Conflict of interest and its significance in science and medicine Warsaw,Poland, 5–6 April, 2002

This article summarizes the April 5–6, 2002 conference on Conflict of Interest and Its Significance in Science and Medicine. Several themes are identified and addressed, including the globalization of science, the widespread presence of conflicts, the increased interest and involvement in conflict of interest by a number of organizations, the difference between academic research and research conducted by industry, and the tension between science and medicine. At the heart of the matter lies objectivity in research and the need for transparency to ensure objectivity. Several future activities were discussed, including the need to share specific examples of how conflict has been managed, and the need for behavioral research to provide a sound empirical understanding of the best ways to provide informed consent for research subjects. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002.     

Conflict of interest in medical research in Estonia

An area where conflicts of interest can take place in Estonia is in the conduct of clinical trials. The paper lists the main areas where such conflicts of interest can occur. The author also briefly discusses Estonia’s current position with regard to regulating genetic information and the commencement of the Estonian Genome Project. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002.     

Conflict of interest and its significance in science and medicine: a view from Eastern Europe

Conclusions  Continued scientific and medical progress in Central and Eastern Europe depends on the development of an atmosphere that is conducive to implementing the changes that are necessary to bring better health and longer lives for everyone. Privatization and commercialization are threatening the objectivity of clinical research and the availability of health care because uncontrolled market mechanisms focused on profit are nurturing conflict of interest that generate bias and unreliability into research and medicine. Changes are needed that address the following:

Gaze behavior when approaching an intersection: Dwell time distribution and comparison with a quantitative prediction

The allocation of overt visual attention is investigated in a multi-task and dynamical situation: driving. The Expectancy–Value model of attention allocation stipulates that visual exploration depends on the expectancy and the value of the task-related information available in each Area Of Interest (AOI). We consider the approach to an intersection as a multi-task situation where two subtasks are involved: vehicle control and interactions with other drivers. Each of these subtasks is associated with some specific visual information present in the associated AOIs: the driver’s lane and the intersecting road at the intersection. An experiment was conducted in a driving simulator, coupled with a head-mounted eye-tracker. The intersecting road’s AOI’s Expectancy was manipulated with the traffic density, and its Value was manipulated with the priority rule before the intersection (stop, yield, and priority). The distribution of visual attention and the dynamics of visual exploration were analyzed on 20 participants, taking into account the dwell time in the AOIs associated to the driving subtasks, and the gaze transitions between the AOIs. The results suggest that visual attention to intersecting roads varied with the priority rule, and impacted the visual attention associated with the vehicle control subtask. In addition, a quantitative model was used to improve the understanding of the Expectancy and Value factors. The comparison of the data with the model’s predictions enables quantifying the observed differences between the experimental factors. Finally, the results associated with the traffic density are discussed in relation to the nature of the relevant information while approaching the intersection.     

Predicting Behavioral Career Commitment of College Students With Attachment and Separation Relationships

This study compares the behavioral and attitudinal career commitment of college students, then examines the influences of parental attachment and separation on career commitment. Undergraduates (N = 195) from 3 academic programs were surveyed: a combined degree program that accepts students simultaneously into bachelor's and medical programs, premedical curriculum alone, and general university enrollment. Behavioral career commitment (enrollment in one of the aforementioned programs) correlated with attitudinal commitment for the combined degree and general enrollment groups. Greater attachment to father and less separation from parents were associated with lower career commitment for men. Attachment and separation did not predict career commitment for women.     

Consumer Perspectives of Participation in Vocational Programs by Individuals With Serious Mental Illness: Two Phenomenological Studies

Engagement in worker roles presents significant challenges for individuals with serious mental illnesses. Evolution of vocational rehabilitation programs has yielded evidence-based support for supported employment models. This research presents a phenomenological study of consumer viewpoints concerning participation in earlier vocational rehabilitation programs, followed by a study of supported employment participation perspectives. Initial study themes of Chaos: Living with Disruptions, Mixed Blessings: Vocational Rehabilitation Program, Feelings of Discrepancy, and Searching for Order were reinforced by follow-up study themes of Positive Feelings of Worker Satisfaction and Managing Self/Illness. Consumers identified success in employment outcomes, if able to balance illness and work demands.     

Novel object detection and recognition system based on points of interest selection and SVM classification

Due to the progression in computer vision technology, object recognition systems have gained considerable research interest. Though there are numerous object recognition systems in the literature, there is always a constant demand for better object recognition systems. Taking this as a challenge, this work proposes a novel object recognition system based on points of interest and feature extraction. Initially, the points of interest of the image are selected by means of Derivative Kadir-Brady (DKB) detector and the neighbourhood pixels of a particular window size are selected for further processing. The gabor and curvelet features are extracted from the area of interest, followed by the Support Vector Machine (SVM) classification. The performance of the proposed object recognition system is evaluated against three analogous techniques in terms of accuracy, precision, recall and F-measure. On experimental analysis, it is proven that the proposed approach outperforms the existing approaches and the performance of the proposed work is satisfactory.     

Does multitasking mediate the relationships between episodic memory,attention, executive functions and apathetic manifestations in traumatic brain injury?

Apathy is frequently described in patients with traumatic brain injury (TBI); its negative consequences particularly affect functional independence. Among apathetic manifestations, lack of initiative and lack of interest have mainly been associated with cognitive impairments. However, few studies have been conducted to precisely identify the underlying cognitive processes. Our aims were (1) to determine the best predictor of apathy from among several cognitive processes, including episodic memory and attention/executive mechanisms and multitasking, and (2) to examine to what extent multitasking could mediate the relationships between specific cognitive processes and lack of initiative/interest. Seventy participants (34 patients with TBI matched with 36 control participants) were given a questionnaire to assess anxio‐depressive symptoms, four tasks to assess specific cognitive processes, and one task to assess real‐life multitasking. Participants’ relatives completed an apathy questionnaire. Multitasking, as assessed by the number of goals not achieved, was the only significant predictor of apathetic manifestations. In addition, the mediation analyses revealed that multitasking performance mediated the relationships between verbal episodic memory and lack of initiative/interest, whereas executive and attentional functions were only indirectly related to lack of initiative/interest due to their significant impacts on multitasking. These results shed new light on the aetiology of apathetic manifestations in patients with TBI, indicating how specific cognitive deficits are expressed in real‐life multitasking, and consequently, how they may lead to the development and/or maintenance of apathetic manifestations.     

小学低年级儿童的计算流畅性与数学焦虑:基于变量为中心与个体为中心的分析

为考察计算流畅性对小学低年级儿童数学焦虑的影响及作用机制,对592名小学二年级儿童的计算流畅性、数学学习兴趣、教师支持和数学焦虑进行测查。结果发现:(1)计算流畅性不仅通过数学学习兴趣间接影响数学焦虑,也可通过数学学习兴趣进而通过教师支持间接影响数学焦虑;(2)对计算流畅性和数学学习兴趣得分进行潜剖面分析,可将儿童区分为三种类型:低能力-低兴趣型、高能力-高兴趣型和低能力-高兴趣型;(3)低能力-低兴趣型儿童的数学焦虑得分显著高于其他两类,而低能力-高兴趣型和高能力-高兴趣型儿童的数学焦虑得分则无显著差异。上述结果表明计算流畅性、数学学习兴趣和教师支持在预防和干预小学低年级儿童的数学焦虑中具有重要作用。     

大学生职业成熟度研究

本文对台湾学者的职业成熟度问卷进行了修订。结果显示经修订得到的大学生职业成熟度问卷具有较好的信度、效度,可以作为我国大学生职业成熟度的测量工具。