Iteration of Partially Specified Target Matrices: Application to the Bi-Factor Case

The current study proposes a new bi-factor rotation method, Schmid-Leiman with iterative target rotation (SLi), based on the iteration of partially specified target matrices and an initial target constructed from a Schmid-Leiman (SL) orthogonalization. SLi was expected to ameliorate some of the limitations of the previously presented SL bi-factor rotations, SL and SL with target rotation (SLt), when the factor structure either includes cross-loadings, near-zero loadings, or both. A Monte Carlo simulation was carried out to test the performance of SLi, SL, SLt, and the two analytic bi-factor rotations, bi-quartimin and bi-geomin. The results revealed that SLi accurately recovered the bi-factor structures across the majority of the conditions, and generally outperformed the other rotation methods. SLi provided the biggest improvements over SL and SLt when the bi-factor structures contained cross-loadings and pure indicators of the general factor. Additionally, SLi was superior to bi-quartimin and bi-geomin, which performed inconsistently across the types of factor structures evaluated. No method produced a good recovery of the bi-factor structures when small samples (N = 200) were combined with low factor loadings (0.30–0.50) in the specific factors. Thus, it is recommended that larger samples of at least 500 observations be obtained.     

Disjunction and conjunction fallacies in episodic memory

It has recently been found that episodic memory displays analogues of the well-known disjunction and conjunction fallacies of probability judgement. The aim of the present research was, for the first time, to study these memory fallacies together under the same conditions, and test theoretical predictions about the reasons for each. The focus was on predictions about the influence of semantic gist, target versus context recollection, and proactive versus retroactive interference. Disjunction and conjunction fallacies increased in conditions in which subjects were able to form semantic connections among list words. In addition, disjunction fallacies were increased by manipulations that minimised proactive interference, whereas conjunction fallacies were increased by manipulations that minimised retroactive interference. That pattern suggests that disjunction fallacies are more dependent on target recollection, whereas conjunction fallacies are more dependent on context recollection.     

语言理解转换中非目标语言影响目标语言的时间进程

运用跨语言即时启动和延时启动范式,要求被试完成生物属性的语义判断任务,研究语言理解转换中非目标语言影响目标语言语义理解的时间进程。实验1非目标语言为英文,目标语言为中文,结果表明,无论是即时启动(t = -0.423, p = 0.676),还是延时启动(t = -0.82, p = 0.419),语义相关组与语义无关组都无显著差异。实验2非目标语言为中文,目标语言为英文,结果表明,在即时启动条件下,语义相关组显著快于语义无关组(t = -3.05, p = 0.006),但延时条件下语义相关组与语义无关组无显著差异(t = -0.63, p = 0.536)。综合两个实验结果表明,晚期熟练双语者在双语语言理解转换过程中语义的即时启动影响存在不对称性,语义相关的非目标语言中文对目标语言英文语义理解起促进作用;但是语义启动效应没有得到延时体现。     

抗血管生成靶向药物相关性高血压

高血压是抗血管生成靶向药物最常见的副作用之一,其机制和管理受到重视。本文就靶向药物导致高血压的机制进行了探讨,考虑可能与抗血管生成药物的作用靶点有关,即影响了血管内皮生长因子的功能所致;介绍临床如何进行高血压管理并建议在抗血管生成靶向药物使用过程中规范地监测、控制血压,开展相关研究。     

疼痛条件下时间目标对时距估计的影响

本研究采用冷压任务引发疼痛,以健康大学生为被试,试图探讨在疼痛条件下时间目标对时距估计的影响。结果发现：疼痛条件下的时距估计值小于非疼痛条件下时距估计值,疼痛条件下具体时间目标的时距估计值显著大于无目标时距估计值。临床上给患者提供具体的时间目标或许有助于他们应对疼痛。     

词边界信息在中文阅读眼跳目标选择中的作用：来自中文二语学习者的证据

采用EyeLink 1000眼动仪, 选取韩、美、日、泰四国留学生各20名, 在正常无空格和词间空格两种呈现方式下阅读中文语句, 以此来探讨二语学习者在阅读中文时词边界信息在眼跳目标选择中的作用。结果发现, 二语学习者在中文阅读中存在着一致的眼动模式, 即在单次注视事件中, 倾向于注视词的中间部分, 在多次注视事件中, 倾向于注视其开端部分, 然后再计划一次词内再注视。词边界信息能够有效地引导中文二语学习者的眼动行为和眼跳计划, 更多地将首次注视位置落在词的中间部分。最后, 词边界信息在眼跳目标选择中的促进作用没有受到母语文本呈现方式熟悉性的调节。我们认为, 中文二语学习者在阅读中的眼跳目标选择可能采用的是战略-战术策略。     

循证医学与靶向治疗——心血管病治疗前沿领域的辩证思考

循证医学与靶向治疗均透露着哲学的智慧,体现着哲学思想。循证医学符合现代医学科学性、先进性、系统性要求,集中体现了科学的医学认识论和实践观：靶向冶疗理论认为疾病的产生有具体的原因,最好的治疗是从病因学的角度,从基因蛋白的水平找准靶点进行治疗,靶向治疗理论贯穿了唯物主义可知论的观点。在心血管病治疗的临床实践中我们应当将循证医学与靶向治疗两者有机地统一,通过优势互补,取长补短,弥补两种方法各自的不足,发扬其长处,共同促进心血管病治疗学的发展。     

非小细胞肺癌靶向药物治疗争论热点

非小细胞肺癌作为全球和我国发病率最高、死亡人数最多的恶性肿瘤,其药物治疗始终是临床肿瘤学界高度关注的焦点之一。肿瘤的药物治疗模式从单纯以细胞毒药物杀伤肿瘤逐步向调节信号传导通路转变,分子靶向药物日益成为治疗肿瘤的重要武器。回顾肺癌靶向治疗的进展,诸多问题需要解决。     

归因过程“背景效应假设”的初步实验研究

通过两个实验考证了归因过程的“背景效应假设”：实验1表明,当要求活动者和观察者采用同样的背景事件时．他们之间的归因差异消失了;实验2表明,当有其它的背景信息可供参考时,被试就不再完全按照Kelley所假定的一致性和区别性信息进行归因推断。