纳米金材料在肿瘤诊治研究中的相关进展

目前肿瘤的早期诊断依然是需要攻克的难关,现有的抗肿瘤药物因具有较大毒性且缺乏组织特异性而存在很大的局限性.纳米金基于能够被多种基团修饰后获得对肿瘤细胞的靶向性的特点逐渐成为当前抗肿瘤研究的热点.纳米金自身具有独特的生物活性,同时具有光热效应,也可以作为载体负载药物,以上3种特点均可应用于新药物的开发,用于肿瘤诊治方面的研究.本文从这三个方面描述了近期纳米金的研究进展.     

心理疗法在针灸治疗中的应用

随着疾病谱和死亡谱的改变,生物医学模式逐渐地不能满足医学发展的需要,取而代之的是生物心理社会医学模式。现代医学模式全方位探求影响人类健康与疾病的因果关系,认为生物学、心理学及社会学因素是人类致病共同的重要因素。针灸是中国传统医学同时也是西方辅助与替代医学的重要内容。针灸医护人员应大力宣传针灸知识,应用生物心理社会医学模式去对待每一位患者。本文试述心理疗法如支持性心理治疗、认知行为疗法、放松疗法在针灸临床的应用,展现针灸心身同治的诊疗特点。     

恶性肿瘤多学科综合诊疗模式的探讨

恶性肿瘤的治疗方法和理念不断更新,依靠单一治疗方法很难取得理想效果,多学科综合诊疗（MDT）模式是以患者为中心和以多学科专家组为依托的多种诊疗模式的有机结合,保障了肿瘤患者最佳诊疗方案的实施,促进了学科间的交流和了解.资料显示,MDT是恶性肿瘤患者改善结局的最好模式.推广和完善MDT模式将有助于我国医疗资源共享,减少误诊误治,改善肿瘤患者预后,提高存活率.     

School‐based humanistic counselling for psychological distress in young people: A practice research network to address the attrition problem

Aims: School‐based humanistic counselling (SBHC) is a common psychological intervention for young people, particularly in the UK. However, studies have tended to suffer from high attrition rates, such that effects may have been over‐estimated. This paper describes a low budget ‘star topology’ practice research network (PRN) outcome evaluation of SBHC in a sample where attrition rates were minimised. Design: A practice‐based longitudinal study in a small PRN compared levels of psychological distress at first and last session from session‐by‐session data. Multilevel regression modelling was used to identify predictors of outcomes. Methods: Eight counsellors working across 11 schools agreed to use session‐by‐session self‐rating on the Young Person's CORE (YP‐CORE) yielding data from 256 young people aged 11 to 17. Predictors of outcomes were analysed using multilevel regression analysis. Results: Mean levels of distress on the YP‐CORE reduced from 18.29 (SD = 7.32) at baseline to 9.10 (SD = 6.19) at endpoint, giving a baseline to endpoint effect size of 1.26 (95% CI = 1.06–1.46). Lower levels of psychological distress at endpoint were associated with male clients, younger age groups, greater rates of attendance at counselling, and bereavement as a presenting problem. Conclusions: This ‘star topology’ PRN focused on a single study and demonstrated that such a system can provide relatively low cost, high quality data. The data showed that SBHC is associated with large reductions in psychological distress, and that this cannot be attributed to the high attrition rates of previous datasets.     

Time Perspective Therapy: A New Time-Based Metaphor Therapy for PTSD

Time perspective therapy (TPT) is a new time-based therapy that focuses on clients' perceptions of their past, present, and future. Based on Zimbardo's temporal theory and the utilization of the Zimbardo Time Perspective Inventory, the authors have developed this new narrative therapy approach for the purpose of treating clients diagnosed with posttraumatic stress disorder. The goal of TPT is to identify clients' six time perspective factors and then work with and balance these perspectives to promote a more positive future orientation, replace their traumatic past negativity, and thereby create a more responsive and healthier individual.     

Theoretical frameworks for working with harder to reach families: lines,curlicues, and spirals: comment on Donovan and Pocock

This article comments on the Donovan and Pocock articles appearing in this issue, both of which address the evolution of theory and practice in family therapy. An emphasis is placed on the importance of integration and a shared philosophy of theory and practice in our current political and economic managed care climate, in which it is critically important to embrace the integrated and chaotic whole of what is happening in theory and in practice.     

A Meta‐Analytic Review of Child‐Centered Play Therapy Approaches

The authors explored the overall effectiveness of child‐centered play therapy (CCPT) approaches through a meta‐analytic review of 52 controlled outcome studies between 1995 and 2010. Hierarchical linear modeling techniques estimated a statistically significant moderate treatment effect size (.47) for CCPT, as well as statistically significant relationships between effect size and study characteristics, including child's age, child's ethnicity, caregiver involvement, treatment integrity, publication status, and presenting issue.     

Group Narrative Therapy for Women With Attention‐Deficit/Hyperactivity Disorder

Women with attention‐deficit/hyperactivity disorder (ADHD) often struggle with the developmental challenges of adulthood and ADHD‐related problems. The authors provide specific clinical interventions from a narrative‐based group approach to help women with ADHD understand their symptoms, create strength‐based narratives, and apply these narratives to the developmental tasks of early adulthood.