肝豆状核变性（Wilson病）治疗策略的变革及思考

评析肝豆状核变性(WD)当前的治疗方法,主要有低铜饮食,铜的螯合剂青霉胺及曲恩汀,锌制剂和四硫钼酸胺,肝移植。介绍WD治疗策略的变革:不再提倡驱铜疗法以去除堆积的铜,而是使血液中的游离铜离子浓度常态化以逆转铜中毒,并结合2007年《柳叶刀》WD治疗专家共识进行思考。最后,展望未来对WD可能的根治疗法,即基因治疗、肝细胞移植及现在可施行的肝移植。     

From Social Withdrawal to Social Confidence: Evidence for Possible Pathways

Children born with a possible predisposition toward shyness face many social challenges. Researchers over the past four decades have begun to identify specific factors that influence shy children’s social skill development and their level of peer acceptance. The purpose of this article is to review factors across each developmental stage that have been found to either promote or hinder the development of social competence and peer acceptance in shy children. These factors include physiological differences, caregiver influences, emotion socialization, friendships, general peer support, coping skills, organized social activities, and socioeconomic status.     

Maternal and Paternal Perceptions of Social Competence in Children and Adolescents

We examined maternal and paternal perceptions of social competence in children and adolescents. One hundred forty-seven parents rated scenarios depicting children who varied in age, gender, and social competence. Parents also completed questionnaires assessing the amount of time they spend with their own children, their gender identity, their psychological symptoms, and their affectivity. Results indicated that the amount of time parents spend with their own children was related to maternal and paternal ratings, whereas affectivity was related to paternal ratings. In contrast, parents’ gender identity and psychological symptoms were unrelated to their ratings of social competence. Finally, there was an interaction between parent gender and the level of social competence depicted in the scenarios they rated, suggesting that there were differences in maternal and paternal ratings. These findings emphasize the importance of examining the perceptions of both mothers and fathers when assessing social competence in children and adolescents.     

雷公藤多苷对肝脏的双重作用及其思考

文献研究表明,雷公藤多苷既可治疗肝脏疾病,又能引起肝脏毒性。本文对其双重作用从不同角度进行了分析,认为药物均存在治疗作用和毒副作用的双重效应,且与用药剂量、时间密切相关,并从严控剂量时间、加强监测、重视“治未病”、改进剂型等方面提出了应对措施。     

高龄老年高血压患者的降压治疗策略

80岁以上高龄老年高血压患者的降压治疗随着人口老龄化而越来越受关注。评估高龄高血压患者降压治疗的获益与风险,在循证医学基础上进行个体化治疗,依据全身情况和耐受程度调整血压控制水平,慎重选择药物,平稳缓慢降压,将使高龄高血压患者最大程度受益。     

Good vibrations: Analytic process as coupled oscillations

This paper develops a new model for the action of psychoanalysis based on concepts from non-linear dynamics (chaos theory and complexity theory). It shows that the analyst–analysand couple may be conceptualized as a new configuration with its own properties that promote complex development in both members of the couple. These developments are an emergent result of the formation of the analyst–analysand couple and are significantly independent of the particular content of the manifest interaction of the couple. The well-studied phenomena of coupled oscillators suggest the specific features of the analysand–analyst interaction that are likely to be most important in conceptualizing analytic change. The model has substantial clinical applications since efforts to arrange for a coupled oscillator system that is central to it are distinct from many of the traditional considerations associated with creating an analytic situation.     

“We Never was Happy Living Like a Whiteman” : Mental Health Disparities and the Postcolonial Predicament in American Indian Communities

In the context of increasing attention to disparities in health status between U.S. ethnoracial groups, this article examines the dilemma of divergent cultural practices for redressing disparities in mental health status in American Indian communities. Drawing upon an ethnographic interview with a tribal elder from a northern Plains Indian reservation, a prototypical discourse of distress is presented and analyzed as one exemplar of the divergence between the culture of the clinic and the culture of the community. Situated in the context of continuing power asymmetries between tribal nations and the U.S. federal government, the implications of this cultural divergence for the efforts of mental health professionals, practitioners, and policymakers are identified as a predicament that only the conventions and commitments of a robust community psychology have the potential to resolve.     

武汉地区大学生社会能力的结构及其问卷编制

从分析大学阶段的关键性发展任务出发,将我国大学生的社会能力分为事务处理能力、一般人际交往能力和建立与发展友谊的能力三个方面。以文献研究为基础,结合开放式问卷所获资料,分别提出了关于这三种社会能力结构的理论构想,编制了大学生社会能力问卷。武汉市1048名大学生参与了正式问卷的施测,结果表明,事务处理能力的四因素结构、一般人际交往能力的五因素结构和建立与发展友谊的能力的五因素结构是较为合理的,自编大学生社会能力问卷的信效度达到心理测量学要求。     

基于胜任特征的人才测评

该文总结了国内外有关胜任特征与测评方面的文献,阐述了胜任特征作为人才测评的标准的内涵,进而总结了胜任特征应用于人才测评的作用与意义,最后简要介绍了基于胜任特征的人才测评的技术方法。本文有助于胜任特征与人才测评课题的进一步研究,对于人才测评的实践具有很强的指导意义。