-pituitary-adrenal axis.     

Shyness and Psychosocial Functioning in South Korean Children

The purpose of this study was to examine whether anxious shyness and regulated shyness, initially identified in the Chinese culture, is found in South Korean children, and to explore whether these two forms of shyness were differentially related to children's psychosocial functioning. Participants were 544 fourth to sixth grade children (251 girls, M age = 11.38 years old) who were recruited from an elementary school in Bucheon City, South Korea. Children's anxious and regulated shyness were measured using peers' nominations and teachers' ratings, whereas their social preference and social impact were assessed using peers' nominations. Parents rated their children's temperamental shyness and effortful control, and children self‐reported their loneliness and interpersonal concerns. The results of confirmatory factor analysis replicated the two factor model of shyness found in previous studies of Chinese children. Anxious shyness and regulated shyness were positively associated and were similarly related to temperamental shyness. Anxious shyness was negatively related to effortful control and social preference, and positively associated with self‐reported loneliness and interpersonal concerns, whereas regulated shyness was positively related to effortful control and social preference and negatively associated with loneliness and social impact. These results were generally consistent with prior Chinese findings and provided preliminary support for the construct validity of anxious and regulated shyness in another Asian culture that emphasizes interdependence and modesty. Copyright © 2013 John Wiley & Sons, Ltd.     

A Cyberbullying Intervention for Hong Kong Chinese College Students

A cyberbullying intervention was developed and empirically tested with 137 Hong Kong Chinese College students. The intervention was designed to change students’ attitudes about cyberbullying behavior and increase their awareness of cyberbullying. Participants were assigned to an experimental or control group. They completed questionnaires before the intervention (Time 1; T1), immediately after the intervention (Time 2; T2), and again eight weeks later (Time 3; T3). The experimental group participated in a 1-h intervention where they were presented with a simulated Facebook page showing the helpless feelings of cyber-victims, watched video clips of the consequences of cyberbullying, and engaged in small group discussions and a self-reflection writing task. Results showed that participants who received the intervention experienced an increase in their awareness and had more negative attitudes toward cyberbullying (i.e., the perception that cyberbullying is unacceptable behavior) than did the control group. In addition, those who reported being highly engaged in the intervention maintained the positive effects at the 8-week follow-up. The results demonstrate the feasibility and effectiveness of a short-term cyberbullying intervention for college students and that level of participant engagement contributes to its effectiveness.     

大学二年级学生人际宽恕与报复心理及其与抑郁的关系研究

采用沉思量表、报复动机量表、宽恕倾向量表、宽恕态度量表和流调中心用抑郁量表对236名大二学生进行问卷调查,综合探讨大学生人际宽恕和报复心理及其与抑郁的关系。研究发现:(1)男大学生的报复倾向显著高于女大学生。(2)宽恕倾向与报复倾向及对侵犯的沉思程度显著负相关。沉思程度和抑郁显著正相关。(3)沉思程度和宽恕倾向对抑郁分别具有显著的正向和负向的预测作用。(4)大学生的宽恕倾向和宽恕态度的相互作用以及宽恕倾向和报复倾向之间的交互作用对抑郁均没有显著预测作用。     

Toddlers' responses to the distress of their peers

Toddlers' spontaneous prosocial responses to their peer's crying distress were examined in this study. Forty-three children ranging in age from 16 to 33 months were observed as they interacted with their peers in day-care centers. Each child was observed for 16, 5-min periods. If a child cried, the response of the peer and the response of the teacher were recorded. Teachers independently identified peer friendships. Ninety-three percent of peer responses to cries were prosocial in nature. Children who responded more often prosocially to crying peers were the children who more often cried themselves. The response of the teacher to the child's own cry was related to that child's response to a peer. Children were more likely to respond to friends' cries than to cries of acquaintances.     

Victimization in South Korean children's peer groups

This study reports a cross-sectional investigation of the behavioral, academic, and psychosocial correlates of victimization in South Korean children's peer groups. The participants were 122 children (66 boys, 56 girls; from 10–12-years-old) recruited from a primary school in Seoul, South Korea. Multi-informant assessments (peer nominations, teacher ratings, and self-reports) of peer victimization, social behavior, loneliness/social dissatisfaction, and academic functioning were obtained. Multivariate analyses indicated that peer victimization was associated with poor academic adjustment, loneliness, submissive–withdrawn behavior, aggression, and low levels of assertive–prosocial behavior. These findings suggest that there is considerable similarity in the social processes underlying peer group victimization across South Korean and Western cultural settings.     

Information processing bias against emotional facial expressions in social anxiety

The present study examined whether information processing bias against emotional facial expressions is present among individuals with social anxiety. College students with high (high social anxiety group; n  = 26) and low social anxiety (low social anxiety group; n  = 26) performed three different types of working memory tasks: (a) ordering positive and negative facial expressions according to the intensity of emotion; (b) ordering pictures of faces according to age; and (c) ordering geometric shapes according to size. The high social anxiety group performed significantly more poorly than the low social anxiety group on the facial expression task, but not on the other two tasks with the nonemotional stimuli. These results suggest that high social anxiety interferes with processing of emotionally charged facial expressions.     

Toward an Integration of Interpersonal Risk Models of Depression and Cognitive‐Behaviour Therapy

Empirical research has increasingly focused on interpersonal variables associated with the development and maintenance of depression. This article outlines some key interpersonal risk factors for depression, including anxious attachment, sociotropy, excessive reassurance seeking, interpersonal stress generation, reduced social support, social skills deficits, and social avoidance. Recommendations are made for how cognitive‐behavioural therapy may be adapted to address such factors. Specifically, suggestions are offered for how cognitive and behavioural interventions, such as cognitive restructuring, behavioural activation, behavioural experiments, and skills training, may be used with depressed clients to promote positive relationships and reduce maladaptive interpersonal behaviours.