Randomized controlled trial of an intervention to prevent adherence failure among HIV-infected patients initiating antiretroviral therapy.

OBJECTIVE: Compare the efficacy of a multicomponent social support intervention to standard-of-care counseling on medication adherence among HIV-infected patients initiating antiretroviral therapy. DESIGN: Randomized controlled trial. Generalized estimating equations tested for differences in the percentage of participants achieving 90% adherence. MAIN OUTCOME MEASURES: Pill-taking, electronically monitored over 6 consecutive months; plasma viral load (VL), assessed at 3 and 6 months following initiation of therapy. RESULTS: Of 226 participants who were randomized and began the trial, 87 (38%) were lost to the study by 6 months. The proportion of adherent participants declined steadily over time, with no time by group interaction. Sustained adherence was associated with increased odds of achieving an undetectable VL (OR=1.78; 95% CI=1.01, 3.13). In intention-to-treat analyses, a larger proportion of the intervention group than the control group was adherent (40.15% vs. 27.59%, p=.02) and achieved an undetectable VL p=.04). However, the majority of participants who remained on study experienced some reduction in VL (>or=1-log drop or undetectable), regardless of experimental condition. CONCLUSION: The multicomponent social support intervention significantly improved medication adherence over standard-of-care counseling; evidence for improved virologic outcomes was inconsistent. Early discontinuation of care and treatment may be a greater threat to the health of HIV patients than imperfect medication-taking.     

An inexpensive real-time microcomputer-based cognitive laboratory system

A computer system, based on the Radio Shack Color Computer, for running experiments in cognitive psychology is described. The system was designed according to the following principles: first, all of the equipment should consist of inexpensive, off-the-shelf components; second, the language used to implement experiments should have real-time commands embedded within the character strings to be displayed, and these real-time commands should be interpreted at run time; third, the system should serve multiple subjects, yet one host should be able to run display terminals for several subjects on independent experiments; and fourth, the system should be able to interface to other display devices and other response-recording devices. Two examples of other devices are discussed: an oscilloscope for rapid visual display and an Apple Macintosh for display of pictures.     

A model of visual spatio-temporal memory: The icon revisited

With a minimal set of assumptions resulting from considerations about the perception of temporal structure, we argue for the existence of a spatio-temporal memory established by the mapping of time into simultaneous physical properties. The important point of this model is the distinction between external, physical time and the internal representation of time. An immediate consequence of such a structure is the emergence of properties usually associated with the concept of iconic memory or informational persistence. Some of these properties may hence be regarded as epiphenomena produced by the testing of a spatio-temporal system with tachistoscopic spatial stimuli. The model can explain properties of the immediate memory span, the lack of effect of exposure duration on tachistoscopic report, the partial-report superiority, the decay of iconic memory, and effects of a backward mask. It does not only avoid the incompatibility problems of the frozen-image concept in dynamic vision, but also provides an adequate basis for the processing of time-varying scenes.     

Mental imagery and dyslexia: a deficit in processing multipart visual objects?

Dyslexic and normal control subjects memorized simple line patterns inside a grid and subsequently judged whether an "X" would have fallen on the pattern had it been present in an empty grid. The patterns were letters and novel shapes. The grids were presented to the left visual field, to the right visual field, or in central vision. Dyslexic subjects had difficulty generating images of multipart patterns, but this deficit was limited to letters. The findings suggest that dyslexics may have selective difficulty integrating visual information stored in long-term memory.     

COVID-19, Sex,Addictions, Women's Health,Care of the Elderly,and Medical Education

Journal of Religion and Health -     

Preference for Human (vs. Robotic) Labor is Stronger in Symbolic Consumption Contexts

Advances in robotics, automation, and artificial intelligence increasingly enable firms to replace human labor with technology, thereby fundamentally transforming how goods and services are produced. From both managerial and societal points of view, it is therefore important to understand demand‐side incentives for firms to employ human labor. We begin to address this question by examining for which products and services consumers are more likely to favor human (vs. robotic) labor. In six studies, we demonstrate that consumers prefer human (vs. robotic) labor more for products with higher (vs. lower) symbolic value (e.g., when expressing something about one's beliefs and personality is of greater importance). We theorize that this is because consumers have stronger uniqueness motives in more (vs. less) symbolic consumption contexts (and associate human labor more strongly with product uniqueness). In line with this account, we demonstrate that individual differences in need for uniqueness moderate the interaction between production mode and symbolic motives and that a measure of uniqueness motives mediates the effect of consumption context on preferences for human (vs. robotic) production.     

Subgroup differences in situational judgment test scores: Evidence from large applicant samples

To promote diversity in organizations it is important to have accurate knowledge about subgroup differences associated with selection procedures. However, current estimates of subgroup differences in situational judgment tests (SJTs) are overwhelmingly based on range‐restricted incumbent samples that are downwardly biased. This study provides much‐needed applicant level estimates of SJT subgroup differences (N = 37,530). As a key finding, Black‐White differences (d = 0.66) were higher than in incumbent samples (d = 0.38). Overall, sex differences were small. Females scored higher for management jobs (d = ?0.13) and males scored higher for administrative jobs (d = 0.15). By analyzing applicant samples that do not suffer from range restriction, this study adds knowledge about subgroup differences in SJTs.     

Towards Transparency by Design for Artificial Intelligence

Science and Engineering Ethics - In this article, we develop the concept of Transparency by Design that serves as practical guidance in helping promote the beneficial functions of transparency...     

Children's reasoning about the causal significance of the temporal order of events

Four experiments examined children's ability to reason about the causal significance of the order in which 2 events occurred (the pressing of buttons on a mechanically operated box). In Study 1, 4-year-olds were unable to make the relevant inferences, whereas 5-year-olds were successful on one version of the task. In Study 2, 3-year-olds were successful on a simplified version of the task in which they were able to observe the events although not their consequences. Study 3 found that older children had difficulties with the original task even when provided with cues to attend to order information. However, 5-year-olds performed successfully in Study 4, in which the causally relevant event was made more salient.     

A review of research on chaplains and community-based clergy in the Journal of the American Medical Association, Lancet, and the New England Journal of Medicine: 1998-2000

Based on the content analysis of quantitative research appearing in three medical journals, the authors conclude that, despite the shared ideal of providing spiritual care to patients on the part of physicians and chaplains, there is little attention given in these journals demonstrating and promoting this shared perspective. Suggestions for future research that would focus on this common medicine/religion interface and concern are noted.