乳腺癌保乳治疗的进展与临床选择

保乳治疗既能满足乳腺癌的治疗要求,又适于追求更高的生活质量,但应用时必须严格掌握适应证,还要充分考虑到病人及其家庭的经济和心理承受能力,医院的综合治疗条件等因素,充分做到科学性与人性化的高度结合,才能获得最佳临床效果。     

A randomized trial of employment-based reinforcement of cocaine abstinence in injection drug users

High-magnitude and long-duration abstinence reinforcement can promote drug abstinence but can be difficult to finance. Employment may be a vehicle for arranging high-magnitude and long-duration abstinence reinforcement. This study determined if employment-based abstinence reinforcement could increase cocaine abstinence in adults who inject drugs and use cocaine during methadone treatment. Participants could work 4 hr every weekday in a workplace where they could earn about $10.00 per hour in vouchers; they were required to provide routine urine samples. Participants who attended the workplace and provided cocaine-positive urine samples during the initial 4 weeks were invited to work 26 weeks and were randomly assigned to an abstinence-and-work (n = 28) or work-only (n = 28) group. Abstinence-and-work participants had to provide urine samples showing cocaine abstinence to work and maintain maximum pay. Work-only participants could work independent of their urinalysis results. Abstinence-and-work participants provided more (p = .004; OR = 5.80, 95% CI = 2.03-16.56) cocaine-negative urine samples (29%) than did work-only participants (10%). Employment-based abstinence reinforcement can increase cocaine abstinence.     

Evidence Based Treatments for Bipolar Disorder in Children and Adolescents

Limited research has been devoted to developing and testing psychosocial treatments for bipolar disorder (BPD) in children and adolescents, a chronic and impairing mental illness that has received increased attention in recent years. Existing treatments are intended as adjuncts to medication, and share a family-based psychoeducation approach. Components of four treatments are discussed: family-focused treatment (FFT), the RAINBOW Program, multi-family psychoeducation groups (MFPG), and individual family psychoeducation (IFP). Evidence supporting each approach is detailed. Selected components of MFPG are described. A flowchart provides suggestions for sequencing interventions to maximize effectiveness. To illustrate the use of evidence-based treatment for children with BPD, a case example is provided.

Theoretical and research support for the Duluth Model: A reply to dutton and corvo

In a recent article, Dutton and Corvo denounce and reject the so-called Duluth Model of batterer intervention based on cognitive–behavioral counseling, reinforcement from the criminal justice system, and coordination of additional community services. They not only accuse it of being ineffective and detrimental to progress in the field, but assert that its supporters are merely acting out of ideological and activist motivations. These authors call for research-based treatment that is more psycho-therapeutic in nature, along with a diminished role of the criminal justice system and more attention to women's violence. The authors, however, are highly selective in the research they use to substantiate their position and apply their own activist biases to its interpretation. Their portrayal of the Duluth Model, and the fundamentals it represents, is a distorted caricature of its current conception. There is psychological theory and criminal justice research that support the Duluth Model and its utility. Moreover, developments in the field contradict the claims that the Duluth Model has an “iron-clad” hold that is impeding progress. The categorical condemnations in the Dutton and Corvo article shut-off needed dialogue and debate rather than further those developments.     

Parental Refusal of Medical Treatment for a Newborn

Theoretical Medicine and Bioethics - When there is a conflict between parents and the physician over appropriate care due to an infant whose decision prevails? What standard, if any, should guide...     

Relationships between personal beliefs and treatment acceptability, and preferences for behavioral treatments

Background

The literature on preferences for behavioral interventions is limited in terms of understanding treatment-related factors that underlie treatment choice. The objectives of this study were to examine the direct relationships between personal beliefs about clinical condition, perception of treatment acceptability, and preferences for behavioral interventions for insomnia.

Methods

The data set used in this study was obtained from 431 persons with insomnia who participated in a partially randomized clinical trial and expressed preferences for treatment options. The data were collected at baseline. Logistic regression was used to examine the relationships between personal beliefs and treatment acceptability, and preferences. The relationships between personal beliefs and perception of treatment acceptability were explored with correlational analysis.

Results

Perception of treatment acceptability was associated with preferences. Persons viewing the option as convenient tended to choose that option for managing insomnia. Personal beliefs were not related to preferences. However, beliefs about sleep promoting behaviors were correlated with perceived treatment effectiveness.

Conclusions

Perception of treatment acceptability underlies expressed preferences for behavioral interventions. Personal beliefs about insomnia are not directly associated with preferences. Importance is highlighted for providing information about treatment options and exploring perception of each option's acceptability during the process of treatment selection.     

The Sequential Combination of Pharmacotherapy and Psychotherapy in Mood Disorders

The aim of this review was to consider the literature concerned with a sequential use of pharmacotherapy and psychotherapy in mood disorders. Review of the clinical trials where treatment components were used in a sequential order were identified by using MEDLINE, a manual search of the literature and the Index Medicus. In unipolar recurrent depression, the sequential use of pharmacotherapy and psychotherapy was found to improve relapse rate. In bipolar disorder, the use of psychotherapeutic strategies in patients who were already assuming mood stabilizers was also found to yield clinical benefits. The sequential model has the potential for improving the logic and timing of interventions. A conceptual shift in current assessment methods (staging) is needed.     

Evaluating Pastoral Effectiveness: To Measure or Not to Measure

Interviews were conducted with 101 senior pastoral leaders from a variety of denominations in order to identify the ways in which pastors and those in authority positions over senior pastoral leaders measure their own effectiveness. The findings of these interviews revealed 23 measures of effectiveness in five categories, including leader outcomes, congregational outcomes, and objective outcomes. Based on the effectiveness taxonomy described in the current study, a process is suggested for a preliminary discussion among church leadership teams, congregational boards, and denominations to identify their primary mission, constituencies served, and related effectiveness priorities.     

老年非小细胞肺癌治疗中存在的问题

肺癌已成为危害人类健康和导致死亡的最主要疾病,其中一半以上发生在老年人,且大部分为确诊时已为晚期,针对这些患者的诊断和治疗还存在很多误区,因多病并发所致的诊断延误、因恐惧所致的逃避、以及因对药物的过度依赖而对患者心理因素的忽视等,致使部分老年肺癌患者不能及时得到合理的治疗,值得引起临床医师的重视。     

盆腔炎性疾病的诊断和治疗

盆腔炎性疾病（pelvic inflammatory disease,PID）是指女性上生殖道的一组感染性疾病,由于临床不典型和致病微生物的多样性,导致目前临床上PID的诊断和治疗有一定的难度。本文介绍PID发病机制、高危因素、后遗症和并发症等方面的研究进展,推荐其诊断和治疗的最新规范。