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Contrasting effects of imidacloprid on habituation in 7- and 8-day-old honeybees (Apis mellifera) 总被引:1,自引:0,他引:1
Guez D Suchail S Gauthier M Maleszka R Belzunces LP 《Neurobiology of learning and memory》2001,76(2):183-191
We examined the effects of sublethal doses (0.1, 1, and 10 ng per animal) of a new neonicotinoid insecticide, Imidacloprid, on habituation of the proboscis extension reflex (PER) in honeybees (Apis mellifera) reared under laboratory conditions. In untreated honeybees, the habituation of the proboscis extension reflex is age-dependent and there is a significant increase in the number of trials required for habituation in older bees (8-10 days old) as compared to very young bees (4-7 days old). Imidacloprid alters the number of trials needed to habituate the honeybee response to multiple sucrose stimulation. In 7-day-old bees, treatment with Imidacloprid leads to an increase in the number of trials necessary to abolish the response, whereas in 8-day-old bees, it leads to a reduction in the number of trials for habituation (15 min and 1 h after treatment), and to an increase 4 h after treatment. The temporal effects of Imidacloprid in both 7- and 8-day-old bees suggest that 4h after treatment the observed effects are due to a metabolite of Imidacloprid, rather than to Imidacloprid itself. Our results suggest the existence of two distinct subtypes of nicotinic receptors in the honeybee that have different affinities to Imidacloprid and are differentially expressed in 7- and 8-day-old individuals. 相似文献
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The following review essay explores the nature and characteristics of the fundamentalist mindset. The editors note that the fundamentalist mindset, wherever if occurs, is composed of distinct traits such as dualistic thinking, paranoia, and rage in a group context; an apocalyptic orientation that incorporates distinct perspectives on time, death, and violence; a relationship to charismatic leadership; and a totalized conversion experience. The review essay will explore these characteristics in brief, underscoring the major themes found in the authors?? exploration of fundamentalism and the psychological and historical underpinning of the pervading mindset. 相似文献
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Lindsay A. Taliaferro PhD MPH Jennifer J. Muehlenkamp PhD Joel Hetler PhD LP Glenace Edwall PhD PsyD Catherine Wright MS LPCC Anne Edwards MD Iris W. Borowsky MD PhD 《Suicide & life-threatening behavior》2013,43(3):250-261
Primary care providers were surveyed to determine how prepared they feel to address nonsuicidal self‐injury (NSSI) among adolescents, their interest in training on NSSI, and factors associated with routinely asking about NSSI when providing health supervision. Participants included family medicine physicians (n = 260), pediatricians (n = 127), family nurse practitioners (n = 96), and pediatric nurse practitioners (n = 54). Almost 50% felt unprepared to address NSSI, and over 70% wanted training in this area. Overall, relative to other areas of mental health care, clinicians felt least prepared to address and wanted more training on NSSI. Just 27% reported they routinely inquired about NSSI during health supervision. Factors associated with routinely asking about NSSI were identifying as female (OR = 2.37; 95% CI = 1.25–4.49), feeling better prepared to address NSSI (OR = 1.51; 95% CI = 1.04–2.20), and more frequently using a psychosocial interview to identify adolescents in distress (OR = 1.23; 95% CI = 1.02–1.48). Teaching clinicians to assess NSSI within a psychosocial interview may increase screening for and identification of the behavior among adolescents in primary care. 相似文献
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