Spatial reasoning with external visualizations: what matters is what you see, not whether you interact

Three experiments examined the effects of interactive visualizations and spatial abilities on a task requiring participants to infer and draw cross sections of a three-dimensional (3D) object. The experiments manipulated whether participants could interactively control a virtual 3D visualization of the object while performing the task, and compared participants who were allowed interactive control of the visualization to those who were not allowed control. In Experiment 1, interactivity produced better performance than passive viewing, but the advantage of interactivity disappeared in Experiment 2 when visual input for the two conditions in a yoked design was equalized. In Experiments 2 and 3, differences in how interactive participants manipulated the visualization were large and related to performance. In Experiment 3, non-interactive participants who watched optimal movements of the display performed as well as interactive participants who manipulated the visualization effectively and better than interactive participants who manipulated the visualization ineffectively. Spatial ability made an independent contribution to performance on the spatial reasoning task, but did not predict patterns of interactive behavior. These experiments indicate that providing participants with active control of a computer visualization does not necessarily enhance task performance, whereas seeing the most task-relevant information does, and this is true regardless of whether the task-relevant information is obtained actively or passively.     

Modeling how, when, and what is learned in a simple fault-finding task

We have developed a process model that learns in multiple ways while finding faults in a simple control panel device. The model predicts human participants' learning through its own learning. The model's performance was systematically compared to human learning data, including the time course and specific sequence of learned behaviors. These comparisons show that the model accounts very well for measures such as problem-solving strategy, the relative difficulty of faults, and average fault-finding time. More important, because the model learns and transfers its learning across problems, it also accounts for the faster problem-solving times due to learning when examined across participants, across faults, and across the series of 20 trials on an individual participant basis. The model shows how learning while problem solving can lead to more recognition-based performance, and helps explain how the shape of the learning curve can arise through learning and be modified by differential transfer. Overall, the quality of the correspondence appears to have arisen from procedural, declarative, and episodic learning all taking place within individual problem-solving episodes.     

Profiles of competence and adaptation in preschoolers as related to the quality of parent–child interaction

In a sample of 107 five-year-olds, cluster analysis was used to identify groups of children with similar profiles of competence and adaptation. A comprehensive set of child characteristics was included in the analysis, together covering the most important aspects of five-year-olds’ development and functioning. Three groups of children emerged, which were labeled Well-adapted/Competent, Underachieving/Internalizing, and Maladapted/Externalizing. Well-adapted/Competent children (59%) were competent and well-adjusted in all domains. The Maladapted/Externalizing children (22%) scored low in almost all domains of competence and functioning, and the Underachieving/Internalizing children (22%) showed a mixed profile of competence and adaptation. The differences in the quality of parent–child interaction that were observed between the groups provide clues as to how the different profiles of competence and adaptation are shaped and maintained in the interactions with parents.     

急性冠脉综合征（ACS）使用他汀类药物越早越好

通过对急性冠脉综合征他汀治疗的循证医学证据分析,探讨他汀类药物治疗越早越好的依据,并分析血脂治疗达标现状,提高高危、极高危患者的血脂治疗达标率。汇总急性冠脉综合征的他汀治疗相关研究：MIRCAL、PROVEIT、ARMYDA等,以及他汀治疗对斑块的研究ES-TABLISH、GAIN等试验的研究结果,分析美国胆固醇教育计划中血脂目标,以及中国成人血脂异常防治指南中血脂目标值,结合目前临床血脂达标现状,用以确定高危、极高危患者使用他汀治疗的方案应越早越好。心内科以及其他科室的医生应该积极按照《指南》要求尽早使用他汀类药物。     

稳定性冠心病何时需要PCI

目前稳定性冠心病通行的治疗策略是药物治疗的同时常规作冠脉造影,如果病变严重,则尽可能地作介入治疗。但最近COURAGE试验结果的公布,证实介入治疗仅可以缓解症状,但不能改善预后。因此,我们要对PCI在稳定性冠心病中的作用和定位重新进行思考。     

腹腔肿块外科处理的临床决策

临床经常会面对诊断、来源、性质不清的腹腔内肿块。腹腔内肿块是临床常见的病症之一,大多需要外科手术。如何合理应对、妥善处置、科学决策是临床医师对本病诊治的要求和不懈追求。诊断的过程中,依靠详尽的病史、细致的体格检查、恰当的辅助检查,并进行综合的分析以及逻辑思维,做出正确的鉴别和诊断,以解决是否为腹腔内肿块;而后,尽快确定肿块的部位及性质,确定处理的方法和原则,制订详尽的手术方案和步骤。     

儿童牙病诊疗中的人文关怀

通过对儿童心理特点和引起儿童牙科畏惧症原因的分析,提出儿童牙病治疗过程中人文关怀的措施,体现在诊疗环境的改善,无痛技术的应用,患儿诊疗前、中、后的心理干预以及医务人员综合能力和素质的培养等方面,将对患儿身心健康的关爱,渗透于口腔疾病诊治的全过程。     

Livin在小细胞肺癌中的表达及与Caspase-3相关性研究

为了探讨Livin蛋白在小细胞肺癌（SCLC）组织中的表达及与Caspase-3的关系,我们使用免疫组化法检测Livin和Caspase-3在30例SCLC及癌旁肺组织中的表达。结果显示,Livin在SCLC中表达明显高于正常组织（P〈0．01）,与TNM分期、淋巴结转移和肿瘤大小无关。Caspase-3在SCLC组织中表达明显下降（P〈0．01）,与Livin表达呈负相关。因此,Livin与Caspase-3的异常表达可能在SCLC癌变中起协调作用,并有望成为诊断和基因治疗的新靶点。     

子宫肌瘤治疗策略

目前在有些医院对子宫肌瘤的治疗有过治、滥治的趋势,亟待统一认识、规范管理、明确治疗原则。本文将围绕子宫肌瘤该不该治疗,该不该手术,该不该切除子宫进行探讨,重点介绍手术、药物、介入及物理消融术等各种方法治疗子宫肌瘤的最新进展。     

对子宫肌瘤患者从医心理及治疗决策的思考

子宫肌瘤是妇科最常见的良性肿瘤,发病率高、恶变率低,目前治疗方法较多,但各有利弊;众多子宫肌瘤患者从医心理复杂,甚至难以配合治疗,医生应针对不同部位、大小、症状的肌瘤及患者的不同年龄、生育需求和心理状态,制定出个体化、人性化治疗方案,以期取得患者机体和心理均满意的和谐疗效。