Gene Concepts and Genethics: Beyond Exceptionalism

The discursive explosion that was provoked by the new genetics could support the impression that the ethical and social problems posed by the new genetics are somehow exceptional in their very nature. According to this view we are faced with special ethical and social problems that create a challenge so fundamental that the special label of genethics is needless to justify. The historical account regarding the evolution of the gene concepts could serve us to highlight the limits of what we know about genes and what we can do with genes. The widespread notion about the exceptionality of genetic knowledge and its applicative possibilities is hardly justifiable and leads to misunderstandings regarding the conceptualization of the ethical and social problems we might face. Following a more realistic interpretation of the role of genes in human life we might avoid a whole set of fictive dilemmas and counterproductive regulatory efforts in bioethics. Bioethical discourse should move from the gene-centered scientific discourse toward the more sophisticated and complex discourses where human development represented as a matter of complex interactions between genomes and environments, between genes, educational factors, nutritional regimes, and other different developmental resources. If a gene is seen as one among the different developmental resources that are shaping a given human trait then both genethics and genetic exceptionalism could hardly be represented as a justified approach in discussing the ethical and social problems of genetics.     

An Invitation to Behavior Analysts: Review of in Search of Memory: The Emergence of A New Science of Mind by Eric R. Kandel

This fascinating autobiography and multifaceted case history in neuroscience research is accessible to laymen and potentially instructive to working scientists. Kandel takes the reader through his thought processes as he describes experiments that led to some of the past decades'' major neuroscience discoveries (some highlights of which are summarized in the review''s Appendix), and eventually to his Nobel Prize. The review analyzes some of the terminological and conceptual issues that have often inhibited communication between behavior analysts and neuroscientists, with special attention to some of Bennett and Hacker''s admonitions viewed from the perspective of language evolution and linguistics. The review then discusses opportunities for behavior analysts to collaborate with neuroscientists by applying behavioral contingency analysis to help specify the independent variables of neuroscience experiments described by Kandel. Finally, it examines Kandel''s provocative heuristics for locating important research problems, and the lessons that can be gleaned from the book regarding the attributes of potentially great achievers.     

POLITICS: Automated ideological reasoning

POLITICS is a system of computer programs which simulates humans in comprehending and responding to world events from a given political or ideological perspective. The primary theoretical motivations were: (1) the implemention of a functional system which applies the knowledge structures of Schank and Abelson (1977) to the domain of simulating political belief systems; (2) the development of a tentative theory of intentional goal conflicts and counterplanning. Secondary goals of the POLITICS project include developing a representation for belief systems, investigating cognitive processes such as goal-directed inferencing, and the integration of several types of knowledge representations into a functional system.     

Dynamiques représentationnelles et identitaires au cours de la socialisation professionnelle de jeunes recrues LGBT

This article examines the ways in which representational and identity transformations work during the socialization in the workplace of young LGBT hires, linked to discrimination perceived in their workplace environment as well as their impact on professional goals. Working within the theoretical framework of active socialization, the study is based on the IMIS method and proposes a detailed analysis of two cases recently entering the transportation workplace. The results show that, depending on how severe the perceived discrimination is in the workplace, previous experiences of homophobia encountered in other environments and already built self-image are reactivated in different ways, leading to a more or less important reconstruction of professional and identity representations, as well as the future goals of the individual. These elements are discussed from the point of view of interactions between environments and possible interventions by valuing diversity and accompanying the integration of young hires into organizations.     

Intelligence and fertility in the United States: 1912-1982

Results are presented for the 1st analysis of the relationship between IQ and completed fertility using a large, representative sample of the US population. Correlations are predominantly negative for cohorts born between 1894 and 1964 but are significantly more positive for cohorts whose fertility was concentrated in the baby boom years. Previous studies reporting slightly positive correlations appear to have been biased in their restriction of samples to atypical cohorts. The National Opinion Research Center (NORC), a nonprofit research organization affiliated with the University of Chicago, conducted the General Social Survey (GSS) in the US each year from 1972 to 1982, except for 1979. A combination of block quota and full probability sampling was employed. Hour-long interviews were completed with 12,120 respondents who were English-speaking, noninstitutionalized adults (18 years or older) living within the continental US. Such questions as age, place of birth, income and occupation, were asked in each interview. Other questions about attitudes on various social, political, and moral issues were rotated in different years. The unique opportunity this data set affords is an overview of the relationship between intelligence and fertility for a nationally representative sample of Americans whose major reproductive years fell between 1912 and 1982. Data were consolidated from the 4 surveys in which the vocabulary test was given (1974, 1976, 1978, and 1982). Respondents were divided into 15 birth cohorts of 5-year intervals ranging from before 1894 to 1964. Correlations between vocabulary scores and number of siblings are markedly negative across all 15 cohorts. Vocabulary sibling correlations are more negative in every cohort than vocabulary offspring correlations. Previous reports of a neutral or slightly eugenic relationship appear to be due to the nature of the samples used, in part because the cohorts chosen were atypical, and in part because they did not include nonwhites. Childless respondents averaged slightly higher scores than did those with 1 or more children, indicating that the automatic exclusion of the childless from sibling-IQ studies has not spuriously inflated negative correlations.     

Explanatory warrant for scientific realism

Nancy Cartwright relies upon an inference pattern known as inference to the best causal explanation (IBCE) to support a limited form of entity realism, according to which we are warranted in believing in entities that purportively cause observable effects. IBCE, as usually understood, is valid, even though all other forms of inference to the best explanation (IBE) are usually understood to be invalid. We argue that IBCE and IBE are in the same boat with respect to their ability to support realist conclusions. Either rule can be interpreted as valid, this is a matter of semantic convention. However, doing so deprives the rule of the empirical content the realist needs, requiring the realist to find independent warrant for a strong (theoretical or causal) premise. We then examine the proposed means of obtaining this warrant, and find them as inadequate in the case of IBCE as they are in the case of IBE.     

社会认知中的样例激活效应与内-外群体效应

采用信号检测论技术,以人格词单记忆为实验任务,探讨社会认知过程中样例激活效应与内-外群体效应对记忆过程的干扰作用.实验结果表明,(1)样例激活与群体范畴的交互效应对社会信息加工过程存在显著干扰作用.(2)与外群体相比,内群体的信息加工更不易受到干扰;与积极样例特质相比,消极他相关样例特质的信息加工更不易受到干扰.(3)在加工内群体成员信息而激活的是反面样例时,被试的判断标准最严.     

意见收敛定理与休谟问题

意见收敛定理是主观主义概率论的一条重要定理,它表明随着证据的增加,验前概率的主观性将被验后概率的客观性所代替。意见收敛定理被看作主观概率的动态合理性原则,因而被用来解决休谟问题,即归纳合理性问题。然而,哈金有说服力地表明,意见收敛定理证明的是条件概率Pr（h／e）的收敛,而不是验后概率Pre（h）的收敛。主观主义概率论暗中接受的一个等式是：Pre（h）=Pr（h／e）,通常称之为“条件化规则”。这样,归纳法的合理性问题变成条件化规则的合理性问题。为此,本文提出一个新的合理性原则,即“最少初始概率原则”,将它同“局部合理性”观念结合起来便可为条件化规则的合理性加以辩护。     

严格检验中医疗法有效性的理论研究

本文重点在于提出并阐释了一种证实性治法研究的设计理念——纳入标准的二重性原则：检验中成药治疗某种“西医病”是否安全有效,制定受试对象的纳入标准时既辨病又辨证,研究结论的可靠性与可重复性将更有保证;在辨病的同时应该计算四诊量化信息的离均差平方和,评价受试对象之间“对表现为某证构成标志的症状和体征”的不同程度以严格控制其证候表现上的差异。     

医护人员人文素质缺乏的管理责任及干预策略

医护人员人文素质缺乏与医学教育缺陷、人文管理意识不强、后续人文素质培养不利及执业环境恶化等综合因素密切相关。卫生行政主管部门和医院管理者首先应当确立人文管理理念,营造医院的人文氛围,承担起促进医学教育体制改革、加强岗位培训和着力培养社会需要的“人文科学型”医护人员的责任。