Effectiveness of time-out: a comparison of psychiatric, correctional and day-treatment programs

The effectiveness of a time-out intervention for adolescent psychiatric patients, adjudicated (delinquent) youth, and behaviorally disordered youngsters was explored in this study. The research was conducted in three psychiatric hospitals for children and adolescents, a facility for adjudicated youth, and in a day-treatment program. Utilizing a comparative outcome model, 813 occurrences of time-out with 274 youth were investigated in order to assess levels of effectiveness. The results indicated that time-out had a significant impact, and the use of a child-care specialist as time-out monitor improves overall effectiveness. Important implications for practicing professionals and clinical researchers are noted.     

SYMLOG: Clinical technology for therapist family of origin and family system appraisal

SYMLOG, an acronym for Systematic Multiple Level Observation of Groups, reflects a technology for the quantification and graphic organization of subjective observational data. The SYMLOG field diagram-a graphic diagram which reflects relational interactions on three dimensions-provides the opportunity to analyze the admixture of therapist family of origin dynamics in conjunction with family relational behaviors. This article presents a sample SYMLOG clinician family of origin evaluation with accompanying elaboration surrounding SYMLOG field theory.     

Child sexual abuse: offenders,disclosure, and school-based initiatives

Children are being sexually abused at an alarming rate. Prevalence estimates suggest that one out of four girls and one out of ten boys experience sexual abuse. This paper examines the devastating impact of child sexual abuse and explores the contributions of school-based interventions to remedy the problem.     

An analysis of moral issues affecting patenting inventions in the life sciences: A European perspective

Following the 1980 US Supreme Court decision to allow a patent on a living organism, debate has continued on the moral issues involved in biotechnology patents of many kinds and remains a contentious issue for those opposed to the use of biotechnology in industry and agriculture. Attitudes to patenting in the life sciences, including those of the research scientists themselves, are analysed. The relevance of morality to patent law is discussed here in an international context with particular reference to the law of the European Patent Convention administered by the European Patent Office (EPO). The EPO has been the principal forum for opposition to such patents and the few cases under dispute in the EPO are reviewed, including patents for the onco-mouse, human relaxin gene, and the PGS herbicidally resistant plant (gmo). Morality provisions in the European Parliament and Council Directive 98/44/EC are also summarised.     

Psychosis and autism as diametrical disorders of the social brain

Autistic-spectrum conditions and psychotic-spectrum conditions (mainly schizophrenia, bipolar disorder, and major depression) represent two major suites of disorders of human cognition, affect, and behavior that involve altered development and function of the social brain. We describe evidence that a large set of phenotypic traits exhibit diametrically opposite phenotypes in autistic-spectrum versus psychotic-spectrum conditions, with a focus on schizophrenia. This suite of traits is inter-correlated, in that autism involves a general pattern of constrained overgrowth, whereas schizophrenia involves undergrowth. These disorders also exhibit diametric patterns for traits related to social brain development, including aspects of gaze, agency, social cognition, local versus global processing, language, and behavior. Social cognition is thus underdeveloped in autistic-spectrum conditions and hyper-developed on the psychotic spectrum.;>We propose and evaluate a novel hypothesis that may help to explain these diametric phenotypes: that the development of these two sets of conditions is mediated in part by alterations of genomic imprinting. Evidence regarding the genetic, physiological, neurological, and psychological underpinnings of psychotic-spectrum conditions supports the hypothesis that the etiologies of these conditions involve biases towards increased relative effects from imprinted genes with maternal expression, which engender a general pattern of undergrowth. By contrast, autistic-spectrum conditions appear to involve increased relative bias towards effects of paternally expressed genes, which mediate overgrowth. This hypothesis provides a simple yet comprehensive theory, grounded in evolutionary biology and genetics, for understanding the causes and phenotypes of autistic-spectrum and psychotic-spectrum conditions.     

Schizotypy,cognitive performance,and genetic risk for schizophrenia in a non-clinical population

Schizophrenia risk alleles are expected to mediate effects on cognitive task performance, and aspects of personality including schizotypy, in nonclinical populations. We investigated how 32 of the best-validated schizophrenia risk alleles, singly and as summed genetic risk, were related to measures of schizotypal personality and measures of two aspects of cognitive performance, verbal skills (vocabulary) and visual-spatial skills (mental rotation), in healthy individuals. Summed genetic risk score was not associated with levels of total schizotypy or its three main subscales. Similarly, genotypic variation at none of the individual risk loci was related to cognitive performance measures, after correction for multiple tests. Higher overall genetic risk score was, however, associated with lower performance on the mental rotation test in males, with a broad set of loci contributing to this effect. These results imply that there is a lack of linear, genetically-based continuity connecting schizotypal cognition with the expression of schizophrenia itself, and indicate that, for males, higher genetic risk of schizophrenia exerts negative effects on visual-spatial skills, as measured by mental rotation.     

Restraint and seclusion with institutionalized adolescents

Tens of thousands of the nation's young people are placed in psychiatric and criminal justice programs annually. Within those settings, many confront an assortment of restraint and seclusionary measures. This paper discusses the population of young people exposed to such procedures and examines the implications within these settings and elsewhere.