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In endless facets of physiology, there are points of homeostatic balance, such that too much or too litttle of something can both be deleterious (i.e., an "inverse U" pattern). This is particularly true when considering glucocorticoids (GCs), the adrenals steroid secreted during stress. In the first part of this paper, I review a number of realms in which a paucity and an excess of GCs are both damaging. Some findings are classical (for example, concerning GC effects upon body weight), while some are quite recent and have considerable implications for both physiology and pathophysiology (for example, inverse U's of GC actions in the realm of immunity and neuronal survival). The second part of the review considers the far thornier issue of how such inverse U's of GC actions are generated on a cellular and molecular level. One solution that has evolved, primarily in the hippocampus within the nervous system, involves the presence of two different types of receptors for GCs within the same cells; so long as the two receptors have very different affinities and mediate opposing effects on some cellular endpoint, an inverse U will emerge. The second solution, found in a number of peripheral tissues, involves GCs having opposing effects on the amount of some signal being generated (e.g., an immune cytokine) and the sensitivity of target tissues to that signal; under conditions that appear to be physiologically relevant, inverse U's emerge from this pattern as well. The final section of this review considers the enormous role played by Bruce McEwen in the emergence of this literature. I suggest that while much of this obviously has to do with the facts that have come from his group, another substantial contribution is from his steadying and supportive personality, the veritable embodiment of homeostatic balance.  相似文献   
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This study investigated developmental and sex-related differences in affective decision making, using a two-deck version of Children's Gambling Task administered to 3- and 4-year-old children. The main findings were that 4-year-old children displayed better decision-making performance than 3-year-olds. This effect was independent of developmental changes in inductive reasoning, language, and working memory. There were also sex differences in decision-making performance, which were apparent only in 3-year-old children and favored girls. Moreover, age predicted awareness of task and the correlation between the latter and decision-making performance was significant, but only in 4-year-old children. This study thus indicates that there is a remarkable developmental leap in affective decision making, whose effects are apparent around the age of 4, which according to our results, also marks the age when the correlation of declarative knowledge and decision-making performance becomes significant.  相似文献   
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Mihal, W., Sorce, P., & Comte, T. (1984). A process model of individual career decision making. Academy of Management Review, 9, 95–103. Stumpf, S., & Hartman, K. (1984). Individual exploration to organizational commitment or withdrawal. Academy of Management Journal, 27, 308–329.  相似文献   
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Gelso, C., Prince, J., Cornfeld, J., Payne, A., Royalty, G., & Wiley, M. (1985). Quality of counselors intake evaluations for clients with problems that are primarily vocational versus personal. Journal of Counseling Psychology, 32, 339–347. Pinkney, J., & Jacobs, D. (1985). New counselor's and personal interest in the tasks of career counseling. Journal of Counseling Psychology, 32, 454–457.  相似文献   
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Social influence theory suggests that counseling is an interpersonal influence process. This article reviews the literature on the model and suggests future directions for research.  相似文献   
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