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One path to human phobia may be one-trial backward fear conditioning. Human phobias transfer readily across contexts. However, animal studies of one-trial backward fear conditioning have yet to demonstrate such transfer. The present study sought to do so. It used a lick-suppression procedure with 84 naive male albino rats. Two conditioning contexts, designated O and V, were crossed factorially with two test contexts, O and V. Within each cell of the factorial design, rats received in the conditioning context either a single 12 sec tone backward paired with a single 4 sec 1 mA shock or the same tone explicitly unpaired with shock. Fear of context and fear of tone were subsequently assessed in terms of the suppression of licking that they evoked. Test results suggested that (1) the rats discriminated between contexts O and V, and (2) despite such discrimination, one-trial backward fear conditioning transferred across the two contexts. The results enhance the plausibility of one-trial backward fear conditioning as a source of human phobia.  相似文献   
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A discriminated Sidman avoidance procedure used by Forgione (1970) was replicated using a head-poke response instead of a leverpress as the avoidance operant. The resultant data were described in terms of the five dependent measures reported by Forgione. Head-poke avoidance was found to be more efficient than its leverpress counterpart and compared very favorably with the lever-disabling (or shock-timer-on) procedure used by Forgione to break up inefficient leverpress behavior patterns.  相似文献   
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There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.  相似文献   
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This article reviews the research into multimedia learning through the lens of a recently updated Handbook of Multimedia Learning edited by Richard Mayer. By examining the theories underpinning the research and the major experimental findings, a number of conclusions emerged. Firstly, the major theories and models guiding the research are well accepted and based on classical memory research, although there is a need to extend them to the affective domain. Secondly, most of the boundary conditions for effective learning from basic multimedia materials (e.g. explanatory words and pictures) have been identified. Thirdly, for more complex learning environments (e.g. games and computer‐based tutors), much less is known, and more research is required to untangle the various moderating factors. Fourthly, there is a need for further investigations that match specific instructional strategies (e.g. self‐explanations) with multimedia materials to find the most effective learning combination. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
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A simple and inexpensive method is described for the programmed presentation of pure tones of different frequencies using a single oscillator.  相似文献   
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