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Wistar rats of three age groups were tested in an automated tunnel-maze system of variable geometry to investigate whether changes in spontaneous locomotor activity and in learning and memory develop differentially or in a correlated fashion as a function of age. Senescent (30 months) as well as mature-adult (17 months) rats showed an age-correlated decline of locomotor activity as compared to the mature-young (5 months) group. Both working-memory (measured as within-trial arm discrimination performance) and reference-memory (measured as avoidance of "blind alley" visits) were severely affected in the senescent group, whereas the middle-aged animals suffered only from a working-memory deficit. The findings provide evidence that locomotor deficits do not necessarily interfere in the assessment of age-related changes in cognitive performance. Furthermore the results support the hypothesis that working and reference memory have different underlying physiological correlates and that these neuronal systems are differentially affected by the aging process. 相似文献
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S W?sser W Handrick F B Spencker W Braun 《Psychiatrie, Neurologie, und medizinische Psychologie》1988,40(2):95-101
Observations on three children with neurolisteriosis (one case of meningitis, two cases of meningoencephalitis, each Serovar 4 b), show that even after the neonatal period, listeriosis must not be ignored in the process of diagnosis and therapy. It is the bacteriological examination of the cerebrospinal fluid, together with the blood culture, and not clinical symptoms and serology that guarantee a timely diagnosis and therapy (ampicillin and gentamicin). 相似文献
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It is proposed that expert knowledge can operate as a cognitive cueing structure for the acquisition and retention of new information in memory. Two experiments are reported which demonstrate that expert knowledge about football and clothing can act as mnemonic cues for the recall of information newly associated with that knowledge. In Experiment 1 expert terms from the domains of football and clothing and those neutral nouns paired with them were both better recalled by experts than by non-experts. In Experiment 2 passages containing information contrary to factual knowledge about football and clothing were recalled better by experts than by non-experts, in spite of the fact that information in the passages contradicted what the experts already knew. The results of the two experiments were interpreted as showing that expert knowledge provides mental cues that have desirable mnemonic properties such as constructibility, associability, discriminability and invertibility. Also, the interpretation of expert knowledge as a cognitive cueing structure is compared to Ausubel's ideas regarding advance organizers. 相似文献
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David C. Rowe Laurie Chassin Clark C. Presson Debra Edwards Steven J. Sherman 《Journal of applied social psychology》1992,22(4):261-285
The prevalence of regular smoking increases rapidly during adolescence. We applied modeling methods from the study of epidemic infectious disease to smoking behavior. Our "epidemic" models dealt with the process of transition among four states: nonsmoker (susceptible), trier (exposed), regular smoker (infected), and ex-smoker (recovered). The best fitting model was one in which the transition from nonsmoker to trier was a social contagion process where nonsmokers contacted either triers or regular smokers. All other transitions were treated as constant rate processes in which a constant proportion of eligible individuals made the transition in a given year. The recursive equation model embodying these assumptions was able to predict accurately the proportion of adolescents in each state in Grades 6–11. Our results support a "stage" model of smoking, suggesting that different psychological and physiological processes are involved in the initiation of smoking than in developing a habit of regular smoking. A possible sex difference was found in the non-contact transition between trier and smoker states, with the transition being more probable in females than in males. 相似文献
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The authors examined characteristics of Finnish mothers (N = 924) who use hostile child-rearing practices (i.e., they ignore the child, are punitive and irritable, and perceive the child as a burden), practices that have been shown (R?ikk?nen & Keltikangas-J?rvinen, 1992) to predispose children to Type A behavior. The results of this study indicate that two factors--Type A behavior in the mothers and the mothers' sociodemographic background (low occupational status, low educational level and young age)--increase the probability of the mothers' treating their children in a hostile manner. Also, the mothers of boys in this study reported more hostile child-rearing practices than the mothers of girls did. 相似文献