Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Can sample-specific simulations help detect low base-rate taxonicity?

The authors examined the role of the sample-specific simulations (SSS; A. M. Ruscio & J. Ruscio, 2002; J. Ruscio & A. M. Ruscio, 2004) procedure in detecting low base-rate taxa that might otherwise prove elusive. The procedure preserved key distributional characteristics for moderate to high base-rate taxa, but it performed inadequately for low base-rate taxa, with low to moderate nuisance covariance, decreasing indicator validity, and increasing average nuisance covariance. Visual inspection of the curves produced by the SSS procedure, combined with the expectation that the inchworm test should produce a clear peak for low base-rate taxonic samples, led to inappropriate conclusions about the suitability of data. The authors speculate that examination of low base-rate taxa using SSS may require other algorithms for generating comparison distributions, consideration of the shape of the whole curve, and/or relaxation of the expectation that a clear peak will emerge with the inchworm test.     

A family-focused randomized controlled trial to prevent adolescent alcohol and tobacco use: The moderating roles of positive parenting and adolescent gender

Four years of longitudinal data from 2,153 families with a 5th- or 6th-grade preadolescent participating in a family-focused pediatric primary-care-based prevention program were used to examine whether prevention effects were moderated by positive parenting and/or adolescent gender. Alcohol and tobacco use, internalizing problems, and externalizing problems were examined. Although findings revealed no main effect of the prevention program, positive parenting and adolescent gender were moderators of internalizing problems and adolescent gender was a moderator of externalizing problems. Clinical implications and future directions for research are discussed.     

Empirical support for the gender‐as‐culture hypothesis.

This investigation provided a test of the gender‐as‐culture, or ‘two cultures’, hypothesis proposed by Maltz and Borker (1982) to explain male/female differences in language use. Analysis of previous empirical investigations located 16 language features that had consistently been shown to indicate communicator gender and these were tested within the framework of the four dimensions of intercultural style proposed by Gudykunst and Ting‐Toomey (1998): direct versus indirect, succinct versus elaborate, personal versus contextual and instrumental versus affective. Study 1 provided preliminary evidence supporting the hypothesized language‐feature‐by‐dimension relationships (e.g., male directives were rated more direct and female uncertainty verbs more indirect). In Study 2, respondents rated multiple exemplars of the 16 language features, as well as 16 contrasting foil sentences, on all four dimensions, finding that nearly all of the variables fell on the hypothesized intercultural dimensions. In Study 3, respondents rated four sets of naturally occurring target sentences and matching foil sentences, representing all language variables, on their appropriate intercultural dimensions in order to establish dimensional polarity. Results across the three studies supported the hypothesized language feature‐by‐stylistic dimension relationship for 15 of the 16 variables: The 6 male language features were rated as more direct, succinct, personal, and instrumental, whereas 9 of the 10 female features were perceived as more indirect, elaborate, and affective. The findings demonstrate that gender preferences for language use function in ways that are consistent with stylistic preferences that distinguish national cultures.     

Anticipatory Processing and Post‐Event Processing in Social Anxiety Disorder: An Update on the Literature

Two repetitive thinking processes that have been proposed in prominent maintenance models of social anxiety disorder (SAD) are anticipatory processing and post‐event processing. Research into these two processes has steadily increased over the last 20 years. This review highlights the main lines of existing research on anticipatory processing and post‐event processing, including studies on the nature of these processes, their association with social anxiety, the predictors, and consequences of these processes, as well as how these processes respond to treatments for SAD. The review also highlights some of the conceptual and methodological issues that have prevented the literature on anticipatory processing and post‐event processing from being more integrated and focused. Finally, the review draws together some new directions in terms of theory and research to further advance the field.     

The role of a lifetime history of oppositional defiant and conduct disorders in adults with ADHD: implications for clinical practice

IntroductionAttention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) are frequently co-occurring disorders in children and adolescents. However, their clinical status among adults is still under discussion. This study analyzes how the current clinical presentation of adult ADHD might be influenced by a lifetime history of CD and ODD. METHODS: We compared three groups of patients: ADHD without history of CD/ODD (n = 178), ADHD + history of ODD (n = 184), and ADHD + history of CD (n = 96). RESULTS: A history of CD (and to a lower extent ODD) is associated with a more severe and externalizing profile.ConclusionPast CD and ODD entail a significant negative mental health impact on persistent ADHD, reinforcing the importance of actively assessing the developmental history of adult ADHD patients.     

Knowledge-sharing intention in a virtual community: a study of participants in the Chinese Wikipedia

This study proposes a model for evaluating virtual community members' knowledge-sharing intention toward Chinese Wikipedia. The results of this study reveal that knowledge-sharing intention is influenced directly by attitude, subjective norms, and perceived behavioral control, whereas anticipated reciprocal relationships and enjoying helping are positively related to attitude; sense of self-worth and peer influences are positively related to subjective norms; and self-efficacy and resource-facilitating conditions are positively related to perceived behavioral control on knowledge sharing.     

Patterns of Sexuality Communication Between Preadolescents and Their Mothers and Fathers

The purpose of the current study was to examine communication about sexual topics between preadolescents and their mothers and fathers. Participants were 135 African-American mothers, fathers, and their 9- to 12-year-old offspring. Each member of the triad completed a 10-item measure of communication about risk factors for sexual activity, sexual communication, and sexual risk prevention. A majority of parents and their preadolescents reported communication had occurred about most topics. Mothers and fathers were equally likely to communicate with sons whereas mothers were more likely to communicate with daughters than were fathers. Based on the study results, preadolescence may be the optimal time for parents to provide sexual risk prevention messages to their children before sexual behaviors are initiated.     

Acceptability of racial microaggressions among Asian American college students: internalized model minority myth,individualism, and social conscience as correlates

ABSTRACT

How much someone finds a racial microaggression to be acceptable can vary. We focus on the acceptability of racial microaggressions among Asian American college students, in relation to cultural and religious variables. We predicted that internalized model minority stereotype and individualism will be associated with being more accepting of microaggressions. We predicted that social conscience, or the belief that the church should be active in social justice, will be associated with being less accepting of microaggressions. Results based on 102 Asian American students indicated that vertical individualism predicts greater acceptance of microaggressions, and results based on 77 Christian individuals out of the 102 participants indicated that social conscience predicts less acceptance of microaggressions. Excessive individualism may lead one to ignore the impact of racism and have a greater tolerance for microaggressions, whereas social conscience may support participation in social justice efforts, which may lead to a greater awareness of microaggressions.