医生献血救人该不该罚——论卫生法律在卫生执法中的正确适用

卫生执法的根本目的是实现卫生法律的立法目的.卫生执法应当尊重卫生法律的基本精神,而不应当对卫生法律断章取义,并应当切实尊重公民的生命健康权.     

Separating cue encoding from target processing in the explicit task-cuing procedure: are there "true" task switch effects?

Six experiments were conducted to separate cue encoding from target processing in explicitly cued task switching to determine whether task switch effects could be separated from cue encoding effects and to determine the nature of the representations produced by cue encoding. Subjects were required to respond to the cue, indicating which cue was presented (Experiments 1, 3a, and 4a) or which task was cued (Experiments 2, 3b, and 4b), before performing the cued task on the target. Cue encoding was successfully separated from target processing when the cue response indicated which task was cued but not when it indicated which cue was presented. Task switch effects were found when this separation was successful, suggesting that there are "true" task switch effects independent of cue encoding. Analysis of the conditions required for successful separation suggested that cue encoding results in a semantic categorical representation of the task to be performed rather than verbal or phonological representations of individual cues. Implications for the authors' past modeling of task-switching performance are discussed.     

Physicians, Patients, and Medical Dialogue in the NYPD Blue Prostate Cancer Story

Extending literature on health information to entertainment television, we analyze the prostate cancer narrative presented in the police drama, NYPD Blue. We explain how the physician-patient interaction depicted on the show followed (and sometimes did not follow) the medical dialogue model. Findings reveal that the producers of this show advocate a more dialogic model of medical interaction. Portrayals of incompetent, ineffective physicians are contrasted with the superior, effective efforts of other physicians. The audience learns that a non-dialogic approach characterizes "bad doctors," while the dialogic method typifies "good doctors." Likewise, medical professionals can use such texts to enhance physician-patient interaction.     

Parental and family predictors of behavior problems in inner-city black children

Studied contributions of maternal psychological distress, family stress load, maternal and family risk factors, and family coping strategies in predicting behavior problems in 441 inner-city black primary-grade children. Results indicated maternal psychological distress and high family stress load were associated with high child behavior problems. Family coping strategies offered no protection against risk, while coping with life difficulties by reframing them was detrimental to child behavioral adjustment. Active help-seeking strategies (i.e., family mobilization, acquiring social supports) served to moderate the effects of maternal psychological distress and family risk attributes for boys, but exacerbated the effects of dysfunctional maternal social and psychiatric histories for girls. Implications for understanding vulnerability and resilience in inner-city black children and recommendations for future research are discussed.     

Correlation between Changes in Stress-Induced Corticosterone Secretion and GR mRNA Levels

The current study was conducted to determine the potential relationship between stress-induced corticosterone secretion and corticosteroid receptor mRNA levels after 5 days of intermittent stress. In particular, we were interested in the rate at which animals terminate a stress response, and how this termination may be altered by repeated stress. Adult male Sprague-Dawley rats were subjected to either 5 days of restraint stress or 5 days of an unpredictable stress paradigm. Restraint-stress induced corticosterone secretion was measured on Days 1 and 5 in both groups, and animals were killed on Day 6. Glucocorticoid receptor (GR), and mineralocorticoid (MR) mRNA levels were determined using in-situ hybridization techniques. Five days of restraint stress caused an habituation of the plasma corticosterone response to stress measured 60 and 90 min post-stress initiation; this pattern of corticosterone secretion was not observed in the animals subjected to unpredictable stress. Five days of either stress paradigm did not alter MR mRNA levels measured within the hippocampus or GR mRNA levels within the hippocampus or the medial parvocellular division of the paraventricular nucleus of the hypothalamus (mpPVN). However, an individual's GR mRNA levels measured within the CA1/2 region of the hippocampus and the mpPVN were significantly correlated with the degree of habituation of the corticosterone response to stress measured on Day 5. This suggests that an increase in the rate of termination of the stress response and levels of GR within the hippocampus and mpPVN may be functionally related.     

Color onsets and offsets, and luminance changes can cause change blindness

It has recently been demonstrated that people often fail to detect between-view changes in their visual environment. This phenomenon, called 'change blindness' (CB), occurs whenever the perceptual transient that usually accompanies a change is somehow blocked, or made less salient. In the well-known flicker paradigm, the transient is blocked by inserting a blank screen between the original and changed scenes. We tested whether transients that do not involve the appearance or disappearance of visual objects would also produce CB. Therefore we tested whether the appearance or disappearance of color information, and increments or decrements in luminance, could cause CB. In three experiments, subjects searched for changes in natural scenes. We found that both color transients and luminance transients significantly reduced change detection (by approximately 30%) relative to a no-transient condition.     

Episodic and semantic components of the compound-stimulus strategy in the explicit task-cuing procedure

The explicit task-cuing procedure is commonly used to study executive control processes involved in set switching, but performance in this task-switching procedure may be accomplished without switching tasks. Subjects may perform both tasks by using a compound-stimulus strategy, in which subjects encode the cue, encode the target, and use the combination as a compound retrieval cue to choose the appropriate response. We manipulated the number of targets (8, 16,32, or 640) that subjects experienced in a four-cue/two-task procedure to separate episodic and semantic memory retrieval components of the compound-stimulus strategy. Cue repetitions were faster than task repetitions, and task repetitions were only slightly faster than task alternations, suggesting that cue repetition effects account for the bulk of the difference between repetitions and alternations. We found the same effects with all target set sizes. The results are consistent with use of a semantic compound-stimulus strategy.     

The cost of a voluntary task switch

Task-switching paradigms are widely used to study executive control. However, standard paradigms may not require active control to switch tasks. We examined voluntary task switching by having subjects choose which task to perform on a series of bivalent stimuli. Subjects performed parity or magnitude judgments on single digits. Instructions were to perform the two tasks equally often and in a random order. The response-to-stimulus interval (RSI) was either 100 or 1,000 ms, manipulated between blocks. Task alternations were slower than task repetitions, and this switch cost was greater at the short RSI than at the long RSI (310 and 94 ms, respectively). Additionally, subjects produced more task repetitions than expected if the tasks were performed in a random sequence. These results show costs associated with a voluntary task switch, when subjects must actively control the choice of the task to be performed.     

高风险婴儿前瞻性纵向研究与孤独症谱系障碍早期识别

孤独症谱系障碍(Autism Spectrum Disorder, ASD)早期识别有助于早期诊断和早期干预的实施, 对于改善ASD儿童发育结果至关重要。高风险前瞻性纵向研究以高风险婴儿(ASD儿童的年幼同胞, 入组年龄小于12个月)作为主要研究对象, 通过对ASD高风险婴儿(24至36个月之间诊断为ASD的高风险婴儿)的早期发育轨迹的描绘和核心症状早期表现的识别, 为ASD早期识别提供了重要依据。未来可以增加被试数量、延长观察时间并密集观察时间点、关注伴发障碍、综合考虑遗传、环境和文化因素影响, 并结合早期干预研究进行深入探索。未来在中国开展相关研究具有重要的科学价值和临床意义。