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91.
Warren K. Bickel Liqa N. Athamneh 《Journal of the experimental analysis of behavior》2020,113(1):48-56
The Reinforcer Pathology theory proposes conditions under which drugs emerge as excessively preferred reinforcers compared to other available reinforcers among drug users. The theory highlights 2 key variables as important determinants of drug preference: (a) excessive preference for immediate rewards (high discounting of future rewards); and (b) excessive valuation for addictive reinforcers (e.g., drugs). Two iterations of the Reinforcer Pathology theory exist with the latest iteration (i.e., Reinforcer Pathology 2.0) specifying that the temporal window of reinforcer integration (measured by delay discounting) is a determinant of reinforcer value. The 2 iterations of the Reinforcer Pathology theory are described. A novel insight and understanding of abstinence and relapse from a Reinforcer Pathology perspective, limitations, and future directions are discussed. The Reinforcer Pathology theory continues the long-standing efforts to scientifically understand and better define novel concepts and methods to further translational research and improve treatment outcomes. Exploring the complementary relation between the Reinforcer Pathology perspective and other current approaches could have a valuable effect. 相似文献
92.
Temporal control in rats: analysis of nonlocalized effects from short interfood intervals. 总被引:2,自引:2,他引:0
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The present experiment analyzed temporal control of postreinforcement pause duration during within-session changes in the criterion for reinforcement (interfood interval, IFI). Analysis of interval-by-interval changes in the pause revealed localized and nonlocalized effects from short intervals that caused specific changes in performance. In Phase 1, rats were presented with five consecutive 15-s IFIs intercalated into a series of 60-s IFIs. The 15-s set decreased the pause in adjacent and more remote 60-s intervals. In Phase 2, two sets of 15-s intervals were intercalated. The spacing between the two sets varied so that 0, 5, 10, or 15 60-s IFIs separated the sets. The postreinforcement pause tracked all changes in the IFI duration, and the localized effect from a short set extended beyond the next interval to the next few 60-s IFIs. Effects from one set, however, did not combine with a second set: Changes in the pause after two sets were the same regardless of the spacing between sets. 相似文献
93.
94.
Effects of signaling on temporal control of behavior in response‐initiated fixed intervals
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Adam E. Fox Elizabeth G. E. Kyonka 《Journal of the experimental analysis of behavior》2016,106(3):210-224
Behavior and events distributed in time can serve as markers that signal delays to future events. The majority of timing research has focused on how behavior changes as the time to some event, usually food availability, decreases. The primary objective of the two experiments presented here was to assess how behavior changes as time passes between two time markers when the first time marker was manipulated but the second, food delivery, was held constant. Pigeons were exposed to fixed‐interval, response‐initiated fixed‐interval, and signaled response‐initiated fixed‐interval 15‐ and 30‐s schedules of reinforcement. In Experiment 1, first‐response latencies were systematically shorter in the signaled response‐initiated schedules than response‐initiated schedules, suggesting that the first response was a more effective time marker when it was signaled. In Experiment 2, responding in no‐food (i.e. “peak”) trials indicated that timing accuracy was equivalent in the three schedule types. Compared to fixed interval schedules, timing precision was reduced in the signaled response‐initiated schedules and was lowest in response‐initiated schedules. Results from Experiments 1 and 2 coupled with previous research suggest that the overall “informativeness” of a time marker relative to other events and behaviors in the environment may determine its efficacy. 相似文献
95.
The conflict adaptation (CA) effect refers to the reduction in the interference effect observed in conflict tasks that follow incongruent compared to congruent trials. It has been suggested that CA is caused by the exertion of flexible cognitive control, supported by many behavioral and neuroimaging studies; however, it remains unclear how conflict‐related features of the preceding trial are conveyed to subsequent trials for following adaptation. This review aims to summarize evidence supporting the top‐down modulation of the dorsolateral prefrontal cortex and passive short‐term maintenance in the posterior brain areas as mechanisms underlying CA, respectively, and to suggest a new integrated view of CA, including active maintenance in working memory. We review empirical evidences suggesting that both dorsolateral prefrontal cortex and posterior brain regions play critical roles in CA, rather than either top‐down modulation or passive maintenance alone. Although the active maintenance view of CA appears to explain many existing findings, empirical studies are required to directly test this view. 相似文献
96.
Brady D. Nelson 《Cognition & emotion》2016,30(3):417-429
The parietal cortex is critical for several different cognitive functions, including visuospatial processing and mathematical abilities. There is strong evidence indicating parietal dysfunction in depression. However, it is less clear whether anxiety is associated with parietal dysfunction and whether comorbid depression and anxiety are associated with greater impairment. The present study compared participants with major depression (MDD), panic disorder (PD), comorbid MDD/PD and controls on neuropsychological measures of visuospatial processing, Judgement of Line Orientation (JLO), and mathematical abilities, Wide Range Achievement Test (WRAT) Arithmetic. Only comorbid MDD/PD was associated with decreased performance on JLO, whereas all psychopathological groups exhibited comparably decreased performance on WRAT Arithmetic. Furthermore, the results were not accounted for by other comorbid disorders, medication use or psychopathology severity. The present study suggests comorbid depression and anxious arousal are associated with impairment in visuospatial processing and provides novel evidence indicating mathematical deficits across depression and/or anxiety. Implications for understanding parietal dysfunction in internalising psychopathology are discussed. 相似文献
97.
98.
Dispositional optimism is typically defined in terms of generalized positive expectancies for personal future life outcomes. Yet, multiple lines of inquiry have demonstrated fundamental interconnections among all three temporal perspectives (past, present, and future). Hence, in the present work, we examine the commonality underlying dispositional optimism and individuals’ evaluations of their past, present, and anticipated future lives. Results (n = 459; 80% female; M age = 19.68) suggest that dispositional optimism loads strongly on an underlying (latent) tendency to evaluate one’s life positively across temporal perspectives. This latent tendency was significantly associated with each Big Five personality dimension; independent of this latent tendency dispositional optimism was associated only with neuroticism. Controlling for personality dimensions, the latent tendency was predictive of positive functioning (mental health, coping, physical health, and social resources); in contrast, independent of this latent tendency dispositional optimism had no significant residual associations with any of the various functioning indicators. 相似文献
99.
Simon D. Holzapfel Shannon D. R. Ringenbach Genna M. Mulvey Amber M. Sandoval-Menendez Natasha Birchfield Shreja R. Tahiliani 《Journal of Cognitive Psychology》2016,28(8):990-1003
Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n?=?17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n?=?16), or eight weeks of no cycling (np?≥?.149) and working memory improved only in the ACT group (Hedge’s g?=?1.66; p?=?.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC. 相似文献
100.
高压氧对小鼠学习记忆及脑细胞形态结构的影响 总被引:2,自引:0,他引:2
实验用两种行为模型(旷场行为模型和Y-迷宫分辨学习模型)观察了幼龄小鼠在不同压力的高压氧处理后,对新异环境的探究行为和自发活动情况,以及学习记忆能力的变化;并用XY-生物医学电脑图像分析仪分析了与学习记忆相关的脑区(大脑皮层、海马)神经元密度,细胞核面积,胞核/胞浆比值的变化。结果表明:(1)与对照组相比,吸0.1MPa高压氧的幼鼠学习记忆能力明显提高,相关脑区的神经元密度、细胞核面积、胞核/浆比均显著增加。(2)吸0.25MPa高压氧的幼鼠学习记忆能力与对照组相比无明显变化,但其在新异环境中的自发行为明显减少。提示:慢性吸入0.1MPa高压氧有利于促进幼鼠脑的生长发育,增强脑功能活动。 相似文献