Immune responses to lipopolysaccharide challenge in a tropical rodent (Funambulus pennanti): photoperiod entrainment and sex differences

Annual variation in day length (photoperiod) triggers changes in the immune system of seasonal breeders. The rationale behind this study was to delineate any sex differences in immune responses of photoperiodically entrained animals challenged against lipopolysaccharide (LPS)-induced inflammatory stress. We observed that photoperiodically entrained [short day, SD, 10?h light (L):14?h dark (D); long day, LD, 16?h L:8?h D; and natural day length, NDL, 12?h L:12?h D] male and female Indian palm squirrels, Funambulus pennanti, presented sexual dimorphism in immune status after LPS-induced stress. Females presented high humoral (anti-keyhole limpet hemocyanin immunoglobulin) and cellular immunity (lymphocyte proliferation) compared with the males of all photoperiodic conditions. Female squirrels showed reduced pro-inflammatory cytokine levels (interleukin-1β, interleukin-6, and tumor necrosis factor-α) than the males suggesting their high efficiency to recover from LPS-induced inflammatory stress. Increased duration of melatonin secretion and corticosterone concentration in squirrels experiencing SD evidently supported survival of squirrels as compared with control (NDL) and LD squirrels of both sexes. Decreased immune status in both sexes under LD condition might be due to a short melatonin signal mimicking the LDs of summer. Thus, we infer that photoperiodic entrainment via the levels of melatonin and corticosterone synergistically supported more the survival of female squirrels under LPS-induced stress.     

Executive functions and child problem behaviors are sensitive to family disruption: a study of children of mothers working overseas

Mothers in Sri Lanka are increasingly seeking overseas employment, resulting in disruption of the childcare environment. The present study was designed to evaluate the effects of maternal migration on executive function (EF) and behavior, thereby also contributing to the scientific understanding of environmental effects--or more specifically family effects--on children's neurocognitive functioning. A sample of 60 healthy 11-year-old children whose mothers had been working overseas for more than 1 year formed the study group, and a comparison group was recruited from the same schools. Evaluations were made twice over a 1-year interval with regard to the EF components inhibition and working memory as well as teacher ratings of internalizing and externalizing behavior. The children in the study group were found to have poorer EF and higher levels of externalizing behaviors. A composite score of inhibition partially mediated the group effect on externalizing behavior. Current home environment was assessed using the HOME scale, was poorer for the study group and was related to EF, but not to behavior problems. Keeping in mind the correlational nature of the present data, our results were discussed in relation to studies showing cognitive effects of stress.     

Can Capability Approach Pave the Way for Religion? A Study in the Context of Rorty’s Private/Public Sphere’s Debate

Journal of Indian Council of Philosophical Research - Rorty has been criticized for his pragmatic rationality by different thinkers like Stout, Steven carter. Here in this article our main focus is...     

Theorising the emerging green prosumer culture and profiling green prosumers in the green commodities market

This paper explores the phenomenon of green prosumption with a view to theorising the phenomenon and highlighting the challenges and opportunities this particular subculture creates for marketers of green commodities. Narratives of young green prosumers were gathered from 18 phenomenological in‐depth interviews. Capturing green prosumer experiences and subjective meanings, three thematic categories of green prosumption practices, (a) contraction, (b) control, and (c) creation, are postulated in the study. It also highlights several unforeseen challenges as well as a vast array of opportunities emerging from the three green prosumer segments identified in the study: semi‐green prosumers, empowered green prosumers, and liberated green prosumers. This study provides green commodity marketers with a set of recommendations to exploit opportunities in these largely untapped market segments.