Individual Differences in Spatial Memory and Striatal ChAT Activity among Young and Aged Rats

Individual differences in spatial memory among young and aged rats were assessed using memory tasks related to integrity of the hippocampus and the neostriatum. Relationships were then examined between measures of spatial memory and regional choline acetyltransferase (ChAT) activity, a marker for cholinergic integrity. Twenty-four-month-old Long-Evans rats were impaired in comparisons with 6-month-old rats on measures of place learning, working memory, reference memory, and perseveration in water-maze tasks. Aged rats that were impaired on one measure of memory, however, were not necessarily impaired on other measures. ChAT activity in the ventromedial and dorsolateral neostriatum of aged rats was significantly reduced in comparisons with young rats whereas no difference was found in the hippocampus. Aged rats with the most ChAT activity in the anterior ventromedial neostriatum performed best on the place-learning and reference memory tasks but also made the most perseverative errors on the working memory task. In addition, young and aged rats with the most ChAT activity in the anterior dorsolateral neostriatum were those with the least accurate working memory. No relationships were found between ChAT activity in the hippocampus and spatial memory. Thus age-related memory impairment has components that can be segregated by measuring relationships between cholinergic integrity in subregions of the anterior neostriatum and memory tasks with different strategic requirements.     

Using self-determination theory to promote adolescent girls' physical activity: Exploring the theoretical fidelity of the Bristol Girls Dance Project

ObjectivesTo report the theory-based process evaluation of the Bristol Girls' Dance Project, a cluster-randomised controlled trial to increase adolescent girls' physical activity.DesignA mixed-method process evaluation of the intervention's self-determination theory components comprising lesson observations, post-intervention interviews and focus groups.MethodFour intervention dance lessons per dance instructor were observed, audio recorded and rated to estimate the use of need-supportive teaching strategies. Intervention participants (n = 281) reported their dance instructors' provision of autonomy-support. Semi-structured interviews with the dance instructors (n = 10) explored fidelity to the theory and focus groups were conducted with participants (n = 59) in each school to explore their receipt of the intervention and views on the dance instructors' motivating style.ResultsAlthough instructors accepted the theory-based approach, intervention fidelity was variable. Relatedness support was the most commonly observed need-supportive teaching behaviour, provision of structure was moderate and autonomy-support was comparatively low. The qualitative findings identified how instructors supported competence and developed trusting relationships with participants. Fidelity was challenged where autonomy provision was limited to option choices rather than input into the pace or direction of lessons and where controlling teaching styles were adopted, often to manage disruptive behaviour.ConclusionThe successes and challenges to achieving theoretical fidelity in the Bristol Girls' Dance Project may help explain the intervention effects and can more broadly inform the design of theory-based complex interventions aimed at increasing young people's physical activity in after-school settings.     

Statistical Learning Is Not Affected by a Prior Bout of Physical Exercise

This study examined the effect of a prior bout of exercise on implicit cognition. Specifically, we examined whether a prior bout of moderate intensity exercise affected performance on a statistical learning task in healthy adults. A total of 42 participants were allocated to one of three conditions—a control group, a group that exercised for 15 min prior to the statistical learning task, and a group that exercised for 30 min prior to the statistical learning task. The participants in the exercise groups cycled at 60% of their respective O₂max. Each group demonstrated significant statistical learning, with similar levels of learning among the three groups. Contrary to previous research that has shown that a prior bout of exercise can affect performance on explicit cognitive tasks, the results of the current study suggest that the physiological stress induced by moderate‐intensity exercise does not affect implicit cognition as measured by statistical learning.     

A pilot study of women’s affective responses to common and uncommon forms of aerobic exercise

Objective: To test the extent to which participants exposed to an uncommon versus common exercise stimulus would result in more favourable affect at post-task.

Design: Experimental design. Participants (N = 120), American women aged 18–45 years, were randomly assigned to complete 30-min of either the uncommon (HOOP; n = 58) or common (WALK; n = 62) exercise stimulus.

Main outcome measures: Self-reported affect and intentions for future exercise were measured before and after the 30-min exercise bout.

Results: Analyses of covariance were run to compare post-task affect across the HOOP and WALK conditions. At post-task, participants assigned to HOOP reported more positively valenced affect, higher ratings of positive activated affect, lower ratings of negative deactivated affect, and stronger intentions for future aerobic exercise compared to participants assigned to WALK.

Conclusions: Participants who completed an uncommon bout of aerobic exercise (HOOP) reported more favourable affect post-exercise, as well as stronger intentions for future exercise, compared to participants who completed a common bout of aerobic exercise (WALK). Future work using a longitudinal design is needed to understand the relationships between familiarity with an exercise stimulus, affective responses to exercise, motivation for future exercise behaviour and exercise maintenance over time.     

Self-efficacy,planning, and preparatory behaviours as joint predictors of physical activity: A conditional process analysis

Objective: Planning can bridge the gap between intentions and action, but what bridges the gap between planning and action? This study helps to answer the question by disentangling the interrelationships between self-efficacy, planning and preparatory behaviours in predicting physical activity. Preparatory behaviours are tested as a working mechanism of planning. Moreover, it is tested whether the utility of preparatory behaviours depends on an individual’s level of self-efficacy.

Methods: A survey assessed planning, self-efficacy and preparatory behaviours for physical activity. Adults (N = 166) provided data at two measurement points. In a longitudinal model, preparatory behaviours were specified as a mediator between planning and physical activity. Self-efficacy was specified as a possible moderator at two points in the model.

Results: Preparatory behaviours mediated the relationship between planning and physical activity. An interaction between self-efficacy and preparatory behaviours on physical activity was found, indicating that individuals with low self-efficacy beliefs were more active if they engaged more frequently in preparatory behaviours.

Conclusion: Planning seems to stimulate preparatory behaviours, which in turn make future physical activity more likely. Furthermore, as performing preparatory behaviours represent a step forward towards the enactment of behavioural goals, preparatory behaviours may be particular beneficial for individuals afflicted by self-doubts regarding physical activity.     

论医疗行为中的“可容性危险”原则

对合法的医疗行为进行认定,分析医疗的局限性和社会认知差异,认为在医疗活动中,为谋求对疾病认识,应允许医疗活动带有危险性。对可容性危险原则进行法理分析,结合实际案例,分析医疗行为中的“可容性危险”原则的运用以及司法界对该原则的认知。     

男性择偶策略改变的前提：自感配偶价值提高

研究分为问卷调查与实验研究两部分。首先,40名女性和33名男性完成有关自感配偶价值评价（SPMV）和择偶偏爱策略的问卷调查,问卷调查结果是实验研究中数据分析的基线。其次,第二部分实验开始后,被试会得到实验者编造的他人潜在择偶对象的积极正面评价,其目的在于提高被试的SPMV。可以假设,男性的SPMV与随意性行为的认同或追求有正相关,男性SPMV的提高将会更加偏爱短期的性策略;女性SPMV与随意性行为不存在相关,女性SPMV的提高不会改变女性的性策略。研究结果显示,SPMV高基线水平的男性更加认可随意性行为,男性SPMV的提高与短期策略选择的增加有关。另外,SPMV提高,而不是一般自尊的提高,与择偶策略的改变具有相关。本研究结果没有证实,与长期稳定的性关系相比,SPMV的基线水平或是提高与女性对随意性行为的认同或追求之间存在相关     

Institutional Insights for Analysing Strategic Manoeuvring in the British Prime Minister’s Question Time

This paper aims at creating an adequate theoretical basis for a systematic integration of institutional insights into the pragma-dialectical analysis of argumentative exchanges that occur in institutionalised contexts. The argumentative practice of Prime Minister’s Question Time in the British House of Commons is examined, as a case in point, in order to illustrate how the knowledge of the characteristics of an institution, its rules and conventions can be integrated into the pragma-dialectical analysis. The paper highlights the role that theoretical concepts and tools such as strategic manoeuvring, argumentative activity types and dialectical profiles play in this integration.

Exercise type relates to inhibitory and error processing functions in older adults

ABSTRACT

This study investigated the association between exercise type and inhibition of prepotent responses and error detection. Totally, 75 adults (M = 68.88 years) were classified into one of three exercise groups: those who were regular participants in open- or closed-skill forms of exercise, and those who exercised only irregularly. The participants completed a Stroop and task-switching tasks with event-related brain potentials (ERPs) recorded. The results revealed that regular exercisers displayed faster reaction times (RTs) in the Stroop task compared with irregular exercisers. The open-skill exercisers exhibited smaller N200 and larger P300a amplitudes in the Stroop task compared with irregular exercisers. Furthermore, the open-skill exercisers showed a tendency of shorter error-related negativity latencies at the task-witching test. The findings suggest that older adults may gain extra cognitive benefits in areas such as inhibition functioning and error processing from participating in open-skill forms of physical exercises.     

错误相关负波（ERN）在精神病理学研究中的应用

错误相关负波（error-related negativity, ERN）是由行为错误诱发的一种脑电波成分,最大峰值在错误反应之后的50ms左右,偶极子源定位于前扣带回（anterior cingulate cortex, ACC）附近。错误加工（error processing）的经典研究范式中出现的ERN成分可能反映了ACC具有错误检测、冲突监控、强化学习、情绪动机等功能。大量研究表明过度的和不足的错误相关脑活动（hyperactive and hypoactive error processing）可能分别与精神病理学的内化性和外化性障碍（internalizing and externalizing disorders）相关联。内化性和外化性障碍的内表型（endophenotype）的研究,还存在许多值得进一步探索的问题。