Pharmacological effects on lateralized behavior

Sixteen student volunteers were administered a placebo and 50 mg. of chlorpromazine in tablet form, on separate occasions, two hours before testing. The three tests measured dichotic listening performance, lateral eye movements while answering questions about spatial location and verbal meaning, and lateralized facial expression while relating pleasant and unpleasant life incidents. Results showed that chlorpromazine increased the number of trials showing an ear advantage in dichotic listening. Chlorpromazine reduced lateral and increased vertical eye movements in response to the questions about spatial location and verbal meaning. Under the placebo both negative and positive emotions were expressed more in the left face. Although chlorpromazine did not affect this lateralization of negative emotions, the expression of positive emotions occurred equally often on the two sides of the face under chlorpromazine. Results may be related to an effect of chlorpromazine on the asymmetrical dopamine pathways of the brain. It is suggested that the findings may be related to a left hemisphere deficit in schizophrenia.     

Reader and text variables as determinants of discourse memory in adulthood

Young students, old students, and old nonstudents read and recalled short texts that were in either narrative or expository form. In addition, a set of six verbal ability measures thought to be related to discourse memory was obtained for all of the participants. Older subjects recalled less from the texts than younger subjects, and neither type of text nor student status modified the magnitude of the age differences. The set of verbal ability measures was adequately described by two principal components, one consisting of simple, speed-related skills, and the other consisting of more complex skills. Each set of variables predicted a proportion of discourse memory variance, and accounted for some of the variance that would otherwise be attributed to age. The results suggest that age differences in some basic cognitive skills related to reading effectiveness might underlie age differences in memory for discourse.     

Book reviews

Current Psychology -     

Common response processing and psychological refractoriness

This experiment examined whether structural considerations, that is the functional closeness of limb control centres (Kinsbourne and Hicks 1978), have a role to play in common processing models of psychological refractoriness. A typical double stimulation paradigm was used (Kantowitz 1974). On experimental trials, subjects responded with the right hand (RT1) to an auditory signal (0.80 probability). After a varied interstimulus interval (ISI) of 100, 200, 300 or 700 msec, one of three lights corresponding to one of the other limbs provided the signal for the second response (RT2). Control trials for RT1 and RT2 involved both stimuli, but subjects were required to make only one response. Results indicated that experimental RT1 was lengthened considerably over control values. While typical double stimulation effects were found at short ISIs, that is RT2 was lengthened, RT2 at long ISIs was actually faster than double stimulation control values. Although the RT results were not in a pattern that would be predicted by functional distance (Kinsbourne and Hicks 1978), within subject correlations of RT1 and RT2 by limb condition suggest that structural considerations may have a role to play. While within subject correlations were positive at all levels of ISI, they decreased as the interval between the two signals increased. The implications of these results for common processing models are discussed.     

Structural equation models of relationships between exercise and cognitive abilities

Data were obtained from 300 men and women aged 55 to 91. Separate structural equation models of relationships between physical exercise and 3 cognitive performance variables--reaction time, working memory, and reasoning--fit the data well. Other variables in the models were age, health, education, and morale. Age and exercise affected each performance variable directly; education had a direct effect on reasoning only. There were also indirect effects of age and health on performance variables, mediated through exercise. The main hypothesis of the study, that exercise contributes to performance, was supported. A large decrease in model fit resulted when the path from exercise to each performance variable was deleted. Hypotheses that age-related deficits are primarily accounted for by lack of exercise or by poor health were not supported.     

An object-oriented simulation of a brain system underlying human aggression

Neural structures involved in aggression were incorporated into a model on the basis of neuro-anatomical data. A software program written in Smalltalk, the Brain Structure Simulator (Seguin, 1994) was used to simulate the effects of activity levels of different brain structures. Relationships among brain structures were then tested by changing activity levels of key structures. Results were consistent with research reports on the brain basis of aggression (Albert, Walsh, & Jonik, 1993; Pontius, 1984).