The Gettier Intuition from South America to Asia

Journal of Indian Council of Philosophical Research - This article examines whether people share the Gettier intuition (viz. that someone who has a true justified belief that p may nonetheless fail...     

L-Type Voltage-Dependent Calcium Channel Blocker Nifedipine Enhances Memory Retention When Infused into the Hippocampus

Wistar rats with cannulae bilaterally implanted in the CA1 region of the dorsal hippocampus were trained in a step-down inhibitory avoidance task. Through these cannulae they received an infusion of 28 or 280 ng per side of the L-type voltage-dependent calcium channel antagonist nifedipine, or of its vehicle (20% dimethyl sulfoxide in saline). The two doses of the drug were studied by administration 0 or 30 min after training; in addition, the higher dose was studied by infusion 10 min before training. A retention test was carried out 24 h after the training session. The highest dose of nifedipine administered 0 min post-training enhanced test session performance of the animals compared to the control group; the effect of the lower dose was not statistically significant. There was no effect of the drug given 30 min post-training or 10 min pretraining. Despite the inability to discriminate direct neural from indirect vascular effects, these results are consistent with previous reports on nootropic actions of the dihydropyridine class of calcium channel blockers. The data are at variance with the amnestic effect of intrahippocampal nifedipine described by Lee and Lin (1991,Life Sciences,48,1333–1340), which may be attibuted to the different range of doses studied here. This might resemble the inverted U-shaped dose–response curve observed with another dihydropyridine, nimodipine, by other authors.     

An experiment in social engineering in serving the families of predelinquents

One hundred and two predelinquent adolescents were randomly assigned to one of two conditions: an experimental condition in which behavioral contracting services were offered both at home and in school or a control condition in which clients were told that they could not be accommodated by project therapists and were informed about the possibility of their receiving treatment in other programs in the community. Most of those who were assigned to the control condition did not avail themselves of services in these other programs. Results indicate that, relative to the controls, the behaviorally treated youth scored small but statistically significant improvement relative to the controls on five measures: ratings of school behavior by the person who originally referred them for service, by their teachers, by their mothers, and by their fathers, and ratings of their parent—child interactions as measured by their mothers. Gains were also reported in mothers' ratings of their children's behavior at home. The failure of significant gains to be made in two measures of school performance grades and attendance is explained by the failure o f the treatment techniques to over-come an age-related deterioration in these areas found among most children in the participating schools. The failure of fathers to find significant improvement in their relationships with the referred adolescents is viewed as a consequence of unanticipated changes in the intrafamilial balance of power resulting from contracting services. Finally, a subsidiary analysis showed that the contracting service appeared to offer the greatest gain to the demographically defined sub-groups of youths who are among the population-at-risk in many juvenile courts.This study was supported by Grant R01-MH21452 from the Center for Studies of Crime and Delinquency, National Institute of Mental Health. The authors wish to thank L. Nilles, who served as general administrator of this project, and C. Faller, S. Iman, P. Ippel, L. Lott, J. Marsh, C. Stephenson, J. Tanter, D. Virtue, and R. Welter, who served as therapists.     

Preserved orthographic length and transitional probabilities in written spelling in a case of acquired dysgraphia

We present the performance of a patient with acquired dysgraphia, DS, who has intact oral spelling (100% correct) but severely impaired written spelling (7% correct). Her errors consisted entirely of well-formed letter substitutions. This striking dissociation is further characterized by consistent preservation of orthographic, as opposed to phonological, length in her written output. This pattern of performance indicates that DS has intact graphemic representations, and that her errors are due to a deficit in letter shape assignment. We further interpret the occurrence of a small percentage of lexical errors in her written responses and a significant effect of letter frequencies and transitional probabilities on the pattern of letter substitutions as the result of a repair mechanism that locally constrains DS' written output.     

Visuospatial working memory for locations,colours, and binding in typically developing children and in children with dyslexia and non‐verbal learning disability

This study examined forward and backward recall of locations and colours and the binding of locations and colours, comparing typically developing children – aged between 8 and 10 years – with two different groups of children of the same age with learning disabilities (dyslexia in one group, non‐verbal learning disability [NLD] in the other). Results showed that groups with learning disabilities had different visuospatial working memory problems and that children with NLD had particular difficulties in the backward recall of locations. The differences between the groups disappeared, however, when locations and colours were bound together. It was concluded that specific processes may be involved in children in the binding and backward recall of different types of information, as they are not simply the resultant of combining the single processes needed to recall single features.