Brain weights correlate with behavioral parameters in individual inbred mice housed in a common and enriched environment

Fifty 8-week-old Balb/c mice were individually identified and housed together in a large and enriched environment for 5 months. Maze and open field exploration, response to an aversive noise, swimming, and induced grooming tests were applied to each mouse in an initial search for possible relationships between brain morphology and spontaneous behavior in isogenic individuals living in a complex social and physical environment. The tasks generated 39 quantitative behavioral indices which include locomotion, rearing, still, and grooming bout frequencies, latencies, total, and mean bout durations. At the end of the tests, the 7-month-old mice were sacrificed and the fresh weights of their whole brain, cerebellum, brain stem, diencephalon, telencephalon, and prosencephalon were rapidly obtained. Behavioral data have wide variations and do not adjust to normal population distributions. Means of the same parameter differ between tests. A Spearman correlation matrix of all data yielded many significant correlations between indices of the same task which can be interpreted in terms of time budget and sequence probability. Significant correlations between indices of different tests suggest diverse emotionalities, exploratory strategies, and motor skills. The correlations between body and brain weights and among separate brain regions were not significant. There were several low but significant correlations between brain weights and behavioral indices. Such correlations, the resulting factors, and significant behavioral differences between mice with large and small brains suggest that mice displaying low motor activity in novel environments have larger brains and forebrain/hindbrain ratios than mice with high activity, and that animals with high scores of some specific behaviors have larger brain areas physiologically related to such behaviors.(ABSTRACT TRUNCATED AT 250 WORDS)     

The psychological cost of waiting

The study of any problem involving waiting situations invariably assumes that people dislike having to wait. The analysis of queueing problems usually prescribes that some costs should be associated with the time people spend waiting to be served. These are usually considered to be of an economic nature, though the existence of other costs of a psychological nature is accepted. It is generally accepted that after having to wait for a certain amount of time, anxiety and stress start to build up in an individual, due both to the sense of waste and the uncertainty involved in a waiting situation. This work provides a theoretical basis for analysing this building up process as it occurs during the waiting period. It is proved that, under very general conditions, the resulting psychological stress accumulated during the process is a marginal increasing function of the waiting time, and some strategies to minimise it are developed. The results obtained give theoretical support to the usual assumptions underlying the development of systems to provide “real time” information to people in waiting situations. This is especially important in the operation of public transportation systems. The results also provide theoretical support to the “convex” treatment usually given to the waiting cost function in queueing problems.     

Social structure features in three inbred strains of mice, C57Bl/6J, Balb/cj, and NIH: a comparative study

Some features of social living were investigated in three inbred strains of mice: C57Bl/6j, Balb/cj, and NIH. Five social behaviors--Aggression, Submission, Allogrooming, Social Rest and Rest Alone, as well as Wheel Running Activity--were recorded 2 h daily for a week, in 26 groups of seven male mice living in an enriched environment. Dominants and subordinates among strains shared some behavioral characteristics, but strain contributions upon social structure were also detected. Similarities among strains included the appearance of a single dominant mouse per group rated as the most aggressive, besides from being the animal presented with most Submissions. Allogrooming was more frequent among subordinates than among dominants and subordinates. Differences among strains were that agonistic behavior among subordinates was higher in the Balb/cj and NIH groups than in the C57Bl/6j mice. NIH mice were recorded in Rest Alone more often than mice from the other strains. C57Bl/6j dominants showed higher rates of Wheel Running Activity than subordinates.     

Three-dimensional perspective drawing of two-dimensional functions with microcomputers

In this paper, we present a BASIC program for Apple II series computers that allows the user to obtain perspective drawings of two-dimensional functions of known analytical expression. Also, we outline a procedure for obtaining perspective representations of two-dimensional arrays of data using the same program. The program should run on any computer with graphics mode with only slight modifications in the graphics commands.     

Maps between some different kinds of contraction function: The finite case

In some recent papers, the authors and Peter Gärdenfors have defined and studied two different kinds of formal operation, conceived as possible representations of the intuitive process of contracting a theory to eliminate a proposition. These are partial meet contraction (including as limiting cases full meet contraction and maxichoice contraction) and safe contraction. It is known, via the representation theorem for the former, that every safe contraction operation over a theory is a partial meet contraction over that theory. The purpose of the present paper is to study the relationship more finely, by seeking an explicit map between the component orderings involved in each of the two kinds of contraction. It is shown that at least in the finite case a suitable map exists, with the consequence that the relational, transitively relational, and antisymmetrically relational partial meet contraction functions form identifiable subclasses of the safe contraction functions, over any theory finite modulo logical equivalence. In the process of constructing the map, as the composition of four simple transformations, mediating notions of bottom and top contraction are introduced. The study of the infinite case remains open.     

Bilinguals in a monolingual and a bilingual speech mode: The effect on lexical access

The time course of lexical access in fluent Portuguese-English bilinguals and in English speaking monolinguals was examined during the on-line processing of spoken sentences using the phoneme-triggered lexical decision task (Blank, 1980). The bilinguals were tested in two distinct speech modes: a monolingual, English or Portuguese, speech mode, and a bilingual, code-switching, speech mode. Although the bilingual’s lexical decision response times to word targets in the monolingual speech modes were identical to those of the monolingual subjects, their response times to code-switched word targets in the bilingual mode were significantly slower. In addition, the bilinguals took longer to detect nonwords in both the monolingual and bilingual modes. These results confirm that bilinguals cannot totally deactivate their other language when in a monolingual speech mode. It is hypothesized that bilinguals search both lexicons when confronted with nonwords, even when in a totally monolingual mode, and that they search the base-language lexicon before the other lexicon when in a bilingual, code-switching, speech mode.     

Michel de Certeau's keys of political discernment in May 1968: The theological-spiritual assumptions that informed his tools of analysis

This article seeks to identify the theoretical tools that supported Michel de Certeau's political discernment during the crisis of May 1968 in France. De Certeau's ability to elucidate the novelty and complexity of this event is linked to the intertwining of his experiences as a historian, traveller (voyageur), and Christian (specifically a Jesuit). De Certeau's articulation of a 'theology of difference' allowed him to construct the intellectual and spiritual tools that enabled a lucid discernment of May 1968. Through this theology, derived from negative theology, de Certeau made the experience of faith operative at a moment of cultural crisis. The article also analyses possibilities involved in the ‘rupture’, that is, the fracture that is implied in modernity; in the notion of an event that highlights the deficiency of language, its incapacity to establish ‘a truthful communication’ in society; and the recognition of the poetic dimension of speech, which is capable of interweaving speech and action. The May 1968 event invites these elements mutually to redefine themselves.     

A review on equivalence-based procedures to teach food-portion estimation skills

This review involved a systematic analysis of equivalence-based instruction (EBI) that aimed to improve food-size interventions in diverse populations. Systematic searches identified seven studies published since 2010 that met inclusion criteria. These studies were analyzed according to their participants, design, setting, content taught, training structures, training protocol, testing format, treatment integrity, and outcomes. Results showed EBI procedures for teaching food estimation skills have been mostly implemented with adults. The type of content taught in the identified studies included carbohydrate ranges, portion size with food and non-food items, measuring cups and nutritional content of calories. Majority of included studies used one-to-many training structure and simultaneous protocols for teaching stimulus relations. Five studies completed a generalization probe and three studies reported treatment integrity data. Overall, all participants demonstrated skill acquisition of novel relations between food and portion measurement aides. Recommendations for future research and clinical applications of EBI in teaching food portion estimation are presented.