Properties of bootstrap tests for N‐of‐1 studies

N‐of‐1 study designs involve the collection and analysis of repeated measures data from an individual not using an intervention and using an intervention. This study explores the use of semi‐parametric and parametric bootstrap tests in the analysis of N‐of‐1 studies under a single time series framework in the presence of autocorrelation. When the Type I error rates of bootstrap tests are compared to Wald tests, our results show that the bootstrap tests have more desirable properties. We compare the results for normally distributed errors with those for contaminated normally distributed errors and find that, except when there is relatively large autocorrelation, there is little difference between the power of the parametric and semi‐parametric bootstrap tests. We also experiment with two intervention designs: ABAB and AB, and show the ABAB design has more power. The results provide guidelines for designing N‐of‐1 studies, in the sense of how many observations and how many intervention changes are needed to achieve a certain level of power and which test should be performed.     

New developments in transference focused psychotherapy

This paper will summarize recent clinical developments in the treatment of borderline patients at the Personality Disorders Institute at Cornell. The experiences under review will include the careful, ongoing monitoring of developments in the patient's life outside the sessions, and their consideration in diagnosing affective dominance during the hours. Other issues include the discussion of a ‘second chance’ approach to contract violations; the assessment and concern with the patient's assumption of responsibility for himself; the contradictions between actual behavior patterns and life goals, and between personality potentials and present functioning; the technical implications of particular constellations of regressive narcissistic features; drug dependence and antisocial behavior; and life goals and treatment goals.     

The Combined Effects of Measurement Error and Omitting Confounders in the Single-Mediator Model

Mediation analysis requires a number of strong assumptions be met in order to make valid causal inferences. Failing to account for violations of these assumptions, such as not modeling measurement error or omitting a common cause of the effects in the model, can bias the parameter estimates of the mediated effect. When the independent variable is perfectly reliable, for example when participants are randomly assigned to levels of treatment, measurement error in the mediator tends to underestimate the mediated effect, while the omission of a confounding variable of the mediator-to-outcome relation tends to overestimate the mediated effect. Violations of these two assumptions often co-occur, however, in which case the mediated effect could be overestimated, underestimated, or even, in very rare circumstances, unbiased. To explore the combined effect of measurement error and omitted confounders in the same model, the effect of each violation on the single-mediator model is first examined individually. Then the combined effect of having measurement error and omitted confounders in the same model is discussed. Throughout, an empirical example is provided to illustrate the effect of violating these assumptions on the mediated effect.     

An analysis of factors affecting wrong-way driving at a highway entrance using a driving simulator among older drivers with cognitive decline

About 200 highway wrong-way driving cases occur annually in Japan, of which about 70% are caused by older drivers. The number of these cases has remained consistent despite adoption of full-fledged measures against wrong-way driving, thus demonstrating the need for further measures. Reports indicate that older drivers include those with cognitive decline. Moreover, it has been revealed that drivers over 75 years of age who caused wrong-way driving had lower test scores in the usual cognitive function tests performed at the time of licence renewal. However, there is no clear evidence on the relationship between cognitive decline and driving behaviour that stimulates wrong-way driving. In this paper, we reproduced a wrong-way driving approaching a right turn to an expressway exit in a virtual environment using a driving simulator for older drivers, including those with mild cognitive impairment (MCI). In addition to the measurement of driving behaviour and eye-tracking during simulator driving, we conducted a cognitive function test to investigate the relationship between driving behaviour and visual behaviour factors that initiate reverse running and cognitive decline. The results revealed that the reason for the start of a highway wrong-way driving may be a human error at the recognition stage of overlooking a visual wrong-way driving countermeasure, or a human error at the judgement stage of failing to suppress action despite noticing the visual countermeasure. Additionally, attentional and executive functions were related to the wrong-way initiative, although MCI did not affect it. This suggests that those who could not control their wrong-way driving behaviour despite observing the signs had specific executive function deficits.     

如何减少医疗差错

医疗差错是危及医疗安全、制约医疗质量、影响医患关系、引发医患纠纷的核心问题,是医院管理的重点和难点。本文通过对医疗差错的分析和美国七大减少医疗差错的借鉴来探讨如何结合我国医院的实际来有效地减少医疗差错的发生。     

Sense of agency, associative learning, and schizotypy

Despite the fact that the role of learning is recognised in empirical and theoretical work on sense of agency (SoA), the nature of this learning has, rather surprisingly, received little attention. In the present study we consider the contribution of associative mechanisms to SoA. SoA can be measured quantitatively as a temporal linkage between voluntary actions and their external effects. Using an outcome blocking procedure, it was shown that training action–outcome associations under conditions of increased surprise augmented this temporal linkage. Moreover, these effects of surprise were correlated with schizotypy scores, suggesting that individual differences in higher level experiences are related to associative learning and to its impact on SoA. These results are discussed in terms of models of SoA, and our understanding of disrupted SoA in certain disorders.     

Proximal Antecedents and Correlates of Adopted Error Approach: A Self-Regulatory Perspective

ABSTRACT

The current study aims to further investigate earlier established advantages of an error mastery approach over an error aversion approach. The two main purposes of the study relate to (1) self-regulatory traits (i.e., goal orientation and action-state orientation) that may predict which error approach (mastery or aversion) is adopted, and (2) proximal, psychological processes (i.e., self-focused attention and failure attribution) that relate to adopted error approach. In the current study participants' goal orientation and action-state orientation were assessed, after which they worked on an error-prone task. Results show that learning goal orientation related to error mastery, while state orientation related to error aversion. Under a mastery approach, error occurrence did not result in cognitive resources “wasted” on self-consciousness. Rather, attention went to internal-unstable, thus controllable, improvement oriented causes of error. Participants that had adopted an aversion approach, in contrast, experienced heightened self-consciousness and attributed failure to internal-stable or external causes. These results imply that when working on an error-prone task, people should be stimulated to take on a mastery rather than an aversion approach towards errors.     

Overpredicting and Underprofiting in Pricing Decisions

This research examines sellers' price‐setting behavior and discovers a naturally occurring mismatch between sellers and buyers: Sellers who make a price decision often consider alternative prices and engage in the joint evaluation mode, whereas buyers who make a purchase decision see only the finally set price and are in the single evaluation mode. This mismatch in evaluation modes leads sellers to overpredict buyers' price sensitivity and underprice their products. However, these effects apply only to products unfamiliar to buyers and without salient reference prices and can be alleviated if sellers are encouraged to mimic single evaluation when making pricing decisions. These propositions are empirically tested and verified. Copyright © 2011 John Wiley & Sons, Ltd.     

Ironic effects of performance are worse for neurotics

ObjectivesTo conduct the first examination of neuroticism as a predictor of (1) the incidence of what Wegner (1989, 2009) terms ironic processes of mental control and (2) the precision of ironic performance errors under high- and low-anxiety conditions.DesignAcross two studies we employed a repeated-measures design.MethodIn a football penalty-shooting task (Study 1) and a dart-throwing (Study 2) task, under high-anxiety and low-anxiety conditions, participants gained maximum points for hitting a target zone and fewer points for hitting a designated non-ironic error zone. Additionally, we instructed participants to be particularly careful not to hit a designated ironic error zone, because such hits would score minimum points.ResultsAcross both studies within-subjects moderation analyses revealed a consistent moderating effect of neuroticism on the incidence of ironic errors in the high-anxiety condition. Specifically, when anxious, neurotics displayed a significant increase in ironic performance error and a significant decrease in target hits. Importantly, non-ironic error did not differ across anxiety conditions. Additionally, Study 2 results revealed that neuroticism moderated the precision of ironic errors when anxious. Specifically, when anxious, neurotics' ironic error zone hits were significantly farther from the target zone and significantly farther into the ironic error zone than their relatively emotionally stable counterparts’ errors.ConclusionWe provide the first evidence that neuroticism moderates both the incidence and precision of ironic performance errors. These results will enable practitioners in coaching environments to make evidence-based predictions and interventions regarding which individuals are most prone to ironic performance breakdown when anxious.