Mapping people's positions regarding the acceptability of somatic gene therapy

IntroductionAs gene therapy entails potential drawbacks, studies are needed in order to know people's opinions regarding its use.ObjectivesThe present study examined French people's positions regarding somatic gene therapy.MethodA sample of 224 adults living in various areas in France was presented with 32 realistic scenarios that were created by orthogonally combining the levels of four factors: the type of illness (e.g., hemophilia), the probability of transmission of the pathogenic gene, the technique used (e.g., transfer of a functional gene just after birth), and le probability of success of the therapy.ResultsThrough cluster analysis, six qualitatively different positions were found: Never very acceptable (8% of the sample, mostly males and more educated people), Legalist (17%, mostly people who have been informed of the legal and technical aspects of the therapy), Depends on the chances of success (18%), Fully acceptable after birth (5%), Fully acceptable before birth (8%), and Quite always acceptable (33%, mostly older people with children).ConclusionAlthough it has some few detractors, the recourse to gene therapy seems to be well accepted by a majority of the participants, and this high level of acceptation hold whether the pathology considered is hemophilia, immunodeficiency, propensity to develop cancer, or cardiovascular pathology.     

辩证行为疗法：理论背景、治疗效果及作用机制

辨证行为疗法（Dialectical Behavior Therapy, DBT）于20世纪90年代初由美国治疗师Linehan创立。作为第三代行为治疗之一,该疗法以行为主义理论、辩证哲学、生物社会理论及禅宗为哲学基础,通过增加患者的技能使用,提高其情绪调节能力,以达到治疗目的。临床研究已证明其在边缘人格障碍,自杀及自伤行为中具有良好的治疗效果,除此之外也广泛适用于其他心理障碍及群体。DBT的临床效果、改变机制及拓展应用都需进一步研究。     

正式反馈的发展与临床应用

摘要:正式反馈通过系统收集当事人的效果反馈来追踪其治疗进展,进而识别缺乏治疗进展的个案,并通过促进治疗策略的调整来阻止治疗失败。正式反馈是近20年来发展出的一种循证治疗手段,其目的为进一步提高当事人的咨询效果。正式反馈的发展大致经历了临床有效性检验和实用性发展两个阶段。正式反馈可用于促进个体、夫妻和团体咨询的效果,也可用于评估临床督导效果、确定督导个案和指导临床督导。未来研究可探讨咨询师对待正式反馈的态度,拓展正式反馈的使用价值,建立正式反馈系统的本土化常模。     

Comparison of contingent and noncontingent access to therapy dogs during academic tasks in children with autism spectrum disorder

This study compared contingent and noncontingent access to therapy dogs during educational tasks for children with autism spectrum disorder using a multielement design. The experimenters assessed whether initial preference for the dog predicted reinforcer efficacy and how preference changed across time. A higher response rate during contingent dog sessions than baseline sessions occurred for 4 out of 5 participants, suggesting that the dog functioned as a reinforcer. One participant engaged in a high rate of responding in both contingent and noncontingent dog conditions. Preference assessments revealed idiosyncrasies, suggesting that further research is needed into the predictive nature of initial preference assessments with animals as part of the stimulus array. The experimenters also analyzed salivary cortisol before and after sessions to determine if learning about the upcoming interaction with a dog reduced salivary cortisol in children. Cortisol was variable across participants, with only some deriving a potential physiological benefit from expecting to interact with the dog.     

Clinical Implications for Multi-Racial Individuals

Abstract

Multi- racial individuals experience distinctive struggles and challenges that can impact their mental health. However, despite the growing population and unique presenting issues there remains a scarcity of literature to effectively support them. In addition, there is a lack of research exploring the unique experience of the multiple heritage population. The article offers implications for effectively working with individuals of multi-racial decent as well as a call to action for MFTs to develop multicultural competencies for the profession.