关于血管紧张素转换酶抑制药＋β受体阻断药组合的重新审视

采取联合用药方案治疗高血压已成为近年来临床用药的总体趋势。临床用药情况调查结果表明,血管紧张素转换酶抑制药＋β受体阻断药的联合用药组合占有一定的使用率,分析两类药的降压作用以及对高血压常见并发症和对代谢、心率等的影响,可见这个组合是合理的。     

What difference does counselling make? – The perceptions of drug‐using clients on low incomes

Context: This paper reports on a qualitative study looking at the perceptions of clients who use drugs and are on low income. Research suggests that counselling services can experience difficulties in reaching and retaining such clients, and outcomes of counselling can be disappointing. Aim: To learn from clients who had engaged in counselling for over six months what difference it had made to their lives. Method: Grounded theory methodology was used to analyse semi‐structured interviews with six participants. Findings: Findings included changes in the clients’ internal world, their connectedness with society, their familiarity with counselling, and their perception of the relationship with the counsellor. Factors within the counselling process which helped and hindered change were identified. The study documents how participants were able to use counselling to improve their lives.     

Outcome expectations and use of smokeless tobacco (snus): A cross‐sectional study among young Norwegian snus users

Wiium, N. & Aarø, L.E. (2011). Outcome expectations and use of smokeless tobacco (snus): A cross‐sectional study among young Norwegian snus users. Scandinavian Journal of Psychology 52, 64–70. In this study, measures of outcome expectancies related to use of snus (wet snuff) were used to predict reported frequency of snus use. Data stem from a nation‐wide survey in Norway among 16‐ to 20‐year‐olds. Only users of snus were included in the statistical analyses (n = 589). The main outcome measure, frequency of snus use, was measured as a categorical variable – occasional, weekly and daily use. Four dimensions of outcome expectancies (mood regulation, smoking control, weight control and negative health outcomes) were measured and confirmed in a confirmatory factor analysis. Informants tended to believe that snus use is harmful to health, but still they supported the idea of snus as a way to control own cigarette smoking. In a SEM model, two of the four dimensions of outcome expectancies turned out to be particularly significant predictors of frequency of snus use – mood regulation and smoking control. No significant interactions with gender were found. Males scored higher than females on “mood regulation”, and “smoking control”, while females scored higher than males on “negative health outcomes”. If more smokers were convinced that snus use is a less harmful alternative, more of them might start using snus, not only because there is some association between health outcome expectancies and snus use, but also because snus use by many is perceived as a remedy to stop smoking and as a way to gain some of the mood regulation benefits which are usually associated with smoking.     

Text messaging, personality, and the social context

The purpose of this research was to undertake some analyses of how the language used in text messaging varies as a function of personality traits and the interpersonal context. After completing personality questionnaires, participants provided their most recent text messages and indicated their relationship with the message recipient on several dimensions. Correlations between Linguistic Inquiry and Word Count (LIWC) categories and personality traits and relationship status were examined. There were significant correlations between certain LIWC categories and extraversion (e.g., personal pronouns), neuroticism (e.g., negative emotion words) and agreeableness (e.g., positive emotion words), suggesting that personality traits are displayed in how one texts. One of the defining features of texting - linguistic alterations (e.g., abbreviations) - varied as a function of both personality traits and relationship status. Overall, the results provide a snapshot of what text messages look like, and how they reflect the texter’s personality and the interpersonal context.     

Developmental associations between externalizing behaviors, peer delinquency, drug use, perceived neighborhood crime, and violent behavior in urban communities

This study examines the precursors of violent behavior among urban, racial/ethnic minority adults. Data are from an on-going study of male and female African Americans and Puerto Ricans, interviewed at four time waves, Time 1-Time 4 (T1-T4), from adolescence to adulthood. Structural Equation Modeling was used to analyze the developmental pathways, beginning in mid-adolescence (T1; age = 14.0 years), to violent behavior in adulthood (T4; age = 29.2 years). The variables assessed were: components of externalizing behaviors (i.e., rebelliousness, delinquency; T1, T3); illicit drug use (T2); peer delinquency (T2); perceived neighborhood crime (T4); and violent behavior (T3, T4). Results showed that the participants' externalizing behaviors (rebelliousness and delinquency) were relatively stable from mid-adolescence (T1; age = 14.0 years) to early adulthood (T3; age = 24.4 years). The participants' externalizing behaviors in mid-adolescence also had a direct pathway to peer delinquency in late adolescence (T2; age = 19.1 years). Peer delinquency, in turn, had a direct pathway to the participants' illicit drug use in late adolescence (T2), and to externalizing behaviors in early adulthood (T3). The participants' illicit drug use (T2; age = 19.1 years) had both direct and indirect paths to violent behavior in adulthood (T4). The participants' externalizing behaviors in early adulthood (T3) were linked with violent behavior at T3, and perceived neighborhood crime (T4), both of which had direct pathways to violent behavior in adulthood (T4). The findings suggest developmental periods during which externalizing behaviors, exposure to delinquent peers, illegal drug use, and neighborhood crime could be targeted by prevention and intervention programs in order to reduce violent behavior.     

青少年疏离感与病理性互联网使用的关系：家庭功能和同伴接纳的调节效应检验

通过对549名初一至高二年级城市青少年的问卷调查, 考察了青少年病理性互联网使用的特点及其与疏离感之间的关系, 并对家庭功能和同伴接纳是否可以调节疏离感与病理性互联网使用之间的关系进行了检验。结果发现：(1)在所有使用互联网的青少年被试中, 网络成瘾群体的检出率为8.93%; (2)女青少年病理性互联网使用的突显性水平高于男青少年。在病理性互联网使用的消极后果上, 初一青少年高于高一、初三和高二青少年。但青少年病理性互联网使用总体上不存在显著的性别和年级差异; (3)疏离感较高的青少年病理性互联网使用的水平也较高, 健康的家庭功能可以保护疏离感高的青少年减少病理性互联网使用, 但同伴接纳对高疏离感青少年减少病理性互联网使用不具有保护性作用。     

Community-Based Prevention Support: Using the Interactive Systems Framework to Facilitate Grassroots Evidenced-Based Substance Abuse Prevention

The community plays an important role in the success of substance abuse prevention efforts. However, current funding structures and a focus on limited approaches to prevention delivery have created a large gap between what substance abuse prevention professionals practice and what the community at large knows about prevention. The concept of “community” has not always been well‐defined in the field of prevention, and there are few mechanisms to engage grassroots community members in evidence‐based substance abuse prevention. This article explains how Wandersman et al.'s (Am J Community Psychol 41:171–181, 2008) Interactive Systems Framework can be applied to grassroots prevention efforts. The authors describe a Community Prevention Support System that collaborates with the Professional Prevention Support System to promote the adoption of evidence‐based substance abuse prevention practices at the grassroots, community level. Special Issue: Advances in Bridging Research and Practice Using the Interactive System Framework for Dissemination and Implementation; Guest Editors: Abraham Wandersman, Paul Flaspohler, Catherine A. Lesesne, Richard Puddy; Action Editor: Emilie Phillips Smith     

Choosing and using tools: Prior experience and task difficulty influence preschoolers’ tool-use strategies

Children's acquisition of tool use abilities is an important part of development but is not yet well understood. This study compares two modes of tool-use learning, observation and individual haptic experience. Two- and 3-year-olds had haptic experience with tools, observed tool use by others, had both haptic and observational experience, or no tool exposure. Their tool choice and use were evaluated across six problem-solving tasks that varied in degree of difficulty. Children learned about tools better by observation than by individual learning through manual exploration. Performance also varied by task difficulty, with more complex tasks proving more difficult. Findings are discussed from cognitive and evolutionary perspectives.     

Health Behaviors of Childhood Cancer Survivors: What We’ve Learned

There has been a dramatic increase in the number of childhood cancer survivors due to improved cancer treatments. However, these survivors are at risk for numerous late-effects as a result of their cancer therapy. Engaging in health-protective behaviors and limiting risky health behaviors are vitally important for survivors given their increased risks and physical late-effects. For this paper, we systematically reviewed the literature on childhood cancer survivors’ health behaviors by searching for published data and conference proceedings using computerized databases and references, and summarized these results. We examined the literature describing the prevalence of a variety of health behaviors among survivors, identifying significant covariates, and describing health behavior interventions. Finally, we provided research recommendations and discussed an ongoing study designed to address some of the limitations in the existing literature. The research to date is limited and recommendations for future studies are outlined.